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There are 10 ways to get from Karlsruhe to Milan by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  6 h 25 min

  1. Take the train from Karlsruhe Hbf to Milano Centrale Ece / ...

$75 - $210

Cheapest option

Bus FlixBus  •  9 h 37 min

  1. Take the bus from Karlsruhe to Freiburg 022 / ...
  2. Take the bus from Freiburg to Milan, Milan 107 / ...

$33 - $60

8 alternative options

Train Swiss Railways (SBB/CFF/FFS)  •  6 h 53 min

  1. Take the train from Karlsruhe Hbf to Basel SBB Ice / ...
  2. Take the train from Basel SBB to Milano Centrale Eurocity / ...

$135 - $228

Bus Gruppo Di Maio  •  10 h 25 min

  1. Take the bus from Karlsruhe to Grandate - Stazione

$43 - $66

Drive  •  5 h 24 min

  1. Drive from Karlsruhe to Milan 336.9 miles

$80 - $120

Train to Frankfurt, fly to Milan Linate  •  4 h 43 min

  1. Take the train from Karlsruhe Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Milan Linate (LIN) FRA - LIN

$109 - $329

Bus to Stuttgart, fly to Milan Malpensa  •  5 h 5 min

  1. Take the bus from Karlsruhe to Stuttgart, Stuttgart Airport
  2. Fly from Stuttgart (STR) to Milan Malpensa (MXP) STR - MXP

$45 - $206

Train to Frankfurt, fly to Milan Malpensa  •  5 h 11 min

  1. Take the train from Karlsruhe Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Milan Malpensa (MXP) FRA - MXP

$120 - $302

Train, train to Zurich, fly to Milan Malpensa  •  6 h 9 min

  1. Take the train from Karlsruhe Hbf to Basel SBB
  2. Take the train from Basel SBB to Zürich HB
  3. Fly from Zurich (ZRH) to Milan Malpensa (MXP) ZRH - MXP

$172 - $434

Bus to Stuttgart, fly to Zurich, train  •  6 h 57 min

  1. Take the bus from Karlsruhe to Stuttgart, Stuttgart Airport
  2. Fly from Stuttgart (STR) to Zurich (ZRH) STR - ZRH
  3. Take the train from Zuerich Hb to Milano Centrale

$108 - $334

Questions & Answers

The cheapest way to get from Karlsruhe to Milan is to bus which costs 28€ - 55€ and takes 9 h 37 min.

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The quickest way to get from Karlsruhe to Milan is to train and fly which costs 90€ - 290€ and takes 4 h 43 min.

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No, there is no direct bus from Karlsruhe to Milan. However, there are services departing from Karlsruhe and arriving at conciliazione m1 via Freiburg and lampugnano m1. The journey, including transfers, takes approximately 9 h 37 min.

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Yes, there is a direct train departing from Karlsruhe Hbf and arriving at Milano Centrale. Services depart twice daily, and operate every day. The journey takes approximately 6 h 25 min.

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The distance between Karlsruhe and Milan is 399 km. The road distance is 539 km.

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The best way to get from Karlsruhe to Milan without a car is to train which takes 6 h 25 min and costs 65€ - 180€.

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The train from Karlsruhe Hbf to Milano Centrale takes 6 h 25 min including transfers and departs twice daily.

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Karlsruhe to Milan bus services, operated by FlixBus, depart from Karlsruhe station.

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Karlsruhe to Milan train services, operated by Deutsche Bahn, depart from Karlsruhe Hbf station.

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The best way to get from Karlsruhe to Milan is to train which takes 6 h 25 min and costs 65€ - 180€. Alternatively, you can bus, which costs 28€ - 55€ and takes 9 h 37 min.

Mode details

Map of how to get from Karlsruhe to Milan.
Launch map view
  • Distance: 249.1 miles
  • Duration: 6 h 25 min

What companies run services between Karlsruhe, Germany and Milan, Italy?

Deutsche Bahn operates a train from Karlsruhe to Milan once daily. Tickets cost $120 - $210 and the journey takes 6 h 25 min. Trenitalia Eurocity also services this route once daily. Alternatively, you can take a bus from Karlsruhe to Milan via Freiburg, Milan, Milan, and lampugnano m1 in around 9 h 37 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Milan Linate
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$160 - $600
Flights from Stuttgart to Milan Malpensa via Munich
Ave. Duration
2 h 58 min
When
Every day
Estimated price
$190 - $650
Flights from Frankfurt to Milan Malpensa
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$160 - $600
Flights from Frankfurt to Milan Malpensa via Munich
Ave. Duration
3 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $420
Flights from Stuttgart to Zurich
Ave. Duration
42 min
When
Every day
Estimated price
$50 - $270
Swiss
Website
swiss.com
Flights from Stuttgart to Milan Malpensa via Zurich
Ave. Duration
2 h 46 min
When
Every day
Estimated price
$190 - $700
Flights from Zurich to Milan Malpensa
Ave. Duration
53 min
When
Every day
Estimated price
$90 - $700
Flights from Stuttgart to Zurich
Ave. Duration
42 min
When
Every day
Estimated price
$50 - $270
Alitalia
Website
alitalia.com
Flights from Frankfurt to Milan Linate
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$170 - $750
Eurowings
Website
eurowings.com
Flights from Stuttgart to Milan Malpensa
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$40 - $310
easyJet
Website
easyjet.com
Flights from Stuttgart to Milan Malpensa
Ave. Duration
1 h 5 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$35 - $200
Luxair
Website
luxair.lu
Flights from Frankfurt to Milan Malpensa via Luxembourg
Ave. Duration
3 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$1,000 - $2,400
Train operators
Deutsche Bahn

