Travel from Germany to Belgium is: Partially open. See details.

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There are 6 ways to get from Karlsruhe to Brussels by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train via Cologne  •  4h 57m

  1. Take the train from Karlsruhe Hbf to Koeln Hbf Ice / ...
  2. Take the train from Koeln Hbf to Brussel-Zuid / Bruxelles-Midi Ice / ...

€71 - €221

Cheapest option

Bus  •  7h 40m

  1. Take the bus from Karlsruhe central train station to Brussels-North train station N136 / ...

€16 - €22

4 alternative options

Train  •  5h 2m

  1. Take the train from Karlsruhe Hbf to Frankfurt(Main)Hbf Ice / ...
  2. Take the train from Frankfurt(Main)Hbf to Bruxelles-Nord Ice

€89 - €188

Drive  •  4h 25m

  1. Drive from Karlsruhe to Brussels 490.4 km

€50 - €80

Train to Frankfurt, fly  •  3h 25m

  1. Take the train from Karlsruhe Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Brussels (BRU) FRA - BRU

€83 - €231

Train to Stuttgart, fly  •  4h 59m

  1. Take the train from Karlsruhe Hbf to Stuttgart Hbf
  2. Fly from Stuttgart (STR) to Brussels (BRU) STR - BRU

€60 - €281

Karlsruhe to Brussels by train

The train journey time between Karlsruhe and Brussels is around 5h 5m and covers a distance of around 519 km. The fastest train normally takes 4h 34m. Operated by Deutsche Bahn Intercity-Express, Swiss Railways (SBB/CFF/FFS), Deutsche Bahn Intercity and others, the Karlsruhe to Brussels train service departs from Karlsruhe Hbf and arrives in Brussel-Zuid / Bruxelles-Midi. Typically 53 trains run weekly, although weekend and holiday schedules can vary so check in advance.

Train route overview

Average train time:
5h 5m
Fastest train time:
4h 34m
Train distance:
519 km
Trains per week:
53
Cheapest price:
€96
Carbon emissions:
27 kg CO2

First and last trains

First train departs at:
01:30
Last train departs at:
19:00

The schedules shown below are for the next available departures.

Karlsruhe to Brussels train schedules

Germany → Belgium
Partially open

Travel safe during COVID-19

International entry into Belgium from Germany

  • Entry is partially open for citizens and permanent residents of Germany
Show more details
Allowed for: Citizens and permanent residents of Belgium, as well as residents from EU Schengen Area (EU countries, Iceland, Liechtenstein, Norway, and Switzerland), Albania, Andorra, Armenia, Australia, Azerbaijan, Bosnia and Herzegovina, Brunei, Canada, Cyprus, Hong Kong, Israel, Japan, Jordan, Kosovo, Lebanon, Macau, Moldova, Monaco, Montenegro, New Zealand, North Macedonia, Qatar, Rwanda, San Marino, Saudi Arabia, Serbia, Singapore, South Korea, Taiwan, Thailand, United States and Vatican

Restricted for: Foreign nationals from outside EU Schengen Area with the above exceptions. Argentina, Bolivia, Botswana, Brazil, Chile, Colombia, Eswatini, India, Lesotho, Malawi, Mexico, Mozambique, Namibia, Paraguay, Peru, South Africa, Suriname, Trinidad and Tobago, Uruguay, Zambia and Zimbabwe are also restricted

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Conditions of entry into Belgium from Germany

