Travel from Karlsruhe to Brussels

Bus or train from Karlsruhe to Brussels?

German Railways (DB) operates a train from Karlsruhe to Brussels every 3 hours. Tickets cost $65 - $95 and the journey takes 2 h 5 min. Thalys also services this route every 3 hours. Alternatively, Eurolines DE operates a bus from Karlsruhe to Brussels once daily. Tickets cost $45 - $80 and the journey takes 8 h 56 min. FlixBus also services this route 6 times a week.

Travel Guides

Want to know more about Flixbus?Rome2rio’s guide has all the details
Need to know: EurostarRome2rio’s guide to travelling between London, Brussels and Paris

How to get from Karlsruhe to Brussels

From Karlsruhe Hbf train to Köln Hbf then train to Bruxelles-Midi. 4 h 55 min 144€. From Karlsruhe Hbf bus to Brussels North. 8 h 56 min 44€. From Karlsruhe Hbf train to Neustadt(Weinstr)Hbf, train to Trier Hbf, train to Luxembourg, then train to Bruxelles-Central. 9 h 1 min 84€. From Karlsruhe bus to Strasbourg then bus to Brussels-North. 9 h 15 min 105€. From Karlsruhe drive to Brussels. 4 h 28 min 64€. From Karlsruhe Hbf train to Strasbourg, train to Strasbourg airport, fly to Brussels airport, then train to Brussels. 3 h 6 min 164€. From Karlsruhe Hbf train to Stuttgart Hbf (tief), train to Stuttgart airport, fly to Brussels airport, then train to Brussels. 4 h 54 min 127€. From Karlsruhe Hbf train to Mannheim Hbf, train to Frankfurt airport, fly to Brussels airport, then train to Brussels. 5 h 5 min 151€. From Karlsruhe Hbf train to Basel, Bahnhof SBB, line 50 bus to Basel airport, fly to Brussels airport, then train to Brussels. 5 h 41 min 159€. From Karlsruhe Hbf train to Strasbourg, train to Strasbourg airport, fly to Lille Lesquin airport, shuttle to Lille Europe Eurostar, then train to Brussels. 5 h 36 min 212€.
Close Print Itinerary
  1. Here are 10 options to get from
    Karlsruhe to Brussels:

    1. Trip:
      1 Train
      • One-Way approx: USD $132 - $190
      • Duration: 4 h 55 min
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      • Trip:
        1 Train
        • One-Way approx: USD $132 - $190
        • Duration: 4 h 55 min
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    2. Trip:
      2 Bus Eurolines DE
      • One-Way approx: USD $30 - $80
      • Duration: 8 h 56 min
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      • Trip:
        2 Bus Eurolines DE
        • One-Way approx: USD $30 - $80
        • Duration: 8 h 56 min
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    3. Trip:
      3 Train via Luxembourg
      • One-Way approx: USD $81 - $126
      • Duration: 9 h 1 min
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      • Trip:
        3 Train via Luxembourg
        • One-Way approx: USD $81 - $126
        • Duration: 9 h 1 min
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    4. Trip:
      4 Bus Eurolines FR
      • One-Way approx: USD $98 - $160
      • Duration: 9 h 15 min
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      • Trip:
        4 Bus Eurolines FR
        • One-Way approx: USD $98 - $160
        • Duration: 9 h 15 min
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    5. Trip:
      5 Drive
      • One-Way approx: USD $60 - $95
      • Duration: 4 h 28 min
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      • Trip:
        5 Drive
        • One-Way approx: USD $60 - $95
        • Duration: 4 h 28 min
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    6. Trip:
      6 Train to Strasbourg, fly to Brussels
      • One-Way approx: USD $122 - $354
      • Duration: 3 h 6 min
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      • Trip:
        6 Train to Strasbourg, fly to Brussels
        • One-Way approx: USD $122 - $354
        • Duration: 3 h 6 min
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    7. Trip:
      7 Train to Stuttgart, fly to Brussels
      • One-Way approx: USD $102 - $292
      • Duration: 4 h 54 min
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      • Trip:
        7 Train to Stuttgart, fly to Brussels
        • One-Way approx: USD $102 - $292
        • Duration: 4 h 54 min
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    8. Trip:
      8 Train, train to Frankfurt, fly to Brussels
      • One-Way approx: USD $129 - $337
      • Duration: 5 h 5 min
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      • Trip:
        8 Train, train to Frankfurt, fly to Brussels
        • One-Way approx: USD $129 - $337
        • Duration: 5 h 5 min
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    9. Trip:
      9 Train to Basel, fly to Brussels
      • One-Way approx: USD $112 - $353
      • Duration: 5 h 41 min
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      • Trip:
        9 Train to Basel, fly to Brussels
        • One-Way approx: USD $112 - $353
        • Duration: 5 h 41 min
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    10. Trip:
      10 Train to Strasbourg, fly to Lille Lesquin, train
      • One-Way approx: USD $132 - $472
      • Duration: 5 h 36 min
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      • Trip:
        10 Train to Strasbourg, fly to Lille Lesquin, train
        • One-Way approx: USD $132 - $472
        • Duration: 5 h 36 min
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