From Kalabaka bus to Preveza then bus to Lefkáda. 6 h 6 min 30€. From Kalampáka bus to Trikala, bus to Preveza, then bus to Lefkáda. 7 h 15 min 3€. From Kalampáka drive to Lefkada. 3 h 4 min 33€.
No, there is no direct bus from Kalampáka to Lefkada. However, there are services departing from Kalabaka and arriving at Lefkáda via Preveza. The journey, including transfers, takes approximately 6 h 6 min.