There are 10 ways to get from Karlsruhe to Milan by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  6 h 25 min

  1. Take the train from Karlsruhe Hbf to Milano Centrale Ece

$120 - $220

Cheapest option

Bus Ouibus  •  10 h 46 min

  1. Take the bus from Karlsruhe to Milan Francfort-sur-le-Main > Mannheim > Karlsruhe > Stuttgart > Singen > Winterthur > Zurich > Lucerne > Milan > Turin - Gare routière

$24 - $34

8 alternative options

Train Swiss Railways (SBB/CFF/FFS)  •  6 h 53 min

  1. Take the train from Karlsruhe Hbf to Basel SBB Ice / ...
  2. Take the train from Basel SBB to Milano Centrale Eurocity / ...

$143 - $241

Bus FlixBus  •  8 h 40 min

  1. Take the bus from Karlsruhe to Milan, Milan N177 / ...

$37 - $60

Drive  •  5 h 24 min

  1. Drive from Karlsruhe to Milan 336.9 miles

$80 - $120

Bus to Stuttgart, fly to Milan Malpensa  •  5 h 5 min

  1. Take the bus from Karlsruhe to Stuttgart, Stuttgart Airport
  2. Fly from Stuttgart (STR) to Milan Malpensa (MXP) STR - MXP

$48 - $165

Train, train to Frankfurt, fly to Milan Linate  •  4 h 48 min

  1. Take the train from Karlsruhe Hbf to Mannheim Hbf
  2. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  3. Fly from Frankfurt (FRA) to Milan Linate (LIN) FRA - LIN

$117 - $348

Train, train to Frankfurt, fly to Milan Malpensa  •  5 h 17 min

  1. Take the train from Karlsruhe Hbf to Mannheim Hbf
  2. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  3. Fly from Frankfurt (FRA) to Milan Malpensa (MXP) FRA - MXP

$129 - $322

Train, train to Zurich, fly to Milan Malpensa  •  6 h 8 min

  1. Take the train from Karlsruhe Hbf to Basel SBB
  2. Take the train from Basel SBB to Zürich HB
  3. Fly from Zurich (ZRH) to Milan Malpensa (MXP) ZRH - MXP

$169 - $438

Bus to Stuttgart, fly to Zurich, train  •  7 h 24 min

  1. Take the bus from Karlsruhe to Stuttgart, Stuttgart Airport
  2. Fly from Stuttgart (STR) to Zurich (ZRH) STR - ZRH
  3. Take the train from Zuerich Hb to Milano Centrale

$103 - $293

What companies run services between Karlsruhe, Germany and Milan, Italy?

