There are 8 ways to get from Kansas City to Knoxville by plane, bus, car or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville  •  6 h 25 min

  1. Fly from Kansas City (MCI) to Knoxville (TYS) MCI - TYS

$276 - $1,172

Cheapest option

Bus  •  14 h 18 min

  1. Take the bus from Kansas City, Mo to St Louis, Mo
  2. Take the bus from St Louis, Mo to Nashville, Tn
  3. Take the bus from Nashville, Tn to Knoxville, Tn

$87 - $208

6 alternative options

Fly to Chattanooga, bus  •  8 h 17 min

  1. Fly from Kansas City (MCI) to Chattanooga (CHA) MCI - CHA
  2. Take the bus from Chattanooga, Tn to Knoxville, Tn

$198 - $942

Fly to Atlanta, bus  •  9 h 24 min

  1. Fly from Kansas City (MCI) to Atlanta (ATL) MCI - ATL
  2. Take the bus from Atlanta, Ga to Knoxville, Tn

$140 - $390

Fly to Asheville, drive  •  8 h 16 min

  1. Fly from Kansas City (MCI) to Asheville (AVL) MCI - AVL
  2. Drive from Asheville to Knoxville

$244 - $1,120

Train, bus  •  16 h 25 min

  1. Take the train from Kansas City Amtrak to St. Louis Gateway Station Amtrak
  2. Take the bus from St Louis, Mo to Nashville, Tn
  3. Take the bus from Nashville, Tn to Knoxville, Tn

$111 - $269

Bus via Little Rock, Ar  •  21 h 26 min

  1. Take the bus from Kansas City, MO to Little Rock, AR 121
  2. Take the bus from Little Rock, Ar to Knoxville, Tn 1508 / ...

$123 - $229

Drive  •  12 h 7 min

  1. Drive from Kansas City to Knoxville 735.7 miles

$70 - $110

Questions & Answers

The cheapest way to get from Kansas City to Knoxville is to drive which costs $70 - $110 and takes 12 h 7 min.

More details

The quickest way to get from Kansas City to Knoxville is to fly which costs $270 - $1,200 and takes 6 h 25 min.

More details

The distance between Kansas City and Knoxville is 626 miles. The road distance is 735.7 miles.

Get driving directions

It takes approximately 6 h 25 min to get from Kansas City to Knoxville, including transfers.

More details

No, there is no direct bus from Kansas City to Knoxville. However, there are services departing from Kansas City, Mo and arriving at Knoxville, Tn via St Louis, Mo and Nashville, Tn. The journey, including transfers, takes approximately 14 h 18 min.

More details

What companies run services between Kansas City, MO, USA and Knoxville, TN, USA?

Delta, American Airlines and United Airlines fly from Kansas City to Knoxville hourly. Alternatively, you can take a bus from Kansas City to Knoxville via St Louis, Mo and Nashville, Tn in around 14 h 18 min.

Airlines
Delta
Website
delta.com
Flights from Kansas City to Knoxville via Atlanta
Ave. Duration
4 h 33 min
When
Every day
Estimated price
$220 - $1,100
Flights from Kansas City to Knoxville via Detroit
Ave. Duration
4 h 37 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,200
Flights from Kansas City to Knoxville via Minneapolis
Ave. Duration
5 h 32 min
When
Every day
Estimated price
$250 - $1,200
Flights from Kansas City to Chattanooga via Atlanta
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$180 - $900
Flights from Kansas City to Chattanooga via New York La Guardia
Ave. Duration
6 h 22 min
When
Saturday
Estimated price
$260 - $1,100
Flights from Kansas City to Chattanooga via Detroit
Ave. Duration
7 h 3 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,000
Flights from Kansas City to Atlanta
Ave. Duration
2 h 3 min
When
Every day
Estimated price
$170 - $600
Flights from Kansas City to Asheville via Atlanta
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$230 - $1,100
American Airlines
Website
aa.com
Flights from Kansas City to Knoxville via Chicago O'Hare
Ave. Duration
4 h 12 min
When
Every day
Estimated price
$240 - $1,100
Flights from Kansas City to Knoxville via Charlotte
Ave. Duration
4 h 34 min
When
Every day
Estimated price
$250 - $1,200
Flights from Kansas City to Knoxville via Dallas/Ft.Worth
Ave. Duration
5 h 19 min
When
Every day
Estimated price
$270 - $1,200
Flights from Kansas City to Knoxville via Philadelphia
Ave. Duration
5 h 40 min
When
Saturday
Estimated price
$310 - $1,300
Flights from Kansas City to Chattanooga via Chicago O'Hare
Ave. Duration
4 h 22 min
When
Every day
Estimated price
$200 - $950
Flights from Kansas City to Chattanooga via Charlotte
Ave. Duration
4 h 56 min
When
Every day
Estimated price
$220 - $950
Flights from Kansas City to Chattanooga via Dallas/Ft.Worth
Ave. Duration
5 h 2 min
When
Every day
Estimated price
$220 - $1,000
Flights from Kansas City to Asheville via Charlotte
Ave. Duration
5 h 7 min
When
Every day
Estimated price
$250 - $1,200
Flights from Kansas City to Asheville via Dallas/Ft.Worth
Ave. Duration
5 h 38 min
When
Saturday
Estimated price
$290 - $1,200
United Airlines
Website
united.com
Flights from Kansas City to Knoxville via Chicago O'Hare
Ave. Duration
4 h 52 min
When
Every day
Estimated price
$250 - $1,200
Flights from Kansas City to Knoxville via Washington Dulles
Ave. Duration
5 h 12 min
When
Every day
Estimated price
$290 - $1,300
Flights from Kansas City to Chattanooga via Chicago O'Hare
Ave. Duration
5 h 22 min
When
Every day
Estimated price
$210 - $1,000
Flights from Kansas City to Asheville via Chicago O'Hare
Ave. Duration
5 h 43 min
When
Every day
Estimated price
$260 - $1,200
Southwest Airlines
Website
southwest.com
Flights from Kansas City to Atlanta
Ave. Duration
1 h 59 min
When
Every day
Estimated price
$220 - $600
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Kansas City Amtrak to St. Louis Gateway Station Amtrak
Ave. Duration
5 h 40 min
Frequency
Twice daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Chattanooga, Tn to Knoxville, Tn
Ave. Duration
1 h 55 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $25
Flexible
$29 - $40
Bus from Atlanta, Ga to Knoxville, Tn
Ave. Duration
4 h 45 min
Frequency
Every 30 minutes
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $45
Flexible
$45 - $65
Bus from Kansas City, Mo to St Louis, Mo
Ave. Duration
4 h
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Bus from St Louis, Mo to Nashville, Tn
Ave. Duration
5 h 40 min
Frequency
Hourly
Estimated price
$35 - $85
Website
greyhound.com
Economy
$35 - $55
Flexible
$65 - $85
Bus from Nashville, Tn to Knoxville, Tn
Ave. Duration
4 h
Frequency
Every 20 minutes
Estimated price
$23 - $55
Website
greyhound.com
Economy
$23 - $35
Flexible
$40 - $55
Bus from Little Rock, Ar to Knoxville, Tn
Ave. Duration
12 h 35 min
Frequency
Every 20 minutes
Estimated price
$50 - $130
Website
greyhound.com
Economy
$50 - $85
Flexible
$100 - $130
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Kansas City, MO to Little Rock, AR
Ave. Duration
8 h 40 min
Frequency
Every 3 hours
Estimated price
$70 - $100
Schedules at
jeffersonlines.com

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