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How to get fromIsernia to Sicilyby train, plane, car, car ferry, bus or train (Trenitalia)

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There are 9 ways to get from Isernia to Sicily by train, plane, car, car ferry, bus, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Naples Airport, fly to Catania–Fontanarossa Airport

    best
    1. Take the train from Isernia to Napoli Centraletrain train
    2. Fly from Naples Airport (NAP) to Catania–Fontanarossa Airport (CTA)plane plane NAP - CTA
    4h 47m
    €38–163
  2. Bus

    cheapest
    1. Take the bus from Isernia to Napoli, Autostazione Metroparkbus bus 6
    2. Take the bus from Napoli, Autostazione Metropark to Palermo Terminal Busbus bus Itabus
    13h 57m
    €31–47
  3. Drive, car ferry

    1. Drive from Isernia to Port of Naplescar car
    2. Take the car ferry from Port of Naples to Port of Palermocarferry car ferry
    10h 8m
    €58–95
  4. Bus via Caserta

    1. Take the bus from Isernia to Caserta Terminal Busbus bus 433
    2. Take the bus from Caserta Viale Vittorio Veneto to Palermo Via Tommaso Fazellobus bus Autoservizi Salemi S201
    12h 37m
    €36–62
  5. Train (Trenitalia)

    1. Take the train from Isernia to Cassinotrain train Re
    2. Take the train from Cassino to Palermo Centraletrain train Ic
    13h 25m
    €73–98
  6. Train to Naples Airport, fly to Palermo Airport

    1. Take the train from Isernia to Napoli Centraletrain train
    2. Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane plane NAP - PMO
    5h 17m
    €39–155
  7. Train to Fiumicino International Airport, fly to Catania–Fontanarossa Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)plane plane FCO - CTA
    5h 40m
    €52–192
  8. Train to Fiumicino International Airport, fly to Vincenzo Magliocco Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Vincenzo Magliocco Airport (CIY)plane plane FCO - CIY
    5h 37m
    €84–230
  9. Train to Fiumicino International Airport, fly to Palermo Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Palermo Airport (PMO)plane plane FCO - PMO
    6h 15m
    €54–214

Isernia to Sicily by bus

Calendar7Weekly Buses
Duration12h 37mAverage Duration
Ticket€36Cheapest Price
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Questions & Answers

What companies run services between Isernia, Italy and Sicily, Italy?

You can take a bus from Isernia to Piazza Boiardo via Caserta Terminal Bus, Caserta Viale Vittorio Veneto, Palermo Via Tommaso Fazello, and Stazione Centrale Pensilina Esterna in around 12h 37m. Alternatively, you can take a train from Isernia to Piazza Boiardo via Cassino, Palermo Centrale, and Stazione Centrale Pensilina Esterna in around 13h 25m.

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