Travel from Karlsruhe to Milan

Bus or train from Karlsruhe to Milan?

German Railways (DB) operates a train from Karlsruhe to Milan once daily. Tickets cost $100 - $160 and the journey takes 6 h 25 min. Alternatively, FlixBus operates a bus from Karlsruhe to Milan 4 times a day. Tickets cost $35 - $60 and the journey takes 8 h 15 min. Milan Metro also services this route every 20 minutes.

Travel Guides

Want to know more about Flixbus?Rome2rio’s guide has all the details
Getting to Milan from the airportGet the details in Rome2rio’s airport-to-city travel guide
Italian Lakes: Getting around by trainRome2rio's tips and tricks to make your journey as smooth as possible

How to get from Karlsruhe to Milan

From Karlsruhe Hauptbahnhof train to Milano Centrale. 6 h 25 min 108€. From Karlsruhe Hbf train to Basel SBB then train to Milano Centrale. 6 h 53 min 171€. From Karlsruhe bus to lampugnano m1 then line 68 bus to conciliazione m1. 8 h 42 min 48€. From Karlsruhe Hauptbahnhof nighttrain to Zuerich Hb then train to Milano Centrale. 8 h 22 min 71€. From Karlsruhe drive to Milan. 5 h 24 min 80€. From Karlsruhe Hbf train to Stuttgart Hbf (tief), train to Stuttgart airport, fly to Milan Malpensa airport, then train to Milan. 5 h 21 min 84€. From Karlsruhe Hbf train to Mannheim Hbf, train to Frankfurt airport, fly to Milan Linate airport, then line 73 bus to Milan. 5 h 19 min 140€. From Karlsruhe Hbf train to Mannheim Hbf, train to Frankfurt airport, fly to Milan Malpensa airport, then train to Milan. 5 h 48 min 142€. From Karlsruhe Hbf train to Basel SBB, train to Zürich HB, train to Zurich airport, fly to Milan Malpensa airport, then train to Milan. 5 h 58 min 208€. From Karlsruhe Hbf train to Stuttgart Hbf (tief), train to Stuttgart airport, fly to Zurich airport, line 2 train to Zuerich Hb, then train to Milan. 7 h 44 min 162€. From Karlsruhe Hbf train to Basel SBB, train to Zürich HB, train to Zurich airport, fly to Lugano airport, line 60 train to Lugano, then train to Milan. 7 h 239€.

Is there a direct train between Karlsruhe and Milan?

Yes, there is a direct train departing from Karlsruhe Hauptbahnhof and arriving at Milano Centrale. Services depart once daily. The journey takes approximately 6½ hours.

Is there a direct bus between Karlsruhe and Milan?

No, there is no direct bus from Karlsruhe to Milan. However, there are services departing from Karlsruhe and arriving at conciliazione m1 via lampugnano m1. The journey, including transfers, takes approximately 8 h 42 min.
Close Print Itinerary
  1. Here are 11 options to get from
    Karlsruhe to Milan:

    1. Trip:
      1 Train
      • One-Way approx: USD $100 - $160
      • Duration: 6 h 25 min
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      • Trip:
        1 Train
        • One-Way approx: USD $100 - $160
        • Duration: 6 h 25 min
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    2. Trip:
      2 Train Swiss Railways (SBB/CFF/FFS)
      • One-Way approx: USD $128 - $227
      • Duration: 6 h 53 min
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      • Trip:
        2 Train Swiss Railways (SBB/CFF/FFS)
        • One-Way approx: USD $128 - $227
        • Duration: 6 h 53 min
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    3. Trip:
      3 Bus
      • One-Way approx: USD $36 - $61
      • Duration: 8 h 42 min
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      • Trip:
        3 Bus
        • One-Way approx: USD $36 - $61
        • Duration: 8 h 42 min
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    4. Trip:
      4 Nighttrain, train
      • One-Way approx: USD $73 - $101
      • Duration: 8 h 22 min
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      • Trip:
        4 Nighttrain, train
        • One-Way approx: USD $73 - $101
        • Duration: 8 h 22 min
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    5. Trip:
      5 Drive
      • One-Way approx: USD $80 - $120
      • Duration: 5 h 24 min
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      • Trip:
        5 Drive
        • One-Way approx: USD $80 - $120
        • Duration: 5 h 24 min
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    6. Trip:
      6 Train to Stuttgart, fly to Milan Malpensa, train
      • One-Way approx: USD $68 - $188
      • Duration: 5 h 21 min
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      • Trip:
        6 Train to Stuttgart, fly to Milan Malpensa, train
        • One-Way approx: USD $68 - $188
        • Duration: 5 h 21 min
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    7. Trip:
      7 Train, train to Frankfurt, fly to Milan Linate
      • One-Way approx: USD $116 - $332
      • Duration: 5 h 19 min
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      • Trip:
        7 Train, train to Frankfurt, fly to Milan Linate
        • One-Way approx: USD $116 - $332
        • Duration: 5 h 19 min
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    8. Trip:
      8 Train, train to Frankfurt, fly to Milan Malpensa
      • One-Way approx: USD $128 - $306
      • Duration: 5 h 48 min
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      • Trip:
        8 Train, train to Frankfurt, fly to Milan Malpensa
        • One-Way approx: USD $128 - $306
        • Duration: 5 h 48 min
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    9. Trip:
      9 Train, train to Zurich, fly to Milan Malpensa
      • One-Way approx: USD $162 - $424
      • Duration: 5 h 58 min
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      • Trip:
        9 Train, train to Zurich, fly to Milan Malpensa
        • One-Way approx: USD $162 - $424
        • Duration: 5 h 58 min
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    10. Trip:
      10 Train to Stuttgart, fly to Zurich, train
      • One-Way approx: USD $131 - $316
      • Duration: 7 h 44 min
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      • Trip:
        10 Train to Stuttgart, fly to Zurich, train
        • One-Way approx: USD $131 - $316
        • Duration: 7 h 44 min
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    11. Trip:
      11 Train, train to Zurich, fly to Lugano
      • One-Way approx: USD $177 - $420
      • Duration: 7 h
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      • Trip:
        11 Train, train to Zurich, fly to Lugano
        • One-Way approx: USD $177 - $420
        • Duration: 7 h
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