Deutsche Bahn is the German railway company, and the largest railway operator and infrastructure owner in Europe. Based in Berlin, Deutsche Bahn was founded in 1994, and offers many different types of rail transportation including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare.

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Karlsruhe Hbf to Milano Centrale
Ave. Duration
6 h 25 min
Frequency
Once daily
Estimated price
$120 - $210
Website
bahn.de
Train from Karlsruhe Hbf to Basel SBB
Ave. Duration
1 h 47 min
Frequency
Hourly
Estimated price
$50 - $80
Website
bahn.de
Train from Karlsruhe Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
1 h 6 min
Frequency
Every 2 hours
Estimated price
$30 - $50
Website
bahn.de
Trenitalia Eurocity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Karlsruhe Hbf to Milano Centrale
Ave. Duration
6 h 25 min
Frequency
Once daily
Estimated price
$75 - $110
Website
orario.trenitalia.com
Train from Basel Sbb to Milano Centrale
Ave. Duration
4 h 6 min
Frequency
4 times a day
Estimated price
$55 - $80
Website
orario.trenitalia.com
Train from Zuerich Hb to Milano Centrale
Ave. Duration
3 h 26 min
Frequency
Every 3 hours
Estimated price
$45 - $65
Website
orario.trenitalia.com
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs. Swiss Railways codeshares with American Airlines and Swiss International Air Lines out of Zurich International Airport.

Contact Details
Website
sbb.ch
Train from Basel SBB to Milano Centrale
Ave. Duration
4 h 6 min
Frequency
Every 4 hours
Estimated price
$85 - $150
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Basel SBB to Zürich HB
Ave. Duration
1 h 12 min
Frequency
Every 15 minutes
Estimated price
$30 - $60
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Zürich HB to Milano Centrale
Ave. Duration
4 h 3 min
Frequency
Every 2 hours
Estimated price
$65 - $120
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Karlsruhe to Freiburg
Ave. Duration
1 h 35 min
Frequency
Hourly
Estimated price
$7 - $13
Website
flixbus.co.uk
Bus from Freiburg to Milan, Milan
Ave. Duration
6 h 35 min
Frequency
Every 3 hours
Estimated price
$24 - $45
Website
flixbus.co.uk
Bus from Karlsruhe to Stuttgart, Stuttgart Airport
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$4 - $8
Website
flixbus.co.uk
Gruppo Di Maio
Phone
+39 0827 34 117
Email
info@gruppodimaio.it
Website
gruppodimaio.it
Bus from Karlsruhe to Grandate - Stazione
Ave. Duration
9 h 14 min
Frequency
Once a week
Estimated price
$35 - $55
Schedules at
gruppodimaio.it
Marino Autolinee
Phone
+39 080 3112335
Email
info@marinobus.it
Website
marinobus.it
Bus from Karlsruhe to Stuttgart
Ave. Duration
1 h 5 min
Frequency
Once daily
Estimated price
$7
Schedules at
marinobus.it
Eurolines DE
Phone
+49 6196 2078-501
Email
service@eurolines.de
Website
eurolines.de
Bus from Karlsruhe Hbf to Stuttgart Airport
Ave. Duration
1 h 4 min
Frequency
4 times a week
Estimated price
$29 - $50
Website
eurolines.de

Want to know more about travelling around Italy

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Frankfurt Airport to Milan Linate Airport is the direct flight which takes 1 h 10 min.

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Karlsruhe to Milan bus services, operated by FlixBus, arrive at Milan, Milan station.

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Karlsruhe to Milan train services, operated by Deutsche Bahn, arrive at Milano Centrale station.

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Yes, the driving distance between Karlsruhe to Milan is 539 km. It takes approximately 5 h 24 min to drive from Karlsruhe to Milan.

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Alitalia and Lufthansa offer flights from Frankfurt Airport to Milan Linate Airport.

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Book your Karlsruhe to Milan train tickets online with Rome2rio.

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There are 4123+ hotels available in Milan. Prices start at $62 USD per night.

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