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There are 11 ways to get from Isesaki to Osaka by train, bus, night bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  5h 26m

  1. Take the train from Takasaki to Tokyo JR Takasaki / ...
  2. Take the train from Tokyo to Shin-Osaka Shinkansen Nozomi / ...

$120 - $179

Cheapest option

Bus  •  12h 20m

  1. Take the bus from Isesaki Sta.(South Ent.) to 大阪ocat [Highway Bus] Silk Liner

$60 - $110

9 alternative options

Train via Kanazawa  •  7h 6m

  1. Take the train from Takasaki to Kanazawa Shinkansen Hakutaka
  2. Take the train from Kanazawa to Osaka Ltd Exp Thunderbird

$140 - $182

Night bus  •  13h 8m

  1. Take the night bus from Karuizawa Station to Ōsaka

$110 - $127

Drive  •  6h 24m

  1. Drive from Isesaki to Osaka 370.4 miles

$60 - $90

Train to Tokyo Haneda, fly to Osaka Itami  •  5h 52m

  1. Take the train from Takasaki to Tokyo
  2. Fly from Tokyo Haneda (HND) to Osaka Itami (ITM) HND - ITM

$100 - $349

Train, train to Tokyo Haneda, fly to Kobe  •  6h 34m

  1. Take the train from Isesaki to Takasaki
  2. Take the train from Takasaki to Tokyo
  3. Fly from Tokyo Haneda (HND) to Kobe (UKB) HND - UKB
  4. Take the train from Kobe-Sannomiya(Hankyu) to Umeda(Hankyu)

$89 - $294

Train, train to Tokyo Narita, fly to Osaka Itami  •  6h 45m

  1. Take the train from Takasaki to Tokyo
  2. Take the train from Tokyo to Narita Airport Terminal 2
  3. Fly from Tokyo Narita (NRT) to Osaka Itami (ITM) NRT - ITM

$141 - $485

Train, train to Niigata, fly to Osaka Itami  •  5h 48m

  1. Take the train from Isesaki to Takasaki
  2. Take the train from Takasaki to Niigata
  3. Fly from Niigata (KIJ) to Osaka Itami (ITM) KIJ - ITM

$160 - $322

Train, train to Ibaraki, fly to Kobe  •  7h 2m

  1. Take the train from Isesaki to Oyama(Tochigi)
  2. Take the train from Oyama(Tochigi) to Tomobe
  3. Fly from Ibaraki (IBR) to Kobe (UKB) IBR - UKB

$125 - $298

Train, train to Fukushima, fly to Osaka Itami  •  6h 54m

  1. Take the train from Isesaki to Oyama(Tochigi)
  2. Take the train from Oyama(Tochigi) to Shin-Shirakawa
  3. Fly from Fukushima (FKS) to Osaka Itami (ITM) FKS - ITM

$204 - $362

Questions & Answers

The cheapest way to get from Isesaki to Osaka is to drive which costs ¥7000 - ¥11000 and takes 6h 24m.

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The quickest way to get from Isesaki to Osaka is to train which costs ¥13000 - ¥21000 and takes 5h 26m.

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Yes, there is a direct bus departing from Isesaki Sta.(South Ent.) and arriving at 大阪ocat. Services depart twice daily, and operate every day. The journey takes approximately 12h 20m.

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No, there is no direct train from Isesaki to Osaka. However, there are services departing from Isesaki and arriving at Osaka via Takasaki and Kanazawa. The journey, including transfers, takes approximately 7h 6m.

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The distance between Isesaki and Osaka is 380 km. The road distance is 592.7 km.

Get driving directions

The best way to get from Isesaki to Osaka without a car is to train which takes 5h 26m and costs ¥13000 - ¥21000.

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It takes approximately 5h 26m to get from Isesaki to Osaka, including transfers.

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Isesaki to Osaka bus services, operated by Nippon Chuo Bus Co, depart from Isesaki Sta.(South Ent.) station.

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Isesaki to Osaka train services, operated by Japan Railways Shinkansen, depart from Takasaki station.

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The best way to get from Isesaki to Osaka is to train which takes 5h 26m and costs ¥13000 - ¥21000. Alternatively, you can bus, which costs ¥7000 - ¥12000 and takes 12h 20m.

Mode details

Map of how to get from Isesaki to Osaka.
Launch map view
  • Distance: 237.6 miles
  • Duration: 5h 26m

What companies run services between Isesaki, Japan and Osaka, Japan?

You can take a train from Isesaki to Osaka via Takasaki, Tokyo, Shin-Osaka, and Shin-Osaka in around 5h 26m. Alternatively, Nippon Chuo Bus Co operates a bus from Isesaki to Osaka twice daily. Tickets cost $60 - $110 and the journey takes 12h 20m.

