There are 10 ways to get from Ithaca to Indiana by bus, plane, train, bus (Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Elmira/Corning Regional Airport, fly to South Bend
best- Take the bus from Ithaca - Tioga Street and Seneca Street to Transit Center - PO Sidebus
- Fly from Elmira/Corning Regional Airport (ELM) to South Bend (SBN)plane ELM - SBN
8h 21mBus
cheapest- Take the bus from Ithaca to Buffalobus
- Take the bus from Buffalo, NY to Columbus - Mound Stbus
- Take the bus from Columbus to Indianapolisbus
16h 39m$77–151Bus, train via Toledo
- Take the bus from Ithaca to Rochester, Nybus 246
- Take the train from Rochester to Toledotrain
- Take the bus from Toledo to Indianapolis, INbus
14h 39m$122–299Drive 622.3 mi
- Drive from Ithaca to Indianapoliscar 622.3 mi
11h 17m$114–165Bus to Rochester, fly to Chicago Midway International Airport, train
- Take the bus from Ithaca to Rochester, Nybus
- Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane ROC - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
6h 52m$149–741Bus to Rochester, fly to Chicago O'Hare International Airport, train
- Take the bus from Ithaca to Rochester, Nybus
- Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)plane ROC - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
7h 14m$249–551Bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport, train
- Take the bus from Ithaca to Buffalobus
- Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane BUF - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
8h 12m$148–845Bus to Syracuse Hancock International Airport, fly to Chicago O'Hare International Airport, train
- Take the bus from Ithaca to Syracuse Bus Stationbus
- Fly from Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD)plane SYR - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
7h 57m$84–433Bus, train
- Take the bus from Ithaca to Syracuse Bus Stationbus
- Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
21h 16m$197–452Bus via New York
- Take the bus from Ithaca, NY to New York, NYbus
- Take the bus from Willow Ave At 15Th St to Port Authority Bus Terminalbus 126 / ...
- Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus
22h 35m$156–335
Ithaca to Indiana by bus and train
Questions & Answers
The cheapest way to get from Ithaca to Indiana is to bus which costs $75 - $160 and takes 16h 39m.
The fastest way to get from Ithaca to Indiana is to bus and fly and train which takes 6h 52m and costs $140 - $750.
No, there is no direct bus from Ithaca to Indiana. However, there are services departing from Ithaca and arriving at Indianapolis via Buffalo, NY, S Grant Ave & E Mound St and Columbus. The journey, including transfers, takes approximately 16h 39m.
The distance between Ithaca and Indiana is 538 miles. The road distance is 626 miles.
The best way to get from Ithaca to Indiana without a car is to bus and train via Toledo which takes 14h 39m and costs $120 - $300.
It takes approximately 8h 21m to get from Ithaca to Indiana, including transfers.
Ithaca to Indiana bus services, operated by Trailways, depart from Ithaca station.
Ithaca to Indiana bus services, operated by Trailways, arrive at Buffalo station.
Yes, the driving distance between Ithaca to Indiana is 626 miles. It takes approximately 11h 17m to drive from Ithaca to Indiana.
Book your Ithaca to Indiana bus tickets online with Omio.
What companies run services between Ithaca, NY, USA and Indiana, USA?
You can take a bus from Ithaca to Indianapolis via Buffalo, NY, Columbus - Mound St, S Grant Ave & E Mound St, S High St & E Rich St, and Columbus in around 16h 39m.
- Website
- delta.com
Flights from Elmira/Corning Regional Airport to South Bend via Detroit
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $75–470
Flights from Rochester to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–650
Flights from Rochester to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $60–380
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–800
Flights from Syracuse Hancock International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $65–380
- Website
- aa.com
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 2h 14m
- When
- Every day
- Estimated price
- $60–380
Flights from Rochester to Chicago O'Hare International Airport via Philadelphia
- Ave. Duration
- 4h 58m
- When
- Tuesday and Wednesday
- Estimated price
- $85–460
Flights from Syracuse Hancock International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 24m
- When
- Every day
- Estimated price
- $65–380
Flights from Syracuse Hancock International Airport to Chicago O'Hare International Airport via Reagan Washington
- Ave. Duration
- 4h 49m
- When
- Sunday
- Estimated price
- $85–440
- Website
- united.com
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $60–380
Flights from Rochester to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $85–450
Flights from Syracuse Hancock International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 29m
- When
- Every day
- Estimated price
- $65–380
Flights from Syracuse Hancock International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $80–440
- Website
- southwest.com
Flights from Rochester to Chicago Midway International Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $100–650
Flights from Rochester to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 4h 30m
- When
- Monday to Saturday
- Estimated price
- $140–800
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $120–800
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Rochester to Toledo
- Ave. Duration
- 6h 44m
- Frequency
- Twice daily
- Estimated price
- $80–180
- Website
- https://www.amtrak.com/home.html
Train from Syracuse Regional Transportation Center to Chicago Union Station
- Ave. Duration
- 13h 7m
- Frequency
- Twice daily
- Estimated price
- $150–340
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $40–100
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- $7–9
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–9
- Phone
- +1 607-734-5211
- Website
- ridectran.com
Bus from Ithaca - Tioga Street and Seneca Street to Transit Center - PO Side
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Website
- https://ridectran.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Ithaca to Rochester, Ny
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- $20–55
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $20–55
- Flexible
- $40–55
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 50m
- Frequency
- Twice daily
- Estimated price
- $29–100
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $29–95
- Flexible
- $55–100
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Toledo to Indianapolis, IN
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- https://baronsbus.com
Bus from Buffalo, NY to Columbus - Mound St
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- https://baronsbus.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $19–35
- Schedules at
- flixbus.com
Bus from Columbus to Indianapolis
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $20–35
- Schedules at
- flixbus.com
Bus from Ithaca to Syracuse Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a week
- Estimated price
- $7–13
- Schedules at
- flixbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Ithaca, NY to New York, NY
- Ave. Duration
- 4h 20m
- Frequency
- 5 times a day
- Estimated price
- $20–75
- Website
- https://www.ourbus.com
- Phone
- +1 973-275-5555
- Website
- njtransit.com
Bus from Willow Ave At 15Th St to Port Authority Bus Terminal
- Ave. Duration
- 9 min
- Frequency
- Every 5 minutes
- Estimated price
- $6–21
- Website
- https://www.njtransit.com
- Schedules at
- https://www.njtransit.com/bus-to
- Adults
- $6–21
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Port Authority Bus Terminal to Indianapolis Union Station
- Ave. Duration
- 17h 5m
- Frequency
- 3 times a day
- Estimated price
- $130–240
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 878+ hotels available in Indiana.

















