There are 7 ways to get from Jacksonville to Iowa by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Des Moines
best- Fly from Jacksonville (JAX) to Des Moines (DSM)plane JAX - DSM
4h 43m$239–1,224Fly to Quad City International Airport
cheapest- Fly from Jacksonville (JAX) to Quad City International Airport (MLI)plane JAX - MLI
7h 37m$104–555Bus
- Take the bus from Jacksonville to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Des Moinesbus
29h 44m$168–451Train, bus
- Take the train from Jacksonville to Chicago Union Stationtrain Floridian
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123 / ...
44h 28m$270–1,224Drive 1,191.5 mi
- Drive from Jacksonville to Des Moinescar 1,191.5 mi
21h 48m$218–315Fly to Omaha
- Fly from Jacksonville (JAX) to Omaha (OMA)plane JAX - OMA
6h 50m$227–1,133Fly to Waterloo Municipal Airport
- Fly from Jacksonville (JAX) to Waterloo Municipal Airport (ALO)plane JAX - ALO
7h 14m$139–624
Jacksonville (JAX) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Jacksonville to Iowa is to drive which costs $210 - $320 and takes 21h 48m.
The fastest way to get from Jacksonville to Iowa is to fly which takes 4h 43m and costs $230 - $1,300.
The distance between Jacksonville and Iowa is 1041 miles. The road distance is 1198.4 miles.
The best way to get from Jacksonville to Iowa without a car is to bus which takes 29h 44m and costs $160 - $460.
It takes approximately 4h 43m to get from Jacksonville to Iowa, including transfers.
The best way to get from Jacksonville to Iowa is to fly which takes 4h 43m and costs $230 - $1,300. Alternatively, you can bus, which costs $160 - $460 and takes 29h 44m.
Iowa is 1h behind Jacksonville. It is currently 4:42 AM in Jacksonville and 3:42 AM in Iowa.
Yes, the driving distance between Jacksonville to Iowa is 1198 miles. It takes approximately 21h 48m to drive from Jacksonville to Iowa.
There are 200+ hotels available in Iowa.
What companies run services between Jacksonville, FL, USA and Iowa, USA?
Allegiant Air, American Airlines, and Delta fly from Jacksonville (JAX) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Jacksonville to Des Moines via Atlanta Bus Station, Chicago Bus Station, and Des Moines in around 29h 44m.
- Website
- aa.com
Flights from Jacksonville to Des Moines via Charlotte
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $240–1,200
Flights from Jacksonville to Omaha via Charlotte
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $220–1,100
Flights from Jacksonville to Omaha via Chicago O'Hare
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Jacksonville to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $110–600
Flights from Jacksonville to Quad City International Airport via Charlotte
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $110–600
Flights from Jacksonville to Quad City International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $160–750
Flights from Jacksonville to Waterloo Municipal Airport via Chicago O'Hare
- Ave. Duration
- 7h 58m
- When
- Every day
- Estimated price
- $120–600
- Website
- delta.com
Flights from Jacksonville to Des Moines via Atlanta
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Jacksonville to Des Moines via Detroit
- Ave. Duration
- 6h
- When
- Monday, Thursday, and Friday
- Estimated price
- $270–1,300
Flights from Jacksonville to Omaha via Atlanta
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Jacksonville to Omaha via Minneapolis
- Ave. Duration
- 6h 18m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $250–1,200
Flights from Jacksonville to Quad City International Airport via Atlanta
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $100–550
- Website
- united.com
Flights from Jacksonville to Omaha via Chicago O'Hare
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $230–1,100
Flights from Jacksonville to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 7h 11m
- When
- Every day
- Estimated price
- $110–600
- Website
- southwest.com
Flights from Jacksonville to Omaha via Nashville
- Ave. Duration
- 4h 40m
- When
- Monday
- Estimated price
- $200–1,100
Flights from Jacksonville to Omaha via St. Louis
- Ave. Duration
- 8h 30m
- When
- Saturday
- Estimated price
- $200–1,100
- Website
- allegiantair.com
Flights from Jacksonville to Des Moines
- Ave. Duration
- 2h 37m
- When
- Thursday
- Estimated price
- $220–1,200
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Chicago Union Station
- Ave. Duration
- 35h 16m
- Frequency
- Once daily
- Estimated price
- $220–1,100
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- 3 times a day
- Estimated price
- $45–110
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 14h 25m
- Frequency
- 3 times a day
- Estimated price
- $80–190
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 8h 45m
- Frequency
- Once daily
- Estimated price
- $45–120
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 16h
- Frequency
- 4 times a day
- Estimated price
- $75–210
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $40–110
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide






