Rome2Rio

How to get fromKarlsruhe to Assisiby train (Trenitalia), bus, train, night train, car or plane

Find Transport to Assisi

See all options

There are 13 ways to get from Karlsruhe to Assisi by train (Trenitalia), bus, train, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain20 / ...
    2. Take the train from Basel SBB to ChiassotrainEc
    3. Take the train from Chiasso to Milano Porta GaribalditrainS11
    4. Take the train from Milano P.Garibaldi to PerugiatrainFr
    14h 27m
    €118–361

  2. Bus via Milan

    cheapest
    1. Take the bus from Karlsruhe Central Bus Station to Milanbus
    2. Take the bus from Milan to Florence Villa Constanza Bus Stationbus
    3. Take the bus from Florence Villa Constanza Bus Station to Assisibus529
    20h
    €55–164

  3. Bus

    1. Take the bus from Karlsruhe central train station to Florence Villa Constanza Bus StationbusN77
    2. Take the bus from Florence Villa Constanza Bus Station to Assisibus529
    17h 50m
    €78–108

  4. Train, night train

    1. Take the train from Karlsruhe Hbf to Stuttgart HbftrainRe
    2. Take the night train from Stuttgart Hbf to Venezia MestrenighttrainNj
    3. Take the train from Venezia Mestre to FolignotrainIc
    22h 39m
    €104–372

  5. Drive 995.8 km

    1. Drive from Karlsruhe to Assisicar995.8 km
    9h 40m
    €157–226

  6. Train via Zurich

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain20 / ...
    2. Take the train from Basel SBB to Zürich HBtrainIce / ...
    3. Take the train from Zürich HB to Milano LambratetrainEc
    4. Take the train from Milano Lambrate to AssisitrainIc
    15h 20m
    €157–331

  7. Train to Frankfurt, fly to Florence Peretola Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain
    2. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)planeFRA - FLR
    3. Take the train from Firenze S.M.N. to Assisitrain
    10h 4m
    €130–387

  8. Train to Stuttgart Airport, fly to Fiumicino International Airport, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
    2. Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)planeSTR - FCO
    3. Take the train from Roma Termini to Folignotrain
    10h 24m
    €98–293

  9. Train to Frankfurt, fly to Fiumicino International Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain
    2. Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)planeFRA - FCO
    3. Take the train from Roma Termini to Folignotrain
    10h 29m
    €76–299

  10. Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain
    2. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)planeFRA - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train
    4. Take the train from Firenze S.M.N. to Assisitrain
    10h 28m
    €141–444

  11. Train, train to Zurich Airport, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
    2. Take the train from Basel SBB to Zürich HBtrain
    3. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)planeZRH - FLR
    4. Take the train from Firenze S.M.N. to Assisitrain
    11h 34m
    €153–475

  12. Train, train to Zurich Airport, fly to Fiumicino International Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
    2. Take the train from Basel SBB to Zürich HBtrain
    3. Fly from Zurich Airport (ZRH) to Fiumicino International Airport (FCO)planeZRH - FCO
    4. Take the train from Roma Termini to Folignotrain
    12h 5m
    €109–387

  13. Train, train to Zurich Airport, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
    2. Take the train from Basel SBB to Zürich HBtrain
    3. Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)planeZRH - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train
    5. Take the train from Firenze S.M.N. to Assisitrain
    12h 9m
    €159–522

Karlsruhe to Assisi by train and bus

Calendar6Weekly Services
Duration14h 27mAverage Duration
Ticket€118Cheapest Price
See schedules

Questions & Answers

What companies run services between Karlsruhe, Germany and Assisi, Italy?

You can take a train from Karlsruhe Hauptbahnhof to P.za Matteotti Assisi via Basel SBB, Chiasso, Milano P.Garibaldi, Perugia, and Fontivegge - Perugia in around 14h 27m. Alternatively, you can take a bus from Karlsruhe central train station to Assisi via Florence Villa Constanza Bus Station in around 17h 50m.

Transport is disrupted due to the Russia-Ukraine war. Read more

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

More Questions & Answers

Where to next?

Trips from Karlsruhe

Trips to Assisi

Popular routes