There are 8 ways to get from Karlsruhe to Brussels by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  4 h 48 min

  1. Take the train from Karlsruhe Hbf to Köln Hbf Ice / ...
  2. Take the train from Köln Hauptbahnhof to Brusel Nord Ice

$109 - $161

Cheapest option

Bus FlixBus  •  7 h 35 min

  1. Take the bus from Karlsruhe to Saarbrücken 236 / ...
  2. Take the bus from Saarbrücken to Brussels, Brussels-North station 299 / ...

$27 - $44

6 alternative options

Bus Eurolines DE  •  9 h 3 min

  1. Take the bus from Karlsruhe Hbf to Brussels North

$55 - $75

Drive  •  4 h 28 min

  1. Drive from Karlsruhe to Brussels 305.9 miles

$60 - $95

Train, train to Frankfurt, fly  •  3 h 27 min

  1. Take the train from Karlsruhe Hbf to Mannheim Hbf
  2. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  3. Fly from Frankfurt (FRA) to Brussels (BRU) FRA - BRU

$124 - $335

Train to Stuttgart, fly  •  5 h

  1. Take the train from Karlsruhe Hbf to Stuttgart Hbf
  2. Fly from Stuttgart (STR) to Brussels (BRU) STR - BRU

$97 - $289

Train to Strasbourg, fly  •  4 h 22 min

  1. Take the train from Karlsruhe Hbf to Strasbourg
  2. Fly from Strasbourg (SXB) to Brussels (BRU) SXB - BRU

$113 - $359

Train to Basel, fly  •  5 h 32 min

  1. Take the train from Karlsruhe Hbf to Basel SBB
  2. Fly from Basel (BSL) to Brussels (BRU) BSL - BRU

$109 - $347

Questions & Answers

The cheapest way to get from Karlsruhe to Brussels is to bus which costs 22€ - 40€ and takes 7 h 35 min.

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The quickest way to get from Karlsruhe to Brussels is to train and fly which costs 100€ - 290€ and takes 3 h 27 min.

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Yes, there is a direct bus departing from Karlsruhe Hbf and arriving at Brussels North. Services depart once daily, and operate Monday, Thursday and Friday. The journey takes approximately 9 h 3 min.

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No, there is no direct train from Karlsruhe to Brussels. However, there are services departing from Karlsruhe Hbf and arriving at Brusel Nord via Köln Hauptbahnhof. The journey, including transfers, takes approximately 4 h 48 min.

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The distance between Karlsruhe and Brussels is 355 km. The road distance is 489.5 km.

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The best way to get from Karlsruhe to Brussels without a car is to train which takes 4 h 48 min and costs 90€ - 140€.

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It takes approximately 4 h 48 min to get from Karlsruhe to Brussels, including transfers.

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Karlsruhe to Brussels bus services, operated by FlixBus, depart from Karlsruhe station.

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Karlsruhe to Brussels train services, operated by Deutsche Bahn, depart from Karlsruhe Hbf station.

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The best way to get from Karlsruhe to Brussels is to train which takes 4 h 48 min and costs 90€ - 140€. Alternatively, you can bus, which costs 22€ - 40€ and takes 7 h 35 min.

Mode details

Map of how to get from Karlsruhe to Brussels.
Launch map view
  • Distance: 222 miles
  • Duration: 4 h 48 min

What companies run services between Karlsruhe, Germany and Brussels, Belgium?

You can take a train from Karlsruhe to Brussels via Köln Hbf and Köln Hauptbahnhof in around 4 h 48 min. Alternatively, you can take a bus from Karlsruhe to Brussels via Saarbrücken in around 7 h 35 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Brussels
Ave. Duration
55 min
When
Every day
Estimated price
$100 - $380
Flights from Stuttgart to Brussels via Frankfurt
Ave. Duration
3 h 18 min
When
Every day
Estimated price
$200 - $750
Flights from Stuttgart to Brussels via Munich
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$200 - $750
Flights from Basel to Brussels via Frankfurt
Ave. Duration
2 h 53 min
When
Every day
Estimated price
$180 - $800
Brussels Airlines
Website
brusselsairlines.com
Flights from Frankfurt to Brussels
Ave. Duration
55 min
When
Every day
Estimated price
$100 - $380
Flights from Stuttgart to Brussels
Ave. Duration
1 h 20 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$60 - $460
Flights from Strasbourg to Brussels
Ave. Duration
1 h
When
Monday to Friday
Estimated price
$85 - $650
Flights from Basel to Brussels
Ave. Duration
1 h 7 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$70 - $1,000
Swiss
Website
swiss.com
Flights from Stuttgart to Brussels via Zurich
Ave. Duration
3 h 8 min
When
Every day
Estimated price
$210 - $750
Flights from Basel to Brussels
Ave. Duration
1 h 7 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$70 - $1,000
Eurowings
Website
eurowings.com
Flights from Stuttgart to Brussels
Ave. Duration
1 h 20 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$60 - $460
KLM
Website
klm.com
Flights from Stuttgart to Brussels via Amsterdam
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$150 - $490
easyJet
Website
easyjet.com
Flights from Basel to Brussels
Ave. Duration
1 h 10 min
When
Monday, Thursday, Friday and Sunday
Estimated price
$45 - $290
Train operators
Deutsche Bahn

