There are 10 ways to get from Istanbul to Niš by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus Metro Plus  •  13 h

  1. Take the bus from Istanbul to Sofia
  2. Take the bus from Sofia to Niš

$40 - $78

Cheapest option

Bus MetroTurizm  •  14 h 12 min

  1. Take the bus from Istanbul Otogari to Sofia
  2. Take the bus from Sofia to Niš

$23 - $51

8 alternative options

Train, bus  •  17 h 17 min

  1. Take the train from Halkalı Station to Kapıkule Station
  2. Take the train from Svilengrad to Sofia
  3. Take the bus from Sofia to Niš

$30 - $40

Drive  •  7 h 26 min

  1. Drive from Istanbul to Niš 444.9 miles

$90 - $140

Fly Istanbul to Pristina, drive, line 7830 train, bus  •  9 h 1 min

  1. Fly from Istanbul (IST) to Pristina (PRN) IST - PRN
  2. Drive from Pristina to Vasiljevac Stajaliste
  3. Take the line 7830 train from Vasiljevac Stajaliste to Pepeljevac
  4. Take the bus from Pepeljevac to Niš

Fly Istanbul to Sofia, bus  •  9 h 40 min

  1. Fly from Istanbul (IST) to Sofia (SOF) IST - SOF
  2. Take the bus from Sofia to Niš

$78 - $219

Fly Istanbul to Belgrade, bus  •  9 h 36 min

  1. Fly from Istanbul (IST) to Belgrade (BEG) IST - BEG
  2. Take the bus from Belgrade to Niš

$71 - $258

Fly Istanbul to Skopje, bus  •  10 h 3 min

  1. Fly from Istanbul (IST) to Skopje (SKP) IST - SKP
  2. Take the bus from Skopje to Niš

$85 - $181

Fly Sabiha Gokcen to Pristina, drive, line 7830 train, bus  •  10 h 26 min

  1. Fly from Sabiha Gokcen (SAW) to Pristina (PRN) SAW - PRN
  2. Drive from Pristina to Vasiljevac Stajaliste
  3. Take the line 7830 train from Vasiljevac Stajaliste to Pepeljevac
  4. Take the bus from Pepeljevac to Niš

Fly Sabiha Gokcen to Skopje, bus  •  11 h 22 min

  1. Fly from Sabiha Gokcen (SAW) to Skopje (SKP) SAW - SKP
  2. Take the bus from Skopje to Niš

$73 - $1,327

Questions & Answers

The cheapest way to get from Istanbul to Niš is to bus which costs 110 ₺ - 250 ₺ and takes 14 h 12 min.

More details

The quickest way to get from Istanbul to Niš is to drive which costs 440 ₺ - 650 ₺ and takes 7 h 26 min.

More details

The distance between Istanbul and Niš is 635 km. The road distance is 711.8 km.

Get driving directions

It takes approximately 13 h to get from Istanbul to Niš, including transfers.

More details

No, there is no direct bus from Istanbul to Niš. However, there are services departing from Istanbul and arriving at Niš via Sofia. The journey, including transfers, takes approximately 13 h.

More details

What companies run services between Istanbul, Turkey and Niš, Serbia?

You can take a bus from Istanbul to Niš via Sofia in around 13 h.

