There are 7 ways to get from Ispra to Lyon by train (Trenitalia), bus, car, train, plane, ferry, or train (TGV, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Varese to Rho Fiera Milanotrain S5 / ...
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
8h 2m€60–144Train, bus
cheapest- Take the train from Varese to Malpensa Aeroporto T2train S50
- Take the bus from Milan to Turinbus 467 / ...
- Take the bus from Turin - Vittorio Emanuele Bus Station to Lyon - Gerland Bus Stationbus
9h 26m€36–114Bus
- Take the bus from Sesto Calende to Rho Fiera Milanobus Re4 / ...
- Take the bus from Milano, Autostazione Lampugnano to Lyon - Gerland Bus Stationbus BlaBlaCar Bus
8h 25mDrive 431.5 km
- Drive from Ispra to Lyoncar 431.5 km
4h 37m€67–97Bus, train, fly
- Take the bus from Ispra, Mazzini/Roma,distributore to Varese, Morosini,Stazione FS FNbus
- Take the train from Varese to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Lyon–Saint Exupéry Airport (LYS)plane MXP - LYS
5h 30mFerry, train
- Take the ferry from Angera to Aronaferry 37 / ...
- Take the train from Novara to Torino Porta Susatrain
- Take the train from Torino Porta Susa to Lyon Part Dieutrain Fr
8h 40m€54–99Train via Chambéry
- Take the train from Varese to Milano Porta Garibalditrain S5 / ...
- Take the train from Milano P.Garibaldi to Chambery Challes Les Eauxtrain Tgv
- Take the train from Chambery Challes Les Eaux to Lyon Part Dieutrain Ter
9h 2m€83–205
Ispra to Lyon by bus and train
Questions & Answers
The cheapest way to get from Ispra to Lyon is to train and bus which costs €35 - €120 and takes 9h 26m.
The fastest way to get from Ispra to Lyon is to drive which takes 4h 37m and costs €65 - €100.
No, there is no direct bus from Ispra to Lyon station. However, there are services departing from Ispra and arriving at Lyon - Gerland Bus Station via Sesto Calende and Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 8h 25m.
No, there is no direct train from Ispra to Lyon. However, there are services departing from Varese and arriving at Lyon Part Dieu via Rho-Fiera Milano and Milano Centrale. The journey, including transfers, takes approximately 8h 2m.
The distance between Ispra and Lyon is 531 km. The road distance is 431.5 km.
The best way to get from Ispra to Lyon without a car is to train which takes 8h 2m and costs €60 - €150.
It takes approximately 8h 2m to get from Ispra to Lyon, including transfers.
Ispra to Lyon bus services, operated by Trenord, depart from Sesto Calende station.
Ispra to Lyon train services, operated by Trenord, depart from Varese station.
The best way to get from Ispra to Lyon is to train which takes 8h 2m and costs €60 - €150. Alternatively, you can bus, which costs and takes 8h 25m.
What companies run services between Ispra, Italy and Lyon, France?
You can take a bus from Ispra, Mazzini/Roma,distributore to Lyon Part Dieu via Varese, Morosini,Stazione FS FN, Varese, Rho Fiera Milano, Rho-Fiera Milano, and Milano Centrale in around 8h 2m. Alternatively, you can take a bus from Ispra to Lyon - Gerland Bus Station via Sesto Calende, Rho Fiera Milano, Rho Fieramilano, Lampugnano, and Milano, Autostazione Lampugnano in around 8h 25m.
- Website
- twinjet.fr
Flights from Milano Malpensa Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h
- When
- Monday to Friday
- Estimated price
- €500–750
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- Trenord
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 58 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Varese to Malpensa Aeroporto T1
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €4–5
- Website
- Trenord
Train from Varese to Milano Porta Garibaldi
- Ave. Duration
- 1h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €5–7
- Website
- Trenord
Train from Varese to Malpensa Aeroporto T2
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- Trenord
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 37 min
- Frequency
- 4 times a week
- Estimated price
- €17–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Varese to Malpensa Aeroporto T1
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €14–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Varese to Milano Porta Garibaldi
- Ave. Duration
- 47 min
- Frequency
- 4 times a week
- Estimated price
- €20–60
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Varese to Malpensa Aeroporto T2
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €15–50
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 39m
- Frequency
- 4 times a day
- Estimated price
- €55–90
- Website
- Trenitalia
Train from Novara to Torino Porta Susa
- Ave. Duration
- 58 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–20
- Website
- Trenitalia
Train from Torino Porta Susa to Lyon Part Dieu
- Ave. Duration
- 3h 52m
- Frequency
- 4 times a day
- Estimated price
- €35–65
- Website
- Trenitalia
Train from Chambery Challes Les Eaux to Lyon Part Dieu
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Estimated price
- €13–22
- Website
- Trenitalia
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Milano P.Garibaldi to Chambery Challes Les Eaux
- Ave. Duration
- 4h 7m
- Frequency
- Every 4 hours
- Estimated price
- €65–110
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Chambery Challes Les Eaux to Lyon Part Dieu
- Ave. Duration
- 1h 26m
- Frequency
- Hourly
- Estimated price
- €17–35
- Website
- Oui.SNCF
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- Trenord
Bus from Sesto Calende to Rho Fiera Milano
- Ave. Duration
- 38 min
- Frequency
- Hourly
- Website
- Trenord
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Milano, Autostazione Lampugnano to Lyon - Gerland Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Hourly
- Estimated price
- €35–70
- Website
- BlaBlaCar Bus
Bus from Turin - Vittorio Emanuele Bus Station to Lyon - Gerland Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- Hourly
- Estimated price
- €26–50
- Website
- BlaBlaCar Bus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Lyon - Gerland Bus Station
- Ave. Duration
- 7h 10m
- Frequency
- Every 3 hours
- Estimated price
- €35–60
- Website
- Flixbus
Bus from Milan to Turin
- Ave. Duration
- 2h
- Frequency
- Every 2 hours
- Estimated price
- €10–17
- Website
- Flixbus
Bus from Turin - Vittorio Emanuele Bus Station to Lyon - Gerland Bus Station
- Ave. Duration
- 5h 25m
- Frequency
- Hourly
- Estimated price
- €24–40
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Milano, Autostazione Lampugnano to Lyon - Gerland Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- 4 times a day
- Estimated price
- €27–60
- Website
- Itabus S.p.A.
Bus from Milan to Turin
- Ave. Duration
- 2h 10m
- Frequency
- Twice daily
- Estimated price
- €8–17
- Website
- Itabus S.p.A.
- Phone
- +39 0332 731110
- info@autolineevaresine.it
- Website
- Autolinee Varesine Srl
Bus from Ispra, Mazzini/Roma,distributore to Varese, Morosini,Stazione FS FN
- Ave. Duration
- 43 min
- Frequency
- Hourly
- Schedules at
- Autolinee Varesine Srl
- Phone
- +39 0322 233 200
- infomaggiore@navigazionelaghi.it
- Website
- Gestione Governativa Navigazione Laghi
Ferry from Angera to Arona
- Ave. Duration
- 10 min
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- Gestione Governativa Navigazione Laghi
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Italian Lakes: Getting around by train
Read the travel guide
Italy Travel Guides
Read the travel guide
More Questions & Answers
Ispra to Lyon bus services, operated by Trenord, arrive at Rho Fiera Milano station.
Ispra to Lyon train services, operated by Trenord, arrive at Rho Fiera Milano station.
Yes, the driving distance between Ispra to Lyon is 431 km. It takes approximately 4h 37m to drive from Ispra to Lyon.
There are 4086+ hotels available in Lyon.







