Deutsche Bahn is the German railway company, and the largest railway operator and infrastructure owner in Europe. Based in Berlin, Deutsche Bahn was founded in 1994, and offers many different types of rail transportation including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare.

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Karlsruhe Hbf to Köln Hbf
Ave. Duration
2 h 5 min
Frequency
Every 2 hours
Estimated price
$60 - $95
Website
bahn.de
Train from Köln Hauptbahnhof to Brusel Nord
Ave. Duration
1 h 43 min
Frequency
Every 4 hours
Estimated price
$45 - $70
Website
bahn.de
Train from Karlsruhe Hbf to Mannheim Hbf
Ave. Duration
23 min
Frequency
Hourly
Estimated price
$20 - $29
Website
bahn.de
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
30 min
Frequency
Hourly
Estimated price
$22 - $35
Website
bahn.de
Train from Karlsruhe Hbf to Stuttgart Hbf
Ave. Duration
44 min
Frequency
Hourly
Estimated price
$23 - $35
Website
bahn.de
Train from Karlsruhe Hbf to Strasbourg
Ave. Duration
41 min
Frequency
4 times a day
Estimated price
$23 - $35
Website
bahn.de
Train from Karlsruhe Hbf to Basel SBB
Ave. Duration
1 h 47 min
Frequency
Hourly
Estimated price
$50 - $85
Website
bahn.de
TGV
Phone
0033 892 353535
Website
sncf.com
Train from Karlsruhe Hbf to Mannheim Hbf
Ave. Duration
23 min
Frequency
Once daily
Estimated price
$17 - $22
Website
en.oui.sncf
2nd Class
$17 - $22
1st Class
$31 - $35
Train from Karlsruhe Hbf to Stuttgart Hbf
Ave. Duration
36 min
Frequency
4 times a day
Estimated price
$21 - $26
Website
en.oui.sncf
2nd Class
$21 - $26
1st Class
$37 - $40
Train from Karlsruhe Hbf to Strasbourg
Ave. Duration
41 min
Frequency
5 times a day
Estimated price
$21 - $26
Website
en.oui.sncf
2nd Class
$21 - $26
1st Class
$38 - $40
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Karlsruhe to Saarbrücken
Ave. Duration
2 h 15 min
Frequency
3 times a day
Estimated price
$8 - $15
Website
flixbus.co.uk
Bus from Saarbrücken to Brussels, Brussels-North station
Ave. Duration
4 h 20 min
Frequency
4 times a day
Estimated price
$18 - $30
Website
flixbus.co.uk
Eurolines DE
Phone
+49 6196 2078-501
Email
service@eurolines.de
Website
eurolines.de
Bus from Karlsruhe Hbf to Brussels North
Ave. Duration
9 h 3 min
Frequency
Once daily
Estimated price
$55 - $75
Website
eurolines.de

Want to know more about travelling around Belgium

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More Questions & Answers

The quickest flight from Frankfurt Airport to Brussels Airport is the direct flight which takes 55 min.

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Karlsruhe to Brussels bus services, operated by FlixBus, arrive at Brussels, Brussels-North station.

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Karlsruhe to Brussels train services, operated by Deutsche Bahn, arrive at Brusel Nord station.

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Yes, the driving distance between Karlsruhe to Brussels is 490 km. It takes approximately 4 h 28 min to drive from Karlsruhe to Brussels.

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Lufthansa offers flights from Frankfurt Airport to Brussels Airport.

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Book your Karlsruhe to Brussels bus tickets online with FlixBus and FlixBus.

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There are 954+ hotels available in Brussels. Prices start at $70 USD per night.

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