There are 8 ways to get from Karlsruhe to Brussels by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  4 h 48 min

  1. Ice
  2. Ice

$92 - $136

Cheapest option

Bus FlixBus  •  7 h 35 min

  1. N136

$30 - $75

6 alternative options

Bus Eurolines FR  •  9 h 15 min

$96 - $157

Drive  •  4 h 28 min

  1. 305.9 miles

$60 - $95

Train, train to Frankfurt, fly  •  3 h 30 min

  1. FRA - BRU

$124 - $335

Train to Strasbourg, fly  •  3 h 14 min

  1. SXB - BRU

$119 - $359

Bus to Stuttgart, fly  •  4 h 47 min

  1. STR - BRU

$78 - $259

Train to Basel, fly  •  5 h 36 min

  1. BSL - BRU

$108 - $346

What companies run services between Karlsruhe, Germany and Brussels, Belgium?

You can take a train from Karlsruhe to Brussels via Köln Hbf in around 4 h 48 min. Alternatively, FlixBus operates a bus from Karlsruhe to Brussels twice daily. Tickets cost $30 - $50 and the journey takes 7 h 35 min. Eurolines DE also services this route 3 times a week.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Brussels
Ave. Duration
55 min
When
Every day
Estimated price
$100 - $380
Flights from Stuttgart to Brussels via Frankfurt
Ave. Duration
3 h 18 min
When
Every day
Estimated price
$200 - $750
Flights from Stuttgart to Brussels via Munich
Ave. Duration
3 h 10 min
When
Every day
Estimated price
$200 - $750
Flights from Basel to Brussels via Frankfurt
Ave. Duration
2 h 53 min
When
Every day
Estimated price
$180 - $800
Brussels Airlines
Website
brusselsairlines.com
Flights from Frankfurt to Brussels
Ave. Duration
55 min
When
Every day
Estimated price
$100 - $380
Flights from Strasbourg to Brussels
Ave. Duration
55 min
When
Monday to Friday
Estimated price
$140 - $700
Flights from Stuttgart to Brussels
Ave. Duration
1 h 20 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$60 - $460
Flights from Basel to Brussels
Ave. Duration
1 h 7 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$70 - $1,000
Swiss
Website
swiss.com
Flights from Stuttgart to Brussels via Zurich
Ave. Duration
3 h 8 min
When
Every day
Estimated price
$210 - $750
Flights from Basel to Brussels
Ave. Duration
1 h 7 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$70 - $1,000
Aegean Airlines
Website
aegeanair.com
Flights from Frankfurt to Brussels
Ave. Duration
55 min
When
Every day
Estimated price
$100 - $380
Flights from Strasbourg to Brussels
Ave. Duration
50 min
When
Monday
Estimated price
$190 - $800
Eurowings
Website
eurowings.com
Flights from Stuttgart to Brussels
Ave. Duration
1 h 20 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$60 - $460
KLM
Website
klm.com
Flights from Stuttgart to Brussels via Amsterdam
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$150 - $490
easyJet
Website
easyjet.com
Flights from Basel to Brussels
Ave. Duration
1 h 10 min
When
Monday, Thursday, Friday and Sunday
Estimated price
$45 - $290
Tarom
Website
tarom.ro
Flights from Strasbourg to Brussels
Ave. Duration
1 h 5 min
When
Monday
Estimated price
$330 - $600
Train operators
Deutsche Bahn
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Karlsruhe Hbf to Köln Hbf
Ave. Duration
2 h 5 min
Frequency
Every 2 hours
Estimated price
$60 - $95
Website
bahn.de
Train from Köln Hbf to Bruxelles-Nord
Ave. Duration
1 h 43 min
Frequency
Every 4 hours
Estimated price
$28 - $45
Website
bahn.de
Train from Karlsruhe Hbf to Mannheim Hbf
Ave. Duration
23 min
Frequency
Every 30 minutes
Estimated price
$20 - $29
Website
bahn.de
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
30 min
Frequency
Every 30 minutes
Estimated price
$22 - $35
Website
bahn.de
Train from Karlsruhe Hbf to Strasbourg
Ave. Duration
39 min
Frequency
3 times a day
Estimated price
$23 - $35
Website
bahn.de
Train from Karlsruhe Hbf to Basel SBB
Ave. Duration
1 h 47 min
Frequency
Hourly
Estimated price
$50 - $80
Website
bahn.de
TGV
Phone
0033 892 353535
Website
tgv.com
Train from Karlsruhe Hbf to Mannheim Hbf
Ave. Duration
24 min
Frequency
3 times a day
Estimated price
$17 - $22
Website
en.oui.sncf
2nd Class
$17 - $22
1st Class
$31 - $35
Train from Karlsruhe Hbf to Strasbourg
Ave. Duration
40 min
Frequency
5 times a day
Estimated price
$21 - $26
Website
en.oui.sncf
2nd Class
$21 - $26
1st Class
$38 - $40
Bus operators
FlixBus
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Karlsruhe to Brussels, Brussels-North station
Ave. Duration
7 h 35 min
Frequency
Twice daily
Estimated price
$30 - $50
Website
flixbus.co.uk
Bus from Karlsruhe to Stuttgart, Stuttgart Airport
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$4 - $8
Website
flixbus.co.uk
Eurolines DE
Phone
+49 6196 2078-501
Email
service@eurolines.de
Website
eurolines.de
Bus from Karlsruhe to Bruxelles - North
Ave. Duration
7 h 51 min
Frequency
3 times a week
Estimated price
$40 - $75
Website
eurolines.de
Low
$45
High
$51
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Karlsruhe to Strasbourg
Ave. Duration
1 h 15 min
Frequency
Twice a week
Estimated price
$40 - $60
Schedules at
eurolines.fr
Bus from Strasbourg to Brussels-North
Ave. Duration
7 h
Frequency
6 times a week
Estimated price
$55 - $100
Schedules at
eurolines.fr

Want to know more about travelling around Belgium

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Karlsruhe and Brussels is 355 km. The road distance is 490 km.

The cheapest way to get from Karlsruhe to Brussels is to bus which costs 25€ - 65€ and takes 7 h 35 min.

The quickest way to get from Karlsruhe to Brussels is to train and fly which takes 3 h 14 min and costs 100€ - 310€.

No, there is no direct train from Karlsruhe to Brussels. However, there are services departing from Karlsruhe Hbf and arriving at Bruxelles-Nord via Köln Hbf. The journey, including transfers, takes approximately 4 h 48 min.

Yes, there is a direct bus departing from Karlsruhe and arriving at Brussels, Brussels-North station. Services depart twice daily, and operate every day. The journey takes approximately 7 h 35 min.

It takes approximately 4 h 48 min to get from Karlsruhe to Brussels, including transfers.