There are 9 ways to get from Karlsruhe to Milan by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train Trenitalia Eurocity  •  6 h 25 min

  1. Take the train from Karlsruhe Hbf to Milano Centrale Ec / ...

$75 - $210

Cheapest option

Bus  •  8 h 36 min

  1. Take the bus from Karlsruhe to Milan, Milan N177 / ...

$35 - $56

7 alternative options

Train Swiss Railways (SBB/CFF/FFS)  •  6 h 53 min

  1. Take the train from Karlsruhe Hbf to Basel SBB Ice / ...
  2. Take the train from Basel SBB to Milano Centrale Eurocity / ...

$135 - $228

Drive  •  5 h 24 min

  1. Drive from Karlsruhe to Milan 336.9 miles

$80 - $120

Train to Stuttgart, fly to Milan Malpensa  •  5 h 29 min

  1. Take the train from Karlsruhe Hbf to Stuttgart Hbf
  2. Fly from Stuttgart (STR) to Milan Malpensa (MXP) STR - MXP

$66 - $194

Train, train to Frankfurt, fly to Milan Linate  •  4 h 54 min

  1. Take the train from Karlsruhe Hbf to Mannheim Hbf
  2. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  3. Fly from Frankfurt (FRA) to Milan Linate (LIN) FRA - LIN

$114 - $348

Train, train to Frankfurt, fly to Milan Malpensa  •  5 h 18 min

  1. Take the train from Karlsruhe Hbf to Mannheim Hbf
  2. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  3. Fly from Frankfurt (FRA) to Milan Malpensa (MXP) FRA - MXP

$125 - $319

Train, train to Zurich, fly to Milan Malpensa  •  6 h 8 min

  1. Take the train from Karlsruhe Hbf to Basel SBB
  2. Take the train from Basel SBB to Zürich HB
  3. Fly from Zurich (ZRH) to Milan Malpensa (MXP) ZRH - MXP

$165 - $433

Train, train to Frankfurt, fly to Milan Bergamo  •  5 h 43 min

  1. Take the train from Karlsruhe Hbf to Mannheim Hbf
  2. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  3. Fly from Frankfurt (FRA) to Milan Bergamo (BGY) FRA - BGY

$70 - $285

Questions & Answers

The cheapest way to get from Karlsruhe to Milan is to bus which costs 30€ - 50€ and takes 8 h 36 min.

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The quickest way to get from Karlsruhe to Milan is to train and fly which costs 100€ - 310€ and takes 4 h 54 min.

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The distance between Karlsruhe and Milan is 399 km. The road distance is 539 km.

Get driving directions

The train from Karlsruhe Hbf to Milano Centrale takes 6 h 25 min including transfers and departs once daily.

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Yes, there is a direct train departing from Karlsruhe Hbf and arriving at Milano Centrale. Services depart once daily, and operate every day. The journey takes approximately 6 h 25 min.

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The best way to get from Karlsruhe to Milan without a car is to train which takes 6 h 25 min and costs 65€ - 190€.

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Map of how to get from Karlsruhe to Milan.
Launch map view
  • Distance: 249.1 miles
  • Duration: 6 h 25 min

What companies run services between Karlsruhe, Germany and Milan, Italy?

