There are 6 ways to get from Ispra to Lyon by train (Trenitalia), train, bus, car, plane, train (TGV, Trenitalia), or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Turin
best- Take the train from Varese to Rho Fiera Milanotrain S5 / ...
- Take the train from Rho-Fiera Milano to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Lyon Part Dieutrain Fr
7h 36m€58–109Train, bus
cheapest- Take the train from Varese to Rho Fiera Milanotrain S5 / ...
- Take the bus from Milan Lampugnano to Lyon Lyon Perrache Bus Stationbus Itabus
9h 41m€32–71Drive 431.5 km
- Drive from Ispra to Lyoncar 431.5 km
4h 37m€70–101Bus, train, fly
- Take the bus from Ispra, Mazzini/Roma,distributore to Varese, Morosini,Stazione FS FNbus
- Take the train from Varese to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Lyon–Saint Exupéry Airport (LYS)plane MXP - LYS
5h 30m€84–231Train
- Take the train from Varese to Milano Porta Garibalditrain S5 / ...
- Take the train from Milano P.Garibaldi to Chambery Challes Les Eauxtrain Tgv
- Take the train from Chambery Challes Les Eaux to Lyon Part Dieutrain Ter
9h 5m€86–169Ferry, bus
- Take the ferry from Angera to Aronaferry 507
- Take the bus from Milan to Turinbus 467 / ...
- Take the bus from Turin to Lyonbus 480 / ...
10h 2m€47–79
Ispra to Lyon by bus and train
Comparing Your Travel Options
The cheapest way to get from Ispra to Lyon is to train and bus which costs €30 - €75 and takes 9h 41m.
The fastest way to get from Ispra to Lyon is to drive which takes 4h 37m and costs €65 - €110.
No, there is no direct train from Ispra to Lyon. However, there are services departing from Varese and arriving at Lyon Part Dieu via Rho-Fiera Milano and Torino Porta Susa. The journey, including transfers, takes approximately 7h 36m.
The distance between Ispra and Lyon is 509 km. The road distance is 431.5 km.
The best way to get from Ispra to Lyon without a car is to train via Turin which takes 7h 36m and costs €55 - €110.
It takes approximately 7h 36m to get from Ispra to Lyon, including transfers.
Ispra to Lyon train services, operated by Trenord, depart from Varese station.
Ispra to Lyon train services, operated by Trenord, arrive at Rho Fiera Milano station.
Yes, the driving distance between Ispra to Lyon is 431 km. It takes approximately 4h 37m to drive from Ispra to Lyon.
There are 1422+ hotels available in Lyon.
What companies run services between Ispra, Italy and Lyon, France?
You can take a bus from Ispra, Mazzini/Roma,distributore to Lyon Part Dieu via Varese, Morosini,Stazione FS FN, Varese, Rho Fiera Milano, Rho-Fiera Milano, and Torino Porta Susa in around 7h 36m.
- Website
- twinjet.fr
Flights from Milano Malpensa Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h
- When
- Monday to Friday
- Estimated price
- €480–1,200
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- Trenord
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 58 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 58 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Varese to Malpensa Aeroporto T1
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €4–5
- Website
- Trenord
Train from Varese to Milano Porta Garibaldi
- Ave. Duration
- 1h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €5–7
- Website
- Trenord
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 37 min
- Frequency
- 4 times a week
- Estimated price
- €17–25
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 37 min
- Frequency
- 4 times a week
- Estimated price
- €17–25
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Varese to Malpensa Aeroporto T1
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €15–21
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Varese to Milano Porta Garibaldi
- Ave. Duration
- 47 min
- Frequency
- 4 times a week
- Estimated price
- €21–30
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Rho-Fiera Milano to Torino Porta Susa
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- €18–30
- Website
- Trenitalia Frecce
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Rho-Fiera Milano to Torino Porta Susa
- Ave. Duration
- 1h 29m
- Frequency
- Every 30 minutes
- Estimated price
- €15–22
- Website
- Trenitalia
Train from Torino Porta Susa to Lyon Part Dieu
- Ave. Duration
- 3h 52m
- Frequency
- 4 times a day
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Chambery Challes Les Eaux to Lyon Part Dieu
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Estimated price
- €12–18
- Website
- Trenitalia
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Rho-Fiera Milano to Torino Porta Susa
- Ave. Duration
- 1h 7m
- Frequency
- Every 2 hours
- Estimated price
- €15–25
- Website
- Italo Treno
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Milano P.Garibaldi to Chambery Challes Les Eaux
- Ave. Duration
- 4h 9m
- Frequency
- Every 4 hours
- Estimated price
- €65–100
- Website
- TGV inOui
Train from Chambery Challes Les Eaux to Lyon Part Dieu
- Ave. Duration
- 1h 23m
- Frequency
- 4 times a week
- Estimated price
- €21–35
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Chambery Challes Les Eaux to Lyon Part Dieu
- Ave. Duration
- 1h 26m
- Frequency
- Hourly
- Estimated price
- €18–35
- Website
- Oui.SNCF
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Milan Lampugnano to Lyon Lyon Perrache Bus Station
- Ave. Duration
- 6h 35m
- Frequency
- 3 times a day
- Estimated price
- €23–40
- Website
- Itabus S.p.A.
Bus from Milan to Turin
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- €6–12
- Website
- Itabus S.p.A.
- Phone
- +39 0332 731110
- info@autolineevaresine.it
- Website
- Autolinee Varesine Srl
Bus from Ispra, Mazzini/Roma,distributore to Varese, Morosini,Stazione FS FN
- Ave. Duration
- 43 min
- Frequency
- Hourly
- Estimated price
- €3–5
- Schedules at
- Autolinee Varesine Srl
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Milan to Turin
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Estimated price
- €10–16
- Website
- Flixbus
Bus from Turin to Lyon
- Ave. Duration
- 4h 10m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Turin to Lyon
- Ave. Duration
- 5h 20m
- Frequency
- Every 3 hours
- Estimated price
- €22–40
- Website
- BlaBlaCar Bus
- Phone
- +39 0322 233 200
- infomaggiore@navigazionelaghi.it
- Website
- Gestione Governativa Navigazione Laghi
Ferry from Angera to Arona
- Ave. Duration
- 10 min
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- Gestione Governativa Navigazione Laghi
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Italian Lakes: Getting around by train
Read the travel guide
Italy Travel Guides
Read the travel guide


















