  • Negative COVID-19 test issued at most 3 days before arrival and 10 day mandatory self quarantine
  • A negative result for COVID-19 is a condition for subsequent release from quarantine. It is tested in quarantine on days 1 and 7
  • Travellers with the Digital Green Certificate are exempt from the quarantine. Digital Green Certificate is proof that a person has been vaccinated against COVID-19, received a negative test result, or recovered from COVID-19
  • Travellers who have recovered from COVID-19 in the last 6 months are exempt from providing a negative COVID-19 test (certificate needed)
  • Travellers with a certificate of vaccination are exempt from providing a negative COVID-19 test
This applies to arrivals from Germany
  • Passenger Locator Form (PLF) required
  • Negative COVID-19 test issued at most 3 days before arrival
This applies to arrivals from all countries, with no exceptions
Show more details
  • Negative COVID-19 test issued at most 3 days before arrival and 10 day mandatory self quarantine
  • A negative result for COVID-19 is a condition for subsequent release from quarantine. It is tested in quarantine on days 1 and 7
This doesn't apply to arrivals from the EU Schengen Area with the exception of Cyprus, Luxembourg, Netherlands, Portugal and Spain. This also doesn't apply to arrivals from Albania, Armenia, Australia, Azerbaijan, Bosnia and Herzegovina, Brunei, Canada, Hong Kong, Israel, Japan, Jordan, Kosovo, Lebanon, Macau, Moldova, Montenegro, New Zealand, North Macedonia, Qatar, Rwanda, Saudi Arabia, Serbia, Singapore, South Korea, Taiwan, Thailand and United States
  • Passenger Locator Form (PLF) required
  • Negative COVID-19 test issued at most 3 days before arrival
This applies to arrivals from all countries, with no exceptions
  • Travellers with the Digital Green Certificate are exempt from the quarantine. Digital Green Certificate is proof that a person has been vaccinated against COVID-19, received a negative test result, or recovered from COVID-19
This applies to arrivals from EU Schengen Area
  • Travellers who have recovered from COVID-19 in the last 6 months are exempt from providing a negative COVID-19 test (certificate needed)
  • Travellers with a certificate of vaccination are exempt from providing a negative COVID-19 test
This doesn’t apply to citizens and permanent residents of Argentina, Bahrain, Bangladesh, Bolivia, Botswana, Brazil, Chile, Colombia, Democratic Republic of the Congo, Eswatini, Georgia, India, Indonesia, Lesotho, Malawi, Mexico, Mozambique, Namibia, Nepal, Paraguay, Peru, Russia, South Africa, Suriname, Trinidad and Tobago, Tunisia, Uganda, United Kingdom, Uruguay, Zambia and Zimbabwe

Show less

Rules to follow in Belgium

1.5m

Mandatory

Mandatory

Considerations leaving from Germany

The official advice is to avoid non-essential international travel to high risk countries

Frequently Asked Questions


Yes, but conditions apply when entering Belgium from Germany.

Explore options for future travel

Domestic travel is not restricted, but some conditions may apply

  • Face masks are mandatory
  • There is a social distancing requirement of 1.5 metres
  • Further restrictions may be implemented at short notice

Explore travel options

The national COVID-19 helpline number in Brussels is 800 14689.

Wearing a face mask on public transport in Brussels is mandatory.

The social distance requirement in Brussels is 1.5 metres.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800 14689.

No, but conditions apply when returning to Germany from Belgium.

See options for return travel.

Last updated: 18 Jul 2021
Exceptions may apply, for full details: European Union.

We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.

Questions & Answers

The cheapest way to get from Karlsruhe to Brussels is to bus which costs €16 - €22 and takes 7h 40m.

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The quickest way to get from Karlsruhe to Brussels is to train and fly which costs €80 - €240 and takes 3h 25m.

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Yes, there is a direct bus departing from Karlsruhe central train station station and arriving at Brussels-North train station station. Services depart six times a week, and operate every day. The journey takes approximately 7h 40m.

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No, there is no direct train from Karlsruhe to Brussels. However, there are services departing from Karlsruhe Hbf and arriving at Brussel-Zuid / Bruxelles-Midi via Koeln Hbf. The journey, including transfers, takes approximately 4h 57m.

More details

The distance between Karlsruhe and Brussels is 355 km. The road distance is 490.4 km.

Get driving directions

The best way to get from Karlsruhe to Brussels without a car is to train via Cologne which takes 4h 57m and costs €70 - €230.

More details

It takes approximately 4h 57m to get from Karlsruhe to Brussels, including transfers.

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Karlsruhe to Brussels bus services, operated by FlixBus, depart from Karlsruhe central train station.

More details

Karlsruhe to Brussels train services, operated by Deutsche Bahn Intercity-Express, depart from Karlsruhe Hbf station.

More details

The best way to get from Karlsruhe to Brussels is to train via Cologne which takes 4h 57m and costs €70 - €230. Alternatively, you can bus, which costs €16 - €22 and takes 7h 40m.

Mode details

Map of how to get from Karlsruhe to Brussels.
Launch map view
  • Distance: 355.1 km
  • Duration: 4h 57m

What companies run services between Karlsruhe, Germany and Brussels, Belgium?

