There are 11 ways to get from Isesaki to Osaka by train, bus, car, subway or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  5 h 27 min

  1. Take the train from Takasaki to Tokyo JR Takasaki / ...
  2. Take the train from Tokyo to Shin-Osaka Shinkansen Nozomi / ...

$121 - $179

Cheapest option

Bus  •  11 h 13 min

  1. Take the bus from Isesaki City Hall to Basuta Shinjuku
  2. Take the bus from Buster Shinjuku to Osaka Station Bus Terminal

$59

9 alternative options

Train via Kanazawa  •  7 h 10 min

  1. Take the train from Takasaki to Kanazawa Shinkansen Hakutaka
  2. Take the train from Kanazawa to Osaka Ltd Exp Thunderbird

$142 - $182

Train, bus  •  11 h 39 min

  1. Take the train from Takasaki to Nagano
  2. Take the bus from Nagano to Fukakusa Kyoto
  3. Take the train from Fukakusa to Yodoyabashi

$101 - $124

Drive  •  6 h 24 min

  1. Drive from Isesaki to Osaka 370.4 miles

$60 - $90

Train, subway to Tokyo Haneda, fly to Osaka  •  5 h 56 min

  1. Take the train from Shin-Isesaki to Ota(Gunma)
  2. Take the train from Ota(Gunma) to Tokyo Skytree
  3. Take the subway from Oshiage to Daimon(Tokyo)
  4. Fly from Tokyo Haneda (HND) to Osaka (ITM) HND - ITM

$96 - $340

Train, subway to Tokyo Haneda, fly to Osaka Kobe  •  6 h 27 min

  1. Take the train from Shin-Isesaki to Ota(Gunma)
  2. Take the train from Ota(Gunma) to Tokyo Skytree
  3. Take the subway from Oshiage to Daimon(Tokyo)
  4. Fly from Tokyo Haneda (HND) to Osaka Kobe (UKB) HND - UKB
  5. Take the train from Sannomiya(Jr) to Osaka

$86 - $288

Train, train to Tokyo Narita, fly to Osaka  •  6 h 45 min

  1. Take the train from Takasaki to Tokyo
  2. Take the train from Tokyo to Narita Airport Terminal 2
  3. Fly from Tokyo Narita (NRT) to Osaka (ITM) NRT - ITM

$142 - $485

Train, train to Niigata, fly to Osaka  •  5 h 47 min

  1. Take the train from Isesaki to Takasaki
  2. Take the train from Takasaki to Niigata
  3. Fly from Niigata (KIJ) to Osaka (ITM) KIJ - ITM

$164 - $322

Train, train to Ibaraki, fly to Osaka Kobe  •  6 h 52 min

  1. Take the train from Isesaki to Oyama(Tochigi)
  2. Take the train from Oyama(Tochigi) to Tomobe
  3. Fly from Ibaraki (IBR) to Osaka Kobe (UKB) IBR - UKB

$126 - $301

Train, train to Fukushima, fly to Osaka  •  7 h 4 min

  1. Take the train from Isesaki to Oyama(Tochigi)
  2. Take the train from Oyama(Tochigi) to Shin-Shirakawa
  3. Fly from Fukushima (FKS) to Osaka (ITM) FKS - ITM

$204 - $362

Questions & Answers

No, there is no direct bus from Isesaki to Osaka station. However, there are services departing from Isesaki City Hall and arriving at Osaka Station Bus Terminal via Buster Shinjuku. The journey, including transfers, takes approximately 11 h 13 min.

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No, there is no direct train from Isesaki to Osaka. However, there are services departing from Isesaki and arriving at Osaka via Takasaki and Kanazawa. The journey, including transfers, takes approximately 7 h 10 min.

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The distance between Isesaki and Osaka is 380 km. The road distance is 592.7 km.

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The best way to get from Isesaki to Osaka without a car is to train which takes 5 h 27 min and costs .

