There are 5 ways to get from Kansas City to Knoxville by plane, car, bus or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville  •  6 h 33 min

  1. Fly from Kansas City (MCI) to Knoxville (TYS) MCI - TYS

$276 - $1,172

Cheapest option

Bus, Megabus  •  17 h 9 min

  1. Take the bus from Kansas City, Mo to St Louis, Mo
  2. Take the bus from St Louis, Mo to Nashville, Tn
  3. Take the bus from Nashville, TN to Chattanooga
  4. Take the Megabus from Chattanooga to Knoxville

$90 - $200

3 alternative options

Fly to Asheville, drive  •  8 h 10 min

  1. Fly from Kansas City (MCI) to Asheville (AVL) MCI - AVL
  2. Drive from Asheville to Knoxville

$254 - $1,220

Train, bus, Megabus  •  19 h 16 min

  1. Take the train from Kansas City Amtrak to St. Louis Gateway Station Amtrak
  2. Take the bus from St Louis, Mo to Nashville, Tn
  3. Take the bus from Nashville, TN to Chattanooga
  4. Take the Megabus from Chattanooga to Knoxville

$114 - $261

Drive  •  12 h 7 min

  1. Drive from Kansas City to Knoxville 735.7 miles

$70 - $110

What companies run services between Kansas City, MO, USA and Knoxville, TN, USA?

American Airlines, United Airlines and Delta fly from Kansas City to Knoxville hourly. Alternatively, you can take a bus from Kansas City to Knoxville via St Louis, Mo, Nashville, Tn, Nashville, TN, and Chattanooga in around 17 h 9 min.

Airlines
Delta
Website
delta.com
Flights from Kansas City to Knoxville via Atlanta
Ave. Duration
4 h 58 min
When
Every day
Estimated price
$220 - $1,100
Flights from Kansas City to Knoxville via Detroit
Ave. Duration
4 h 33 min
When
Every day
Estimated price
$240 - $1,200
Flights from Kansas City to Knoxville via Minneapolis
Ave. Duration
5 h 18 min
When
Every day
Estimated price
$250 - $1,200
Flights from Kansas City to Asheville via Atlanta
Ave. Duration
4 h 52 min
When
Every day
Estimated price
$230 - $1,100
American Airlines
Website
aa.com
Flights from Kansas City to Knoxville via Chicago O'Hare
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$240 - $1,100
Flights from Kansas City to Knoxville via Charlotte
Ave. Duration
4 h 47 min
When
Every day
Estimated price
$250 - $1,200
Flights from Kansas City to Knoxville via Dallas/Ft.Worth
Ave. Duration
5 h 30 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,200
Flights from Kansas City to Asheville via Charlotte
Ave. Duration
5 h 23 min
When
Every day
Estimated price
$250 - $1,200
Flights from Kansas City to Asheville via Dallas/Ft.Worth
Ave. Duration
7 h 36 min
When
Saturday
Estimated price
$290 - $1,200
United Airlines
Website
united.com
Flights from Kansas City to Knoxville via Chicago O'Hare
Ave. Duration
4 h 33 min
When
Every day
Estimated price
$250 - $1,200
Flights from Kansas City to Knoxville via Washington Dulles
Ave. Duration
5 h
When
Every day
Estimated price
$290 - $1,300
Flights from Kansas City to Knoxville via Denver
Ave. Duration
5 h 25 min
When
Every day
Estimated price
$320 - $1,400
Flights from Kansas City to Asheville via Chicago O'Hare
Ave. Duration
4 h 49 min
When
Every day
Estimated price
$260 - $1,200
Flights from Kansas City to Asheville via Newark
Ave. Duration
7 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$330 - $1,400
Allegiant Air
Website
allegiantair.com
Flights from Kansas City to Asheville via St. Petersburg
Ave. Duration
5 h 2 min
When
Thursday and Sunday
Estimated price
$240 - $1,200
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Kansas City Amtrak to St. Louis Gateway Station Amtrak
Ave. Duration
5 h 40 min
Frequency
Twice daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Kansas City, Mo to St Louis, Mo
Ave. Duration
4 h
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Bus from St Louis, Mo to Nashville, Tn
Ave. Duration
5 h 40 min
Frequency
Hourly
Estimated price
$35 - $85
Website
greyhound.com
Economy
$35 - $55
Flexible
$65 - $85
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Nashville, TN to Chattanooga
Ave. Duration
2 h 37 min
Frequency
Twice daily
Estimated price
$14 - $25
Schedules at
us.megabus.com
Bus from Chattanooga to Knoxville
Ave. Duration
2 h
Frequency
Twice daily
Estimated price
$12 - $22
Schedules at
us.megabus.com

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Questions & Answers

How far is it from Kansas City to Knoxville?

The distance between Kansas City and Knoxville is 1002 km. The road distance is 1177 km.

What is the cheapest way to get from Kansas City to Knoxville?

The cheapest way to get from Kansas City to Knoxville is to drive which costs $70 - $110 and takes 12 h 7 min.

What is the fastest way to get from Kansas City to Knoxville?

The quickest way to get from Kansas City to Knoxville is to fly which takes 6 h 33 min and costs $270 - $1,200.

Is there a direct bus between Kansas City and Knoxville?

No, there is no direct bus from Kansas City to Knoxville. However, there are services departing from Kansas City, Mo and arriving at Knoxville via St Louis, Mo, Nashville, TN and Chattanooga. The journey, including transfers, takes approximately 17 h 9 min.

How long does it take to get from Kansas City to Knoxville?

It takes approximately 6 h 33 min to get from Kansas City to Knoxville, including transfers.