You can take a train from Karlsruhe to Brussels via Koeln Hbf in around 4h 57m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Brussels-North train station 6 times a week. Tickets cost €25 - €31 and the journey takes 7h 40m. Union Ivkoni also services this route twice a week.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Brussels
Ave. Duration
57 min
When
Every day
Estimated price
€70 - €380
Flights from Stuttgart to Brussels via Frankfurt
Ave. Duration
3h 2m
When
Tuesday, Thursday, Friday, Saturday and Sunday
Estimated price
€75 - €380
Brussels Airlines
Website
brusselsairlines.com
Flights from Frankfurt to Brussels
Ave. Duration
57 min
When
Every day
Estimated price
€70 - €380
Flights from Stuttgart to Brussels
Ave. Duration
1h 10m
When
Monday and Tuesday
Estimated price
€40 - €210
Eurowings
Website
eurowings.com
Flights from Stuttgart to Brussels
Ave. Duration
1h 10m
When
Monday and Tuesday
Estimated price
€40 - €210
Train operators
Deutsche Bahn Intercity-Express

German rail company Deutsche Bahn is known for its efficient and comfortable service. It offers many different types of rail transportation, including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare (bookings usually open 6 months in advance for domestic tickets).

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Karlsruhe Hbf to Koeln Hbf
Ave. Duration
2h 5m
Frequency
Every 2 hours
Estimated price
€55 - €80
Website
Deutsche Bahn
Train from Koeln Hbf to Brussel-Zuid / Bruxelles-Midi
Ave. Duration
1h 52m
Frequency
Every 4 hours
Estimated price
€40 - €60
Website
Deutsche Bahn
Train from Karlsruhe Hbf to Frankfurt(Main)Hbf
Ave. Duration
1h 5m
Frequency
Hourly
Estimated price
€30 - €45
Website
Deutsche Bahn
Train from Frankfurt(Main)Hbf to Bruxelles-Nord
Ave. Duration
2h 57m
Frequency
Every 4 hours
Estimated price
€70 - €100
Website
Deutsche Bahn
Train from Karlsruhe Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
1h 6m
Frequency
Every 2 hours
Estimated price
€30 - €45
Website
Deutsche Bahn
Train from Karlsruhe Hbf to Stuttgart Hbf
Ave. Duration
36 min
Frequency
4 times a day
Estimated price
€22 - €35
Website
Deutsche Bahn
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs.

Contact Details
Phone
+41 51 220 11 11
Website
sbb.ch
Train from Karlsruhe Hbf to Koeln Hbf
Ave. Duration
2h 53m
Frequency
3 times a day
Estimated price
€80 - €150
Website
Swiss Railways (SBB/CFF/FFS)
Train from Karlsruhe Hbf to Frankfurt(Main)Hbf
Ave. Duration
1h 14m
Frequency
Once daily
Estimated price
€40 - €75
Website
Swiss Railways (SBB/CFF/FFS)
Deutsche Bahn Intercity

Deutsche Bahn’s high-speed InterCity (IC) trains connect cities within Germany. They’re a popular way to travel as they’re faster than Deutsche Bahn’s regional trains and offer a frequent, fast service. All IC trains have first and second class carriages, power sockets and toilets, and most have a bistro cafe or restaurant. Tickets can be booked up to 180 days in advance of travel.

Contact Details
Phone
+49 30 2970
Website
bahn.com
Train from Karlsruhe Hbf to Koeln Hbf
Ave. Duration
3h 17m
Frequency
Twice daily
Estimated price
€65 - €95
Website
reiseauskunft.bahn.de
Train from Karlsruhe Hbf to Frankfurt(Main)Hbf
Ave. Duration
1h 30m
Frequency
Twice daily
Estimated price
€45 - €65
Website
reiseauskunft.bahn.de
Train from Karlsruhe Hbf to Stuttgart Hbf
Ave. Duration
56 min
Frequency
Hourly
Estimated price
€40 - €55
Website
reiseauskunft.bahn.de
Deutsche Bahn Eurocity

Deutsche Bahn’s EuroCity (EC) trains connect German cities to major cities in neighbouring European countries, and are operated in conjunction with their national train company. All EC trains offer First and Standard class; cars are air-conditioned and food and drinks are available onboard. Tickets can be booked up to 180 days in advance of travel. Seat reservations are not compulsory but are recommended for popular routes.