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It takes approximately 5 h 27 min to get from Isesaki to Osaka, including transfers.

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Isesaki to Osaka bus services, operated by JR Bus Kanto, depart from Isesaki City Hall station.

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Isesaki to Osaka train services, operated by Japan Railways Shinkansen, depart from Takasaki station.

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The best way to get from Isesaki to Osaka is to train which takes 5 h 27 min and costs . Alternatively, you can bus, which costs and takes 11 h 13 min.

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The quickest flight from Tokyo Haneda Airport to Osaka Airport is the direct flight which takes 1 h 5 min.

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Isesaki to Osaka bus services, operated by JR Bus Kanto, arrive at Osaka Station Bus Terminal.

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Map of how to get from Isesaki to Osaka.
Launch map view
  • Distance: 237.6 miles
  • Duration: 5 h 27 min

What companies run services between Isesaki, Japan and Osaka, Japan?

You can take a train from Isesaki to Osaka via Takasaki, Tokyo, and Shin-Osaka in around 5 h 27 min. Alternatively, you can take a bus from Isesaki to Osaka via Basuta Shinjuku and Buster Shinjuku in around 11 h 13 min.

Airlines
All Nippon Airways
Website
ana.co.jp
Flights from Tokyo Haneda to Osaka
Ave. Duration
1 h 7 min
When
Every day
Estimated price
$80 - $440
Flights from Tokyo Haneda to Osaka Kobe
Ave. Duration
1 h 12 min
When
Every day
Estimated price
$85 - $450
Flights from Tokyo Narita to Osaka
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$110 - $650
Flights from Niigata to Osaka
Ave. Duration
1 h 8 min
When
Every day
Estimated price
$100 - $320
Flights from Fukushima to Osaka
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$100 - $330
Japan Airlines
Website
jal.com
Flights from Tokyo Haneda to Osaka
Ave. Duration
1 h 6 min
When
Every day
Estimated price
$85 - $470
Flights from Tokyo Narita to Osaka
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$110 - $750
Flights from Tokyo Narita to Osaka via Matsuyama
Ave. Duration
3 h 35 min
When
Every day
Estimated price
$65 - $410
Flights from Niigata to Osaka
Ave. Duration
1 h 7 min
When
Every day
Estimated price
$90 - $400
Skymark Airlines
Website
skymark.co.jp
Flights from Tokyo Haneda to Osaka Kobe
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$60 - $270
Flights from Ibaraki to Osaka Kobe
Ave. Duration
1 h 12 min
When
Every day
Estimated price
$50 - $320
Ibex Airlines
Website
ibexair.co.jp
Flights from Niigata to Osaka
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$110 - $240
Flights from Fukushima to Osaka
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$120 - $240
Train operators
Japan Railways (JR)

Japan Railways operates a large proportion of the main intercity routes, including the high-speed Shinkansen service and commuter rail service. Covering 1665 stations across 7458km, Japan Railways carries an average of 17 million passengers per day. There are several rail passes on offer for customers such as the Hokkaido Pass, the JR West Rail Pass, JR East Pass, Shikoku Pass, Kyushu Pass and Flex Japan Tourist Pass.