Trenitalia Eurocity operates a train from Karlsruhe to Milan once daily. Tickets cost $75 - $110 and the journey takes 6 h 25 min. Deutsche Bahn also services this route twice a week. Alternatively, FlixBus operates a bus from Karlsruhe to Milan every 4 hours. Tickets cost $30 - $55 and the journey takes 8 h 20 min. Marino Autolinee also services this route once daily.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Stuttgart to Milan Malpensa via Munich
Ave. Duration
2 h 56 min
When
Every day
Estimated price
$160 - $500
Flights from Stuttgart to Milan Malpensa via Frankfurt
Ave. Duration
2 h 57 min
When
Every day
Estimated price
$190 - $650
Flights from Frankfurt to Milan Linate
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$160 - $600
Flights from Frankfurt to Milan Malpensa
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$160 - $600
Flights from Frankfurt to Milan Malpensa via Munich
Ave. Duration
3 h 2 min
When
Every day
Estimated price
$150 - $550
Flights from Frankfurt to Milan Bergamo via Munich
Ave. Duration
3 h 12 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $550
Swiss
Website
swiss.com
Flights from Stuttgart to Milan Malpensa via Zurich
Ave. Duration
2 h 38 min
When
Every day
Estimated price
$190 - $700
Flights from Frankfurt to Milan Malpensa via Zurich
Ave. Duration
2 h 50 min
When
Every day
Estimated price
$160 - $600
Flights from Zurich to Milan Malpensa
Ave. Duration
57 min
When
Every day
Estimated price
$90 - $700
Eurowings
Website
eurowings.com
Flights from Stuttgart to Milan Malpensa
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$40 - $310
Alitalia
Website
alitalia.com
Flights from Frankfurt to Milan Linate
Ave. Duration
1 h 15 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $750
Luxair
Website
luxair.lu
Flights from Frankfurt to Milan Malpensa via Luxembourg
Ave. Duration
3 h 7 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$1,000 - $2,400
easyJet
Website
easyjet.com
Flights from Stuttgart to Milan Malpensa
Ave. Duration
1 h 5 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$35 - $200
Ryanair
Website
ryanair.com
Flights from Frankfurt to Milan Bergamo
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$27 - $210
Train operators
Trenitalia Eurocity
Phone
+39 06 68475475
Website
trenitalia.com
Train from Karlsruhe Hbf to Milano Centrale
Ave. Duration
6 h 25 min
Frequency
Once daily
Estimated price
$75 - $110
Website
orario.trenitalia.com
Train from Basel Sbb to Milano Centrale
Ave. Duration
4 h 6 min
Frequency
3 times a day
Estimated price
$55 - $80
Website
orario.trenitalia.com
Deutsche Bahn
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Karlsruhe Hbf to Milano Centrale
Ave. Duration
6 h 25 min
Frequency
Twice a week
Estimated price
$120 - $210
Website
bahn.de
Train from Karlsruhe Hbf to Basel SBB
Ave. Duration
1 h 47 min
Frequency
Hourly
Estimated price
$50 - $80
Website
bahn.de
Train from Karlsruhe Hbf to Stuttgart Hbf
Ave. Duration
52 min
Frequency
Every 30 minutes
Estimated price
$24 - $35
Website
bahn.de
Train from Karlsruhe Hbf to Mannheim Hbf
Ave. Duration
23 min
Frequency
Hourly
Estimated price
$19 - $28
Website
bahn.de
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
30 min
Frequency
Hourly
Estimated price
$21 - $35
Website
bahn.de
Swiss Railways (SBB/CFF/FFS)
Website
sbb.ch
Train from Basel SBB to Milano Centrale
Ave. Duration
4 h 6 min
Frequency
4 times a day
Estimated price
$85 - $150
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Basel SBB to Zürich HB
Ave. Duration
53 min
Frequency
Hourly
Estimated price
$30 - $60
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
TGV
Phone
0033 892 353535
Website
sncf.com
Train from Karlsruhe Hbf to Stuttgart Hbf
Ave. Duration
36 min
Frequency
Twice daily
Estimated price
$22 - $27
Website
en.oui.sncf
2nd Class
$22 - $27
1st Class
$39 - $40
Train from Karlsruhe Hbf to Mannheim Hbf
Ave. Duration
23 min
Frequency
Once daily
Estimated price
$17 - $22
Website
en.oui.sncf
2nd Class
$17 - $22
1st Class
$30 - $34
Bus operators
FlixBus
Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Karlsruhe to Milan, Milan
Ave. Duration
8 h 20 min
Frequency
Every 4 hours
Estimated price
$30 - $55
Website
flixbus.co.uk
Marino Autolinee
Phone
+39 080 3112335
Email
info@marinobus.it
Website
marinobus.it
Bus from Karlsruhe to Milano
Ave. Duration
10 h 15 min
Frequency
Once daily
Estimated price
$42
Schedules at
marinobus.it

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