What is the cheapest way to get from Isernia to Sicily?

The