There are 4 ways to get from Isla Mujeres to Key Largo by ferry, plane, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry to Cancún International Airport, fly to Miami International Airport, shuttle
best- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Fly from Cancún International Airport (CUN) to Miami International Airport (MIA)plane CUN - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 31m$333–701Ferry to Cancún International Airport, fly to Key West International Airport, bus
cheapest- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Fly from Cancún International Airport (CUN) to Key West International Airport (EYW)plane CUN - EYW
- Take the bus from Key West Airport to Key Largo Bus Stopbus
11h 43m$105–408Ferry to Cancún International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Fly from Cancún International Airport (CUN) to Fort Lauderdale–Hollywood International Airport (FLL)plane CUN - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
7h 59m$223–631Ferry, bus, ferry to Cozumel International Airport, fly to Miami International Airport, shuttle
- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Take the bus from Terminal de Autobuses ADO Cancún to Playa del Carmen Terminal Turísticabus
- Take the ferry from Playa del Carmen to Cozumelferry
- Fly from Cozumel International Airport (CZM) to Miami International Airport (MIA)plane CZM - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
10h 9m$215–697
Cancún International Airport (CUN) to Miami International Airport (MIA) flights
Comparing Your Travel Options
The cheapest way to get from Isla Mujeres to Key Largo is to ferry and fly and bus which costs $100 - $410 and takes 11h 43m.
The fastest way to get from Isla Mujeres to Key Largo is to ferry and fly and shuttle which takes 7h 31m and costs $330 - $700.
The distance between Isla Mujeres and Key Largo is 627 miles.
It takes approximately 7h 31m to get from Isla Mujeres to Key Largo, including transfers.
There are 346+ hotels available in Key Largo.
What companies run services between Isla Mujeres, Mexico and Key Largo, FL, USA?
There is no direct connection from Isla Mujeres to Key Largo. However, you can take the ferry to Playa Tortugas, walk to Playa Tortugas, take the shuttle to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to Miami International Airport (MIA), walk to Miami, FL - International Airport, then take the shuttle to Key Largo, FL. Alternatively, you can take the ferry to Playa Tortugas, walk to Playa Tortugas, take the shuttle to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to Fort Lauderdale–Hollywood International Airport (FLL), walk to Fort Lauderdale, FL - International Airport, then take the shuttle to Key Largo, FL.
- Website
- aa.com
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $50–320
Flights from Cancún International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 4h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $55–310
Flights from Cozumel International Airport to Miami International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $85–490
- Website
- delta.com
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 2h 2m
- When
- Tuesday and Wednesday
- Estimated price
- $50–320
Flights from Cancún International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $95–430
- Website
- aeromexico.com
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 2h 2m
- When
- Tuesday and Wednesday
- Estimated price
- $50–320
Flights from Cancún International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h
- When
- Saturday
- Estimated price
- $95–430
- Website
- jetblue.com
Flights from Cancún International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $70–410
- Website
- latam.com
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 55m
- When
- Sunday
- Estimated price
- $110–420
- Website
- united.com
Flights from Cancún International Airport to Key West International Airport via Houston
- Ave. Duration
- 7h 3m
- When
- Saturday
- Estimated price
- $100–460
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Key West Airport to Key Largo Bus Stop
- Ave. Duration
- 2h 50m
- Frequency
- 3 times a day
- Estimated price
- $17–27
- Website
- Greyhound
- Phone
- +52 55 4386 4652
- solucioneshola@ado.com.mx
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Playa del Carmen Terminal Turística
- Ave. Duration
- 1h 20m
- Frequency
- Every 30 minutes
- Estimated price
- $10–16
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 997 976 0191
- solucioneshola@ado.com.mx
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Playa del Carmen Terminal Turística
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- $4–6
- Schedules at
- ahorrobus.com.mx
- Phone
- +52 998 460 3084
- servicioalcliente@ultramarferry.com
- Website
- Ultramar Ferry
Ferry from Isla Mujeres to Playa Tortugas
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $12–17
- Website
- Ultramar Ferry
- Premium Plus
- $15–17
- Adult
- $16
- Child
- $12
Ferry from Isla Mujeres to Playa Tortugas
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $12–17
- Website
- Ultramar Ferry
- Premium Plus
- $15–17
- Adult
- $16
- Child
- $12
Ferry from Isla Mujeres to Playa Tortugas
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $12–17
- Website
- Ultramar Ferry
- Premium Plus
- $15–17
- Adult
- $16
- Child
- $12
Ferry from Isla Mujeres to Playa Tortugas
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $12–17
- Website
- Ultramar Ferry
- Premium Plus
- $15–17
- Adult
- $16
- Child
- $12
Ferry from Playa del Carmen to Cozumel
- Ave. Duration
- 40 min
- Frequency
- Every 3 hours
- Estimated price
- $6–21
- Website
- Ultramar Ferry
- Premium Plus
- $15–17
- Premium Plus Adult
- $17
- Premium Plus Children
- $13
- Residentes Q.Roo
- $11
- INAPAM
- $6
- First Class Adult
- $21
- First Class Children
- $21
- Phone
- +52 987 872 1508
- info@winjet.mx
- Website
- winjet.mx
Ferry from Playa del Carmen to Cozumel
- General
- $19
- Handicapped
- $6
- Minor
- $14
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide





























