There are 4 ways to get from Italy to Mendrisio by train, bus, car, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Roma Termini to Milano Centraletrain 9950 / ...
- Take the train from Milano Centrale to Mendrisiotrain Re80
4h 39mCHF 88–193Train via Rome Termini
cheapest- Take the train from Roma Termini to Milano Centraletrain Fr / ...
- Take the train from Milano Centrale to Mendrisiotrain Re80
5h 14mCHF 87–212Bus
- Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus 510 / ...
- Take the bus from Florence Villa Constanza Bus Station to Comobus
9h 7mDrive 627.9 km
- Drive from Rome to Mendrisiocar 627.9 km
6h 2mCHF 103–148
Italy to Mendrisio by train
Questions & Answers
The cheapest way to get from Italy to Mendrisio is to train which costs SFr 85 - SFr 200 and takes 4h 39m.
The fastest way to get from Italy to Mendrisio is to train which takes 4h 39m and costs SFr 85 - SFr 200.
No, there is no direct bus from Italy to Mendrisio. However, there are services departing from Termini and arriving at Mendrisio, Autosilo via Roma, Autostazione Tiburtina, Florence Villa Constanza Bus Station, Como - Chiesa di San Zenone and Chiasso, Stazione. The journey, including transfers, takes approximately 9h 7m.
No, there is no direct train from Italy to Mendrisio. However, there are services departing from Roma Termini and arriving at Mendrisio via Milano Centrale. The journey, including transfers, takes approximately 4h 39m.
The distance between Italy and Mendrisio is 639 km. The road distance is 627.9 km.
The best way to get from Italy to Mendrisio without a car is to train which takes 4h 39m and costs SFr 85 - SFr 200.
It takes approximately 4h 39m to get from Italy to Mendrisio, including transfers.
Italy to Mendrisio bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Italy to Mendrisio train services, operated by ItaloTreno, depart from Roma Termini station.
The best way to get from Italy to Mendrisio is to train which takes 4h 39m and costs SFr 85 - SFr 200. Alternatively, you can bus, which costs and takes 9h 7m.
What companies run services between Italy and Mendrisio, Switzerland?
You can take a train from Roma Termini to Mendrisio via Milano Centrale in around 4h 39m. Alternatively, you can take a bus from Termini to Mendrisio, Autosilo via Roma, Autostazione Tiburtina, Florence Villa Constanza Bus Station, Como, Como - Chiesa di San Zenone, and Chiasso, Stazione in around 9h 7m.
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- CHF 65–140
- Website
- https://www.italotreno.it/en
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 15m
- Frequency
- Every 2 hours
- Estimated price
- CHF 65–130
- Website
- https://www.italotreno.it/en
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 20–60
- Website
- https://www.sbb.ch/en
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 20–60
- Website
- https://www.sbb.ch/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 40m
- Frequency
- Every 30 minutes
- Estimated price
- CHF 75–160
- Schedules at
- trenitalia.com
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- CHF 21–35
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- CHF 16–30
- Website
- https://www.itabus.it/en/home
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- CHF 22–40
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 0972 24590
- booking@autolineemoretti.it
- Website
- autolineemoretti.it
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- 3 times a week
- Estimated price
- CHF 18–20
- Schedules at
- autolineemoretti.it
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- onebus.it
Bus from Florence Villa Constanza Bus Station to Como
- Ave. Duration
- 3h 7m
- Frequency
- Once a week
- Website
- https://onebus.it/
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More Questions & Answers
Italy to Mendrisio bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Italy to Mendrisio train services, operated by ItaloTreno, arrive at Milano Centrale station.
Yes, the driving distance between Italy to Mendrisio is 628 km. It takes approximately 6h 2m to drive from Italy to Mendrisio.
There are 5856+ hotels available in Mendrisio.

























