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There are 6 ways to get from Kansas City to Knoxville by plane, car, bus or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville  •  5 h 57 min

  1. Fly from Kansas City (MCI) to Knoxville (TYS) MCI - TYS

$276 - $1,172

Cheapest option

Bus  •  15 h 40 min

  1. Take the bus from Kansas City, Mo to St Louis, Mo
  2. Take the bus from St Louis, Mo to Nashville, Tn
  3. Take the bus from Nashville, Tn to Knoxville, Tn

$87 - $208

4 alternative options

Fly to Asheville, drive  •  8 h 11 min

  1. Fly from Kansas City (MCI) to Asheville (AVL) MCI - AVL
  2. Drive from Asheville to Knoxville

$244 - $1,120

Train, bus  •  17 h 42 min

  1. Take the train from Kansas City Amtrak to St. Louis Gateway Station
  2. Take the bus from St Louis, Mo to Nashville, Tn
  3. Take the bus from Nashville, Tn to Knoxville, Tn

$111 - $269

Bus via Little Rock, Ar  •  22 h 15 min

  1. Take the bus from Kansas City, MO to Little Rock, AR 121
  2. Take the bus from Little Rock, Ar to Knoxville, Tn 1508 / ...

$123 - $229

Drive  •  12 h 7 min

  1. Drive from Kansas City to Knoxville 735.7 miles

$70 - $110

Questions & Answers

The cheapest way to get from Kansas City to Knoxville is to drive which costs $70 - $110 and takes 12 h 7 min.

More details

The quickest way to get from Kansas City to Knoxville is to fly which costs $270 - $1,200 and takes 5 h 57 min.

More details

No, there is no direct bus from Kansas City to Knoxville. However, there are services departing from Kansas City, Mo and arriving at Knoxville, Tn via St Louis, Mo and Nashville, Tn. The journey, including transfers, takes approximately 15 h 40 min.

More details

The distance between Kansas City and Knoxville is 626 miles. The road distance is 735.7 miles.

Get driving directions

The best way to get from Kansas City to Knoxville without a car is to bus which takes 15 h 40 min and costs $85 - $210.

More details

It takes approximately 5 h 57 min to get from Kansas City to Knoxville, including transfers.

More details

Kansas City to Knoxville bus services, operated by Greyhound USA, depart from Kansas City, Mo station.

More details

The best way to get from Kansas City to Knoxville is to fly which takes 5 h 57 min and costs $270 - $1,200. Alternatively, you can bus, which costs $85 - $210 and takes 15 h 40 min.

Mode details

There is no direct flight from Kansas City Airport to Knoxville Airport. The quickest flight takes 3 h 33 min and has one stopover.

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Kansas City to Knoxville bus services, operated by Greyhound USA, arrive at Knoxville, Tn station.

More details

Map of how to get from Kansas City to Knoxville.
Launch map view
  • Distance: 626.1 miles
  • Duration: 5 h 57 min

What companies run services between Kansas City, MO, USA and Knoxville, TN, USA?

Delta, American Airlines and United Airlines fly from Kansas City to Knoxville hourly. Alternatively, you can take a bus from Kansas City to Knoxville via St Louis, Mo and Nashville, Tn in around 15 h 40 min.

Airlines
Delta
Website
delta.com
Flights from Kansas City to Knoxville via Atlanta
Ave. Duration
4 h 14 min
When
Every day
Estimated price
$220 - $1,100
Flights from Kansas City to Knoxville via Detroit
Ave. Duration
4 h 32 min
When
Every day
Estimated price
$240 - $1,200
Flights from Kansas City to Knoxville via Minneapolis
Ave. Duration
5 h 11 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,200
Flights from Kansas City to Asheville via Atlanta
Ave. Duration
4 h 17 min
When
Every day
Estimated price
$230 - $1,100
American Airlines
Website
aa.com
Flights from Kansas City to Knoxville via Chicago O'Hare
Ave. Duration
4 h 12 min
When
Every day
Estimated price
$240 - $1,100
Flights from Kansas City to Knoxville via Charlotte
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$250 - $1,200
Flights from Kansas City to Knoxville via Dallas/Ft.Worth
Ave. Duration
5 h 4 min
When
Every day
Estimated price
$270 - $1,200
Flights from Kansas City to Asheville via Charlotte
Ave. Duration
4 h 55 min
When
Every day
Estimated price
$250 - $1,200
Flights from Kansas City to Asheville via Chicago O'Hare, Charlotte
Ave. Duration
6 h 55 min
When
Monday, Tuesday and Saturday
Estimated price
$270 - $1,200
Flights from Kansas City to Asheville via Reagan Washington, Charlotte
Ave. Duration
7 h
When
Monday and Tuesday
Estimated price
$290 - $1,200
United Airlines
Website
united.com
Flights from Kansas City to Knoxville via Chicago O'Hare
Ave. Duration
4 h 29 min
When
Every day
Estimated price
$250 - $1,200
Flights from Kansas City to Knoxville via Washington Dulles
Ave. Duration
5 h 18 min
When
Every day
Estimated price
$290 - $1,300
Flights from Kansas City to Asheville via Chicago O'Hare
Ave. Duration
4 h 55 min
When
Every day
Estimated price
$260 - $1,200
Flights from Kansas City to Asheville via Newark
Ave. Duration
8 h 21 min
When
Tuesday, Thursday and Sunday
Estimated price
$330 - $1,400
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Kansas City Amtrak to St. Louis Gateway Station
Ave. Duration
5 h 40 min
Frequency
Twice daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Kansas City, Mo to St Louis, Mo
Ave. Duration
4 h
Frequency
3 times a day
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Bus from St Louis, Mo to Nashville, Tn
Ave. Duration
5 h 40 min
Frequency
4 times a day
Estimated price
$35 - $85
Website
greyhound.com
Economy
$35 - $55
Flexible
$65 - $85
Bus from Nashville, Tn to Knoxville, Tn
Ave. Duration
4 h
Frequency
Every 4 hours
Estimated price
$23 - $55
Website
greyhound.com
Economy
$23 - $35
Flexible
$40 - $55
Bus from Little Rock, Ar to Knoxville, Tn
Ave. Duration
12 h 35 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
greyhound.com
Economy
$50 - $85
Flexible
$100 - $130
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Kansas City, MO to Little Rock, AR
Ave. Duration
8 h 40 min
Frequency
Once daily
Estimated price
$70 - $100
Book at
jeffersonlines.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Knoxville is 1 h ahead of Kansas City. It is currently 1:13 PM in Kansas City and 2:13 PM in Knoxville.

Yes, the driving distance between Kansas City to Knoxville is 736 miles. It takes approximately 12 h 7 min to drive from Kansas City to Knoxville.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Kansas City Airport to Knoxville Airport.

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Book your Kansas City to Knoxville bus tickets online with Greyhound, Greyhound and Greyhound.

Search and book

There are 101+ hotels available in Knoxville. Prices start at $55 USD per night.

More details

The best way to get from Kansas City to Kansas City Airport is to line 229 bus which takes 56 min and costs $2.

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