Airlines
Turkish Airlines
Website
p.turkishairlines.com
Flights from Istanbul to Pristina
Ave. Duration
1 h 37 min
When
Every day
Estimated price
$90 - $250
Flights from Istanbul to Sofia
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$120 - $290
Flights from Istanbul to Belgrade
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$110 - $600
Flights from Istanbul to Skopje
Ave. Duration
1 h 32 min
When
Every day
Estimated price
$110 - $320
Pegasus Airlines
Website
flypgs.com
Flights from Sabiha Gokcen to Pristina
Ave. Duration
1 h 42 min
When
Every day
Estimated price
$50 - $250
Flights from Sabiha Gokcen to Skopje
Ave. Duration
1 h 33 min
When
Monday, Tuesday, Thursday, Friday, Saturday and Sunday
Estimated price
$50 - $350
AtlasGlobal
Website
atlasglb.com
Flights from Istanbul to Belgrade
Ave. Duration
1 h 50 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$60 - $320
Train operators
Turkish Railways (TCDD)
Phone
+90 444 8 233
Website
tcddtasimacilik.gov.tr
Train from Halkalı Station to Kapıkule Station
Ave. Duration
4 h 27 min
Frequency
Once daily
Estimated price
$4 - $5
Website
tcdd.gov.tr
Bulgarian Railways (BDZh)
Serbian Railways
Website
srbvoz.rs
Train from Vasiljevac Stajaliste to Pepeljevac
Ave. Duration
1 h 7 min
Frequency
Twice daily
Estimated price
$1 - $3
Schedules at
srbvoz.rs
2nd Class Ticket
$1 - $2
1st Class Ticket
$1 - $3
Bus operators
Metro Plus
Website
metrotransport.bg
Bus from Istanbul to Sofia
Ave. Duration
9 h
Frequency
4 times a day
Estimated price
$30 - $65
Schedules at
metrotransport.bg
Matpu
Phone
02 952 50 04
Email
matpu96@abv.bg
Website
matpu.com
Bus from Sofia to Niš
Ave. Duration
3 h
Frequency
Twice daily
Estimated price
$10 - $15
Schedules at
matpu.com
Nis Ekspres
Phone
+381 18 255 177
Email
marketing@nis-ekspres.rs
Website
nis-ekspres.rs
Bus from Sofia to Niš
Ave. Duration
4 h
Frequency
Twice daily
Estimated price
$7 - $13
Schedules at
nis-ekspres.rs
Book at
onlinetickets.nis-ekspres.rs
Bus from Belgrade to Niš
Ave. Duration
3 h 10 min
Frequency
4 times a day
Estimated price
$11
Schedules at
nis-ekspres.rs
Book at
onlinetickets.nis-ekspres.rs
Bus from Skopje to Niš
Ave. Duration
3 h 34 min
Frequency
Once daily
Estimated price
$10
Schedules at
nis-ekspres.rs
Book at
onlinetickets.nis-ekspres.rs
MetroTurizm
Website
metroturizm.com.tr
Bus from Istanbul Otogari to Sofia
Ave. Duration
9 h
Frequency
4 times a day
Estimated price
$12 - $19
Schedules at
metroturizm.com.tr
Alpar Turizm
Phone
0090 212 658 18 51
Email
info@alparturizm.com.tr
Website
alparturizm.com.tr
Bus from Istanbul to Sofia
Ave. Duration
9 h 15 min
Frequency
Once daily
Estimated price
$18 - $35
Schedules at
alparturizm.com.tr
Huntur Travel
Website
huntur.com.tr
Bus from Istanbul to Sofia
Ave. Duration
9 h 45 min
Frequency
Once daily
Estimated price
$12 - $17
Schedules at
huntur.com.tr
Lasta
Website
lasta.rs
Bus from Pepeljevac to Niš
Ave. Duration
57 min
Frequency
3 times a day
Estimated price
$2 - $3
Schedules at
lasta.rs
Bus from Belgrade to Niš
Ave. Duration
3 h 25 min
Frequency
Once daily
Estimated price
$10 - $12
Schedules at
lasta.rs
BS Tours
Phone
011 761-4693
Email
bstours@verat.net
Website
bstours.rs
Bus from Belgrade to Niš
Ave. Duration
3 h 5 min
Frequency
Twice daily
Estimated price
$11 - $30
Schedules at
bstours.rs
AD Galeb Ohrid
Phone
(389) 46 251-882
Email
info@galeb.mk
Website
adgaleb.com.mk
Bus from Skopje to Niš
Ave. Duration
3 h 29 min
Frequency
Once daily
Estimated price
$14 - $20
Schedules at
adgaleb.com.mk
Autoprevoz Cacak
Phone
+381 32 322 461
Email
info@kavim-serbia.rs
Website
autoprevoz-cacak.rs
Bus from Skopje to Niš
Ave. Duration
4 h 2 min
Frequency
Once daily
Estimated price
$10
Schedules at
autoprevoz-cacak.rs

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Need to know: Jadrolinija, How do I buy a London Underground ticket? and Want to know more about US trains? - to help you get the most out of your next trip.