What is the cheapest way to get from Isernia to Siena?

The cheapest way to get from Isernia to Siena is to bus which costs €20 - €50 and takes 5h 14m.

What is the fastest way to get from Isernia to Siena?

The fastest way to get from Isernia to Siena is to drive which takes 3h 57m and costs €60 - €90.

Is there a direct bus between Isernia and Siena?

No, there is no direct bus from Isernia to Siena. However, there are services departing from Isernia and arriving at Siena via Roma. The journey, including transfers, takes approximately 5h 14m.

Is there a direct train between Isernia and Siena?

No, there is no direct train from Isernia to Siena. However, there are services departing from Isernia and arriving at Siena via Roma Termini and Chiusi-Chianciano T.. The journey, including transfers, takes approximately 7h 36m.

How far is it from Isernia to Siena?

The distance between Isernia and Siena is 404 km. The road distance is 388.1 km.

How do I travel from Isernia to Siena without a car?

The best way to get from Isernia to Siena without a car is to bus which takes 5h 14m and costs €20 - €50.

How long does it take to get from Isernia to Siena?

It takes approximately 5h 14m to get from Isernia to Siena, including transfers.

Where do I catch the Isernia to Siena bus from?

Isernia to Siena bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., depart from Isernia station.

Where do I catch the Isernia to Siena train from?

Isernia to Siena train services, operated by Trenitalia, depart from Isernia station.

Train or bus from Isernia to Siena?

The best way to get from Isernia to Siena is to bus which takes 5h 14m and costs €20 - €50. Alternatively, you can train, which costs €45 - €95 and takes 7h 36m.

Where does the Isernia to Siena bus arrive?

Isernia to Siena bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., arrive at Roma, Autostazione Tiburtina station.

Where does the Isernia to Siena train arrive?

Isernia to Siena train services, operated by Trenitalia, arrive at Roma Termini station.

Can I drive from Isernia to Siena?

Yes, the driving distance between Isernia to Siena is 388 km. It takes approximately 3h 57m to drive from Isernia to Siena.

How do I get a train ticket from Isernia to Siena?

Book your Isernia to Siena train tickets online with Omio.

How do I get a bus ticket from Isernia to Siena?

Book your Isernia to Siena bus tickets online with Omio and FlixBus.

Where can I stay near Siena?

There are 2290+ hotels available in Siena.

Isernia to Siena - 7 ways to travel via train, bus, car, and plane

There are 7 ways to get from Isernia to Siena by bus, train, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus
best
1. Take the bus from Isernia to Roma, Autostazione Tiburtinabus Campobasso / ...
2. Take the bus from Roma to Sienabus Bari / ...
5h 14m
€21–47
Train, bus via Rome
1. Take the train from Isernia to Roma Terminitrain Re
2. Take the train from Roma Termini to Firenze S.M.N.train Fr
3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus 131
5h 52m
€54–119
Drive 388.1 km
1. Drive from Isernia to Sienacar 388.1 km
3h 57m
€61–88
Train to Fiumicino International Airport, fly, bus
1. Take the train from Isernia to Roma Terminitrain
2. Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane FCO - FLR
3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus
7h 2m
€88–243
Train, bus
1. Take the train from Isernia to Cassinotrain Re
2. Take the bus from Cassino to Siena, Stazione FSbus
5h 16m
€29–45
Train (Trenitalia)
1. Take the train from Isernia to Roma Terminitrain Re
2. Take the train from Roma Termini to Chiusi-Chianciano T.train
3. Take the train from Chiusi-Chianciano T. to Sienatrain Re
7h 36m
€49–91
Train to Naples Airport, fly, bus
1. Take the train from Isernia to Casertatrain
2. Fly from Naples Airport (NAP) to Florence Peretola Airport (FLR)plane NAP - FLR
3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus
8h 38m
€108–270

Isernia to Siena by bus

28Weekly Buses

5h 14mAverage Duration

€21Cheapest Price

See schedules

Questions & Answers

Map of how to get from Isernia to Siena.

Launch map view

Distance: 404.1 km
Duration: 5h 14m

What companies run services between Isernia, Italy and Siena, Italy?

You can take a bus from Isernia to Siena via Roma in around 5h 14m. Alternatively, you can take a train from Isernia to Siena via Roma Termini and Chiusi-Chianciano T. in around 7h 36m.

Airlines

Train operators

Bus operators

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