Deutsche Bahn operates a train from Karlsruhe to Milan once daily. Tickets cost $120 - $220 and the journey takes 6 h 25 min. Alternatively, FlixBus operates a bus from Karlsruhe to Milan 5 times a day. Tickets cost $35 - $60 and the journey takes 8 h 20 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Stuttgart to Milan Malpensa via Munich
Ave. Duration
2 h 50 min
When
Every day
Estimated price
$190 - $650
Flights from Stuttgart to Milan Malpensa via Frankfurt
Ave. Duration
2 h 57 min
When
Every day
Estimated price
$190 - $650
Flights from Frankfurt to Milan Linate
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$160 - $600
Flights from Frankfurt to Milan Malpensa
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$160 - $600
Flights from Frankfurt to Milan Malpensa via Munich
Ave. Duration
3 h 6 min
When
Every day
Estimated price
$150 - $500
Flights from Stuttgart to Zurich
Ave. Duration
45 min
When
Every day
Estimated price
$50 - $270
Swiss
Website
swiss.com
Flights from Stuttgart to Milan Malpensa via Zurich
Ave. Duration
2 h 38 min
When
Every day
Estimated price
$190 - $700
Flights from Frankfurt to Milan Malpensa via Zurich
Ave. Duration
2 h 50 min
When
Monday to Saturday
Estimated price
$160 - $600
Flights from Zurich to Milan Malpensa
Ave. Duration
57 min
When
Every day
Estimated price
$90 - $700
Flights from Stuttgart to Zurich
Ave. Duration
45 min
When
Every day
Estimated price
$50 - $270
Eurowings
Website
eurowings.com
Flights from Stuttgart to Milan Malpensa
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$40 - $310
Alitalia
Website
alitalia.com
Flights from Frankfurt to Milan Linate
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$170 - $750
easyJet
Website
easyjet.com
Flights from Stuttgart to Milan Malpensa
Ave. Duration
1 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$35 - $200
Luxair
Website
luxair.lu
Flights from Frankfurt to Milan Malpensa via Luxembourg
Ave. Duration
3 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$1,000 - $2,400
Train operators
Deutsche Bahn
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Karlsruhe Hbf to Milano Centrale
Ave. Duration
6 h 25 min
Frequency
Once daily
Estimated price
$120 - $220
Website
bahn.de
Train from Karlsruhe Hbf to Basel SBB
Ave. Duration
1 h 47 min
Frequency
Hourly
Estimated price
$50 - $85
Website
bahn.de
Train from Karlsruhe Hbf to Mannheim Hbf
Ave. Duration
23 min
Frequency
Every 30 minutes
Estimated price
$21 - $30
Website
bahn.de
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
30 min
Frequency
Every 30 minutes
Estimated price
$23 - $35
Website
bahn.de
Swiss Railways (SBB/CFF/FFS)
Website
sbb.ch
Train from Basel SBB to Milano Centrale
Ave. Duration
4 h 6 min
Frequency
4 times a day
Estimated price
$90 - $160
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Basel SBB to Zürich HB
Ave. Duration
53 min
Frequency
Hourly
Estimated price
$30 - $60
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Trenitalia Eurocity
Phone
+39 06 68475475
Website
trenitalia.com
Train from Basel Sbb to Milano Centrale
Ave. Duration
4 h 6 min
Frequency
3 times a day
Estimated price
$60 - $85
Website
orario.trenitalia.com
Train from Zuerich Hb to Milano Centrale
Ave. Duration
3 h 26 min
Frequency
Every 4 hours
Estimated price
$45 - $65
Website
orario.trenitalia.com
TGV
Phone
0033 892 353535
Website
tgv.com
Train from Karlsruhe Hbf to Mannheim Hbf
Ave. Duration
24 min
Frequency
3 times a day
Estimated price
$18 - $23
Website
en.oui.sncf
2nd Class
$18 - $23
1st Class
$32 - $37
Bus operators
FlixBus
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Karlsruhe to Milan, Milan
Ave. Duration
8 h 20 min
Frequency
5 times a day
Estimated price
$35 - $60
Website
flixbus.co.uk
Bus from Karlsruhe to Stuttgart, Stuttgart Airport
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$4 - $8
Website
flixbus.co.uk
Ouibus
Phone
0890715298
Website
ouibus.com
Bus from Karlsruhe to Milan
Ave. Duration
10 h 20 min
Frequency
Every 15 minutes
Estimated price
$22 - $35
Website
Ouibus

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Questions & Answers

How far is it from Karlsruhe to Milan?

The distance between Karlsruhe and Milan is 399 km. The road distance is 539 km.

What is the cheapest way to get from Karlsruhe to Milan?

The cheapest way to get from Karlsruhe to Milan is to bus which costs 19€ - 28€ and takes 10 h 46 min.

What is the fastest way to get from Karlsruhe to Milan?

The quickest way to get from Karlsruhe to Milan is to train and fly which takes 4 h 48 min and costs 95€ - 290€.

Is there a direct train between Karlsruhe and Milan?

Yes, there is a direct train departing from Karlsruhe Hbf and arriving at Milano Centrale. Services depart once daily. The journey takes approximately 6 h 25 min.

Is there a direct bus between Karlsruhe and Milan?

No, there is no direct bus from Karlsruhe to Milan. However, there are services departing from Karlsruhe and arriving at conciliazione m1 via lampugnano m1. The journey, including transfers, takes approximately 10 h 46 min.

How long does it take to get from Karlsruhe to Milan?

The train from Karlsruhe Hbf to Milano Centrale takes 6 h 25 min including transfers and departs once daily.