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How to get fromIthaca to Natickby bus (Flixbus, Greyhound), bus, train, car, or plane

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There are 9 ways to get from Ithaca to Natick by bus (Flixbus, Greyhound), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Ithaca to Springfield Union Stationbus bus FlixBus 2691
    2. Take the bus from Springfield Union Station to Framinghambus bus Greyhound US0270s
    10h 13m
    $51–86

  2. Bus, train

    1. Take the bus from Ithaca to Utica Bus Stopbus bus FlixBus 2691
    2. Take the train from Utica Amtrak Station to Framingham Amtraktrain train Lake Shore Limited
    11h 31m
    $87–202

  3. Drive 315.1 mi

    1. Drive from Ithaca to Natickcar car 315.1 mi
    5h 55m
    $58–84

  4. Fly from Ithaca Tompkins Regional Airport

    1. Fly from Ithaca Tompkins Regional Airport (ITH) to Boston Logan Airport (BOS)plane plane ITH - BOS
    7h 30m
    $65–343

  5. Bus, train via New York

    1. Take the bus from Ithaca to New Yorkbus bus
    2. Take the bus from New York to Worcesterbus bus
    3. Take the train from Worcester to Natick Centertrain train
    11h 42m
    $86–253

  6. Bus to Rochester, fly

    1. Take the bus from Ithaca to Rochester, Nybus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    6h 15m
    $112–495

  7. Bus to Syracuse Hancock International Airport, fly

    1. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    2. Fly from Syracuse Hancock International Airport (SYR) to Boston Logan Airport (BOS)plane plane SYR - BOS
    6h 32m
    $84–489

  8. Bus to Buffalo Niagara International Airport, fly

    1. Take the bus from Ithaca to Buffalobus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    7h 50m
    $89–423

  9. Bus to Newark Liberty International Airport, fly

    1. Take the bus from Ithaca to Newark Penn Stationbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Boston Logan Airport (BOS)plane plane EWR - BOS
    8h 52m
    $541–1,391

Ithaca to Natick by bus

Calendar3Weekly Buses
Duration10h 13mAverage Duration
Ticket$51Cheapest Price
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Questions & Answers

Map of how to get from Ithaca to Natick.ExpandLaunch map view
  • Distance: 362.8 mi
  • Duration: 10h 13m

What companies run services between Ithaca, NY, USA and Natick, MA, USA?

You can take a bus from Ithaca to Natick Center MBTA via Springfield Union Station, Framingham, and Framingham MBTA Station in around 10h 13m. Alternatively, United Airlines and Delta fly from Ithaca Tompkins Regional Airport (ITH) to Boston Logan Airport (BOS) every 4 hours.

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