There are 8 ways to get from Ithaca to Key West by plane, bus, shuttle, train, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Ithaca Tompkins Regional Airport
best- Fly from Ithaca Tompkins Regional Airport (ITH) to Key West International Airport (EYW)ITH - EYW
13h 3m$123–524Bus, shuttle
- Take the bus from Ithaca to Washington Union Station
- Take the bus from Washington Union Station to Orlando Bus Station
- Take the bus from Orlando Bus Station to Downtown Miami
- Take a shuttle bus from Bayside Marketplace to Plaza Hotel
39h 31m$264–469Bus, train
- Take the bus from Ithaca to Newark Penn Station
- Take the train from Newark Penn Station to Miami Amtrak Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
39h 51m$303–1,159Drive 1,505.1 mi
- Drive from Ithaca to Key West1,505.1 mi
26h 55m$275–397Bus to Syracuse Hancock International Airport, fly
- Take the bus from Ithaca, NY to Syracuse Airport, NY
- Fly from Syracuse Hancock International Airport (SYR) to Key West International Airport (EYW)SYR - EYW
8h 33m$231–1,015Bus to Rochester, fly
- Take the bus from Ithaca, NY to Rochester, NY
- Fly from Rochester (ROC) to Key West International Airport (EYW)ROC - EYW
9h 8m$171–769Bus to Newark Liberty International Airport, fly
- Take the bus from Ithaca to Newark Penn Station
- Fly from Newark Liberty International Airport (EWR) to Key West International Airport (EYW)EWR - EYW
8h 34m$171–554Bus
- Take the bus from Ithaca to Newark Penn Station
- Take the bus from Newark Penn Station to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
47h 26m$239–550
Ithaca to Key West by bus, train, taxi, and foot
Questions & Answers
The cheapest way to get from Ithaca to Key West is to bus and fly which costs $170 - $600 and takes 8h 34m.
The fastest way to get from Ithaca to Key West is to bus and fly which takes 8h 33m and costs $230 - $1,100.
No, there is no direct bus from Ithaca to Key West. However, there are services departing from Ithaca and arriving at N Roosevelt & 3rd Street via Newark Penn Station, Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 47h 26m.
The distance between Ithaca and Key West is 1293 miles. The road distance is 1513.9 miles.
The best way to get from Ithaca to Key West without a car is to bus and shuttle which takes 39h 31m and costs $260 - $470.
It takes approximately 13h 3m to get from Ithaca to Key West, including transfers.
Ithaca to Key West bus services, operated by Flixbus USA, depart from Ithaca station.
The best way to get from Ithaca to Key West is to fly which takes 13h 3m and costs $120 - $550. Alternatively, you can bus, which costs $230 - $550 and takes 47h 26m.
Ithaca to Key West bus services, operated by Flixbus USA, arrive at Newark Penn Station.
Yes, the driving distance between Ithaca to Key West is 1514 miles. It takes approximately 26h 55m to drive from Ithaca to Key West.
What companies run services between Ithaca, NY, USA and Key West, FL, USA?
United Airlines, Delta, and two other airlines fly from Ithaca Tompkins Regional Airport (ITH) to Key West International Airport (EYW) 4 times a day. Alternatively, you can take a bus from Ithaca to N Roosevelt & 3rd Street via Newark Penn Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 47h 26m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Ithaca Tompkins Regional Airport to Key West International Airport via New York JFK, Miami
- Ave. Duration
- 13h 12m
- When
- Every day
- Estimated price
- $120–550
Flights from Syracuse Hancock International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 12m
- When
- Monday, Tuesday, Wednesday, Friday, and Saturday
- Estimated price
- $200–950
Flights from Rochester to Key West International Airport via Charlotte
- Ave. Duration
- 7h 25m
- When
- Every day
- Estimated price
- $140–700
Flights from Rochester to Key West International Airport via Miami
- Ave. Duration
- 6h 26m
- When
- Saturday
- Estimated price
- $140–700
Flights from Rochester to Key West International Airport via Reagan Washington
- Ave. Duration
- 10h 9m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–700
Flights from Newark Liberty International Airport to Key West International Airport via Miami
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $90–440
- Website
- delta.com
Flights from Syracuse Hancock International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $210–950
Flights from Rochester to Key West International Airport via Atlanta
- Ave. Duration
- 6h 41m
- When
- Every day
- Estimated price
- $150–700
- Website
- united.com
Flights from Ithaca Tompkins Regional Airport to Key West International Airport via Washington Dulles
- Ave. Duration
- 15h 44m
- When
- Every day
- Estimated price
- $110–550
Flights from Newark Liberty International Airport to Key West International Airport
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- $90–440
- Website
- flybreeze.com
Flights from Ithaca Tompkins Regional Airport to Key West International Airport via Washington Dulles, Raleigh/Durham
- Ave. Duration
- 14h 34m
- When
- Thursday and Sunday
- Estimated price
- $210–800
- Website
- allegiantair.com
Flights from Syracuse Hancock International Airport to Key West International Airport via St. Petersburg
- Ave. Duration
- 8h 26m
- When
- Sunday
- Estimated price
- $200–950
- Website
- spirit.com
Flights from Newark Liberty International Airport to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 5h 34m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $95–390
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Newark Penn Station to Miami Amtrak Station
- Ave. Duration
- 28h 6m
- Frequency
- Once daily
- Estimated price
- $210–1,000
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Ithaca to Washington Union Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $75–140
- Schedules at
- flixbus.com
Bus from Washington Union Station to Orlando Bus Station
- Ave. Duration
- 16h 25m
- Frequency
- 5 times a week
- Estimated price
- $95–220
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Downtown Miami
- Ave. Duration
- 5h
- Frequency
- 4 times a day
- Estimated price
- $28–50
- Schedules at
- flixbus.com
Bus from Ithaca to Newark Penn Station
- Ave. Duration
- 3h 45m
- Frequency
- 4 times a week
- Estimated price
- $45–90
- Schedules at
- flixbus.com
Bus from Newark Penn Station to Atlanta Bus Station
- Ave. Duration
- 18h 5m
- Frequency
- 5 times a week
- Estimated price
- $100–220
- Schedules at
- flixbus.com
- Phone
- (+1) 305-600-2226
- lyberi.com@gmail.com
- Website
- lyberi.com
Shuttle from Bayside Marketplace to Plaza Hotel
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $60
- Website
- https://lyberi.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Newark Penn Station to Atlanta Bus Station
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- $100–200
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 14h 5m
- Frequency
- Once daily
- Estimated price
- $70–200
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 600-1455
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Ithaca, NY to Syracuse Airport, NY
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a week
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
Bus from Ithaca, NY to Rochester, NY
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $20–60
- Website
- https://www.ourbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 868+ hotels available in Key West.