Contact Details
Phone
+49 30 2970
Website
bahn.com
Train from Karlsruhe Hbf to Koeln Hbf
Ave. Duration
2h 53m
Frequency
5 times a week
Estimated price
€30 - €45
Website
reiseauskunft.bahn.de
Train from Karlsruhe Hbf to Frankfurt(Main)Hbf
Ave. Duration
1h 15m
Frequency
Once a week
Estimated price
€18 - €26
Website
reiseauskunft.bahn.de
Thalys
Phone
+32 70 66 77 88
Website
thalys.com
Train from Koeln Hbf to Brussel-Zuid / Bruxelles-Midi
Ave. Duration
2h 2m
Frequency
4 times a day
Estimated price
€65 - €130
Website
Thalys
Standard
€65 - €90
Comfort
€75 - €100
Premium
€90 - €130
TGV inOui

France’s high-speed TGV train network runs at speeds of up to 320km/h connecting major cities across France and into neighbouring countries. All TGV tickets include a seat reservation; seating is 1+2 in 1st class, 2+2 in 2nd class. Popular routes include Paris to Marseille and Paris to Strasbourg. Most TGVs have a cafe area, power points at each seat and WiFi.

Contact Details
Phone
0033 892 353535
Website
en.oui.sncf
Train from Karlsruhe Hbf to Frankfurt(Main)Hbf
Ave. Duration
1h 4m
Frequency
3 times a day
Estimated price
€30 - €45
Website
Oui.SNCF
2nd Class
€35 - €45
1st Class
€30 - €40
Train from Karlsruhe Hbf to Stuttgart Hbf
Ave. Duration
35 min
Frequency
4 times a day
Estimated price
€23 - €35
Website
Oui.SNCF
2nd Class
€29 - €34
1st Class
€23 - €28
Deutsche Bahn Regional

Deutsche Bahn’s regional network is made up of IRE (Interregio-Express), RE (Regional-Express), RB (Regionalbahn) and S-Bahn trains. Ticket prices are fixed and there’s no seat reservations – just turn up, buy a ticket and jump on the next train. All regional trains depart regularly and connect to local and long-distance services.

Contact Details
Phone
+49 30 2970
Website
bahn.com
Train from Karlsruhe Hbf to Frankfurt(Main)Hbf
Ave. Duration
2h 15m
Frequency
3 times a day
Estimated price
€22 - €35
Website
reiseauskunft.bahn.de
Trenitalia Eurocity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Karlsruhe Hbf to Frankfurt(Main)Hbf
Ave. Duration
1h 15m
Frequency
Once daily
Estimated price
€35 - €90
Website
Trenitalia Eurocity
2nd Class
€35 - €50
1st Class
€65 - €90
Go Ahead BW
Phone
+49 711 400 534 44
Website
go-ahead-bw.de
Train from Karlsruhe Hbf to Stuttgart Hbf
Ave. Duration
53 min
Frequency
Hourly
Website
Go Ahead BW
Verkehrs- und Tarifverbund Stuttgart (VVS)
Phone
0711 19449
Website
vvs.de
Train from Karlsruhe Hauptbahnhof to Stuttgart Hauptbahnhof
Ave. Duration
55 min
Frequency
Hourly
Estimated price
€9 - €13
Website
Verkehrs- und Tarifverbund Stuttgart (VVS)
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Karlsruhe central train station to Brussels-North train station
Ave. Duration
7h 40m
Frequency
6 times a week
Estimated price
€25 - €31
Website
flixbus.co.uk
Union Ivkoni
Phone
02/989 0000
Website
union-ivkoni.com
Bus from Karlsruhe to Brussels
Ave. Duration
9h 35m
Frequency
Twice a week
Estimated price
€16 - €22
Schedules at
union-ivkoni.com

Want to know more about travelling around Belgium

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Frankfurt Airport to Brussels Airport is the direct flight which takes 55 min.

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Karlsruhe to Brussels bus services, operated by FlixBus, arrive at Brussels-North train station.

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Karlsruhe to Brussels train services, operated by Deutsche Bahn Intercity-Express, arrive at Brussel-Zuid / Bruxelles-Midi station.

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Yes, the driving distance between Karlsruhe to Brussels is 490 km. It takes approximately 4h 25m to drive from Karlsruhe to Brussels.

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Brussels Airlines and Lufthansa offer flights from Frankfurt Airport to Brussels Airport.

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Book your Karlsruhe to Brussels train tickets online with Omio.

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Book your Karlsruhe to Brussels bus tickets online with Omio and FlixBus.

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There are 429+ hotels available in Brussels. Prices start at €75 per night.

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