There are 5 ways to get from Kansas City to Defiance by plane, taxi, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, taxi
best- Fly from Kansas City (MCI) to Fort Wayne International Airport (FWA)plane MCI - FWA
- Take the taxi from Fort Wayne International Airport (FWA) to Defiancetaxi
6h 45m$230–730Drive 647.2 mi
cheapest- Drive from Kansas City to Defiancecar 647.2 mi
11h 1m$111–160Train (Amtrak)
- Take the train from Kansas City to Chicago Union Stationtrain Southwest Chief / ...
- Take the train from Chicago Union Station to Bryan Amtrak Stationtrain Lake Shore Limited
12h 24m$391–599Bus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Union Station to Bryan Amtrak Stationbus
15h 57mTrain, bus (Amtrak)
- Take the train from Kansas City to Chicago Union Stationtrain Southwest Chief / ...
- Take the bus from Chicago Union Station to Bryan Amtrak Stationbus Amtrak Thruway Connecting Service
12h 24m
Kansas City (MCI) to Fort Wayne International Airport (FWA) flights
Comparing Your Travel Options
The cheapest way to get from Kansas City to Defiance is to drive which costs $110 - $160 and takes 11h 1m.
The fastest way to get from Kansas City to Defiance is to fly and taxi which takes 6h 45m and costs $230 - $750.
No, there is no direct bus from Kansas City station to Defiance station. However, there are services departing from Kansas City Bus Station and arriving at Bryan Amtrak Station via St Louis Bus Station and Chicago Union Station. The journey, including transfers, takes approximately 15h 57m.
No, there is no direct train from Kansas City to Defiance station. However, there are services departing from Kansas City and arriving at Bryan Amtrak Station via Chicago Union Station. The journey, including transfers, takes approximately 12h 24m.
The distance between Kansas City and Defiance is 595 miles. The road distance is 651 miles.
The best way to get from Kansas City to Defiance without a car is to train which takes 12h 24m and costs $390 - $600.
It takes approximately 6h 45m to get from Kansas City to Defiance, including transfers.
Kansas City to Defiance bus services, operated by Greyhound USA, depart from Kansas City Bus Station.
Kansas City to Defiance train services, operated by Amtrak, depart from Kansas City station.
The best way to get from Kansas City to Defiance is to train which takes 12h 24m and costs $390 - $600. Alternatively, you can bus, which costs and takes 15h 57m.
What companies run services between Kansas City, MO, USA and Defiance, OH, USA?
You can take a train from Kansas City to Defiance via Chicago Union Station and Bryan Amtrak Station in around 12h 24m. Alternatively, you can take a bus from Kansas City Bus Station to Defiance via St Louis Bus Station, Chicago Bus Station, Chicago Union Station, and Bryan Amtrak Station in around 15h 57m.
- Website
- aa.com
Flights from Kansas City to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $90–550
Flights from Kansas City to Fort Wayne International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $150–700
Flights from Kansas City to Fort Wayne International Airport via Charlotte
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $140–700
- Website
- delta.com
Flights from Kansas City to Fort Wayne International Airport via Minneapolis
- Ave. Duration
- 4h 9m
- When
- Wednesday, Friday, Sunday, and Saturday
- Estimated price
- $110–600
Flights from Kansas City to Fort Wayne International Airport via Atlanta
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $140–700
Flights from Kansas City to Fort Wayne International Airport via Detroit
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $100–600
- Website
- united.com
Flights from Kansas City to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kansas City to Chicago Union Station
- Ave. Duration
- 7h 41m
- Frequency
- Twice daily
- Estimated price
- $240–370
- Website
- Amtrak
Train from Chicago Union Station to Bryan Amtrak Station
- Ave. Duration
- 3h 13m
- Frequency
- Twice daily
- Estimated price
- $95–160
- Website
- Amtrak
Train from Kansas City to Chicago Union Station
- Ave. Duration
- 7h 41m
- Frequency
- Twice daily
- Estimated price
- $240–370
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- Every 4 hours
- Estimated price
- $45–70
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- 4 times a day
- Estimated price
- $50–80
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Bryan Amtrak Station
- Ave. Duration
- 3h 13m
- Frequency
- Once a week
- Website
- Amtrak
Bus from Chicago Union Station to Bryan Amtrak Station
- Ave. Duration
- 3h 13m
- Frequency
- Once a week
- Website
- Amtrak
- Ave. Duration
- 1h 5m
- Estimated price
- $140–180
Deluxe Taxi Co
- Phone
- +1-260-426-8555
- Website
- deluxetaxifortwayne.net
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Kansas City to Defiance bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Defiance is 1h ahead of Kansas City. It is currently 7:14 PM in Kansas City and 8:14 PM in Defiance.
Kansas City to Defiance train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Kansas City to Defiance is 651 miles. It takes approximately 11h 1m to drive from Kansas City to Defiance.
There are 14+ hotels available in Defiance.