Contact Details
Website
hyperdia.com
Train from Takasaki to Tokyo
Ave. Duration
1 h 55 min
Frequency
Every 20 minutes
Estimated price
$15 - $21
Schedules at
hyperdia.com
Train from Sannomiya(Jr) to Osaka
Ave. Duration
37 min
Frequency
Every 10 minutes
Estimated price
$4 - $7
Schedules at
hyperdia.com
Train from Isesaki to Takasaki
Ave. Duration
30 min
Frequency
Every 30 minutes
Estimated price
$3 - $5
Schedules at
hyperdia.com
Train from Isesaki to Oyama(Tochigi)
Ave. Duration
1 h 20 min
Frequency
Hourly
Estimated price
$10 - $14
Schedules at
hyperdia.com
Train from Oyama(Tochigi) to Tomobe
Ave. Duration
1 h 7 min
Frequency
Hourly
Estimated price
$7 - $11
Schedules at
hyperdia.com
Japan Railways Shinkansen
Website
hyperdia.com
Train from Tokyo to Shin-Osaka
Ave. Duration
2 h 33 min
Frequency
Every 15 minutes
Estimated price
$100 - $150
Schedules at
hyperdia.com
Unreserved seat
$100 - $150
Reserved seat
$120 - $150
Green seat
$150 - $210
Train from Takasaki to Kanazawa
Ave. Duration
2 h 16 min
Frequency
Every 2 hours
Estimated price
$75 - $110
Schedules at
hyperdia.com
Unreserved seat
$75 - $100
Reserved seat
$85 - $110
Green seat
$110 - $150
Train from Takasaki to Nagano
Ave. Duration
47 min
Frequency
Hourly
Estimated price
$30 - $50
Schedules at
hyperdia.com
Unreserved seat
$30 - $45
Reserved seat
$40 - $50
Green seat
$50 - $70
Train from Takasaki to Niigata
Ave. Duration
1 h 17 min
Frequency
Hourly
Estimated price
$45 - $70
Schedules at
hyperdia.com
Unreserved seat
$45 - $65
Reserved seat
$55 - $70
Green seat
$70 - $95
Train from Oyama(Tochigi) to Shin-Shirakawa
Ave. Duration
42 min
Frequency
Every 2 hours
Estimated price
$30 - $50
Schedules at
hyperdia.com
Unreserved seat
$30 - $45
Reserved seat
$35 - $50
Green seat
$45 - $65
Japan Railways Thunderbird
Website
hyperdia.com
Train from Kanazawa to Osaka
Ave. Duration
2 h 48 min
Frequency
Hourly
Estimated price
$63 - $67
Schedules at
hyperdia.com
Keihan Railways
Website
hyperdia.com
Train from Fukakusa to Yodoyabashi
Ave. Duration
1 h 13 min
Frequency
Every 30 minutes
Estimated price
$4 - $6
Schedules at
hyperdia.com
Tobu Railway
Website
hyperdia.com
Train from Shin-Isesaki to Ota(Gunma)
Ave. Duration
23 min
Frequency
Every 30 minutes
Estimated price
$2 - $4
Schedules at
hyperdia.com
Train from Ota(Gunma) to Tokyo Skytree
Ave. Duration
1 h 18 min
Frequency
Hourly
Estimated price
$10 - $13
Schedules at
hyperdia.com
Bus operators
JR Bus Kanto
Website
jrbuskanto.co.jp.e.wn.hp.transer.com
Bus from Isesaki City Hall to Basuta Shinjuku
Ave. Duration
2 h 3 min
Frequency
Every 4 hours
Estimated price
$14
Schedules at
time.jrbuskanto.co.jp.e.wn.hp.transer.com
Bus from Buster Shinjuku to Osaka Station Bus Terminal
Ave. Duration
8 h 10 min
Frequency
5 times a day
Estimated price
$45
Schedules at
time.jrbuskanto.co.jp.e.wn.hp.transer.com
Access Shinshu
Website
alpico.co.jp
Bus from Nagano to Fukakusa Kyoto
Ave. Duration
7 h 29 min
Frequency
Twice daily
Estimated price
$63
Schedules at
alpico.co.jp

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More Questions & Answers

Isesaki to Osaka train services, operated by Japan Railways Thunderbird, arrive at Osaka station.

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Yes, the driving distance between Isesaki to Osaka is 593 km. It takes approximately 6 h 24 min to drive from Isesaki to Osaka.

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Japan Airlines and All Nippon Airways offer flights from Tokyo Haneda Airport to Osaka Airport.

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There are 2568+ hotels available in Osaka. Prices start at $48 USD per night.

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