Airlines
All Nippon Airways
Website
ana.co.jp
Flights from Tokyo Haneda to Osaka Itami
Ave. Duration
1h 10m
When
Every day
Estimated price
$80 - $440
Flights from Tokyo Haneda to Kobe
Ave. Duration
1h 15m
When
Every day
Estimated price
$85 - $450
Flights from Tokyo Narita to Osaka Itami
Ave. Duration
1h 27m
When
Every day
Estimated price
$110 - $650
Flights from Tokyo Narita to Osaka Itami via Sendai
Ave. Duration
3h 15m
When
Every day
Estimated price
$220 - $310
Flights from Niigata to Osaka Itami
Ave. Duration
1h 11m
When
Every day
Estimated price
$100 - $320
Flights from Fukushima to Osaka Itami
Ave. Duration
1h 15m
When
Every day
Estimated price
$100 - $330
Japan Airlines
Website
jal.com
Flights from Tokyo Haneda to Osaka Itami
Ave. Duration
1h 11m
When
Every day
Estimated price
$85 - $470
Flights from Tokyo Narita to Osaka Itami
Ave. Duration
1h 27m
When
Every day
Estimated price
$110 - $750
Flights from Niigata to Osaka Itami
Ave. Duration
1h 12m
When
Every day
Estimated price
$90 - $400
Skymark Airlines
Website
skymark.co.jp
Flights from Tokyo Haneda to Kobe
Ave. Duration
1h 19m
When
Every day
Estimated price
$60 - $270
Flights from Ibaraki to Kobe
Ave. Duration
1h 17m
When
Every day
Estimated price
$50 - $320
Ibex Airlines
Website
ibexair.co.jp
Flights from Niigata to Osaka Itami
Ave. Duration
1h 10m
When
Every day
Estimated price
$110 - $240
Flights from Fukushima to Osaka Itami
Ave. Duration
1h 15m
When
Every day
Estimated price
$120 - $240
Train operators
Japan Railways (JR)

Japan Railways operates a large proportion of the main intercity routes, including the high-speed Shinkansen service and commuter rail service. Covering 1665 stations across 7458km, Japan Railways carries an average of 17 million passengers per day. There are several rail passes on offer for customers such as the Hokkaido Pass, the JR West Rail Pass, JR East Pass, Shikoku Pass, Kyushu Pass and Flex Japan Tourist Pass.

Contact Details
Website
hyperdia.com
Train from Takasaki to Tokyo
Ave. Duration
1h 55m
Frequency
Every 15 minutes
Estimated price
$15 - $21
Schedules at
hyperdia.com
Train from Isesaki to Takasaki
Ave. Duration
30m
Frequency
Every 30 minutes
Estimated price
$3 - $5
Schedules at
hyperdia.com
Train from Isesaki to Oyama(Tochigi)
Ave. Duration
1h 20m
Frequency
Hourly
Estimated price
$9 - $14
Schedules at
hyperdia.com
Train from Oyama(Tochigi) to Tomobe
Ave. Duration
1h 7m
Frequency
Hourly
Estimated price
$7 - $11
Schedules at
hyperdia.com
Japan Railways Shinkansen
Website
hyperdia.com
Train from Tokyo to Shin-Osaka
Ave. Duration
2h 33m
Frequency
Every 15 minutes
Estimated price
$100 - $150
Schedules at
hyperdia.com
Unreserved seat
$100 - $150
Reserved seat
$120 - $150
Green seat
$150 - $200
Train from Takasaki to Kanazawa
Ave. Duration
2h 16m
Frequency
Every 2 hours
Estimated price
$75 - $110
Schedules at
hyperdia.com
Unreserved seat
$75 - $100
Reserved seat
$85 - $110
Green seat
$110 - $150
Train from Takasaki to Niigata
Ave. Duration
1h 17m
Frequency
Hourly
Estimated price
$45 - $70
Schedules at
hyperdia.com
Unreserved seat
$45 - $65
Reserved seat
$55 - $70
Green seat
$70 - $95
Train from Oyama(Tochigi) to Shin-Shirakawa
Ave. Duration
42m
Frequency
Hourly
Estimated price
$30 - $50
Schedules at
hyperdia.com
Unreserved seat
$30 - $45
Reserved seat
$35 - $50
Green seat
$45 - $65
Japan Railways Thunderbird
Website
hyperdia.com
Train from Kanazawa to Osaka
Ave. Duration
2h 48m
Frequency
Hourly
Estimated price
$62 - $67
Schedules at
hyperdia.com
Hankyu Railways
Website
hankyu.co.jp
Train from Kobe-Sannomiya(Hankyu) to Umeda(Hankyu)
Ave. Duration
43m
Frequency
Every 10 minutes
Estimated price
$3 - $4
Schedules at
hyperdia.com
Bus operators
Nippon Chuo Bus Co
Website
ncbbus.co.jp
Bus from Isesaki Sta.(South Ent.) to 大阪ocat
Ave. Duration
12h 20m
Frequency
Twice daily
Estimated price
$60 - $110
Schedules at
ncbbus.co.jp
Kintetsu Bus
Phone
06-6618-5301
Website
kintetsu-bus.co.jp
Night bus from Karuizawa Station to Ōsaka
Ave. Duration
10h 55m
Frequency
Once daily
Estimated price
$87
Schedules at
kintetsu-bus.co.jp

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More Questions & Answers

The quickest flight from Tokyo Haneda Airport to Osaka Itami Airport is the direct flight which takes 1h 5m.

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Isesaki to Osaka bus services, operated by Nippon Chuo Bus Co, arrive at 大阪ocat station.

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Isesaki to Osaka train services, operated by Japan Railways Thunderbird, arrive at Osaka station.

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Yes, the driving distance between Isesaki to Osaka is 593 km. It takes approximately 6h 24m to drive from Isesaki to Osaka.

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All Nippon Airways and Japan Airlines offer flights from Tokyo Haneda Airport to Osaka Itami Airport.

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There are 3288+ hotels available in Osaka. Prices start at $47 USD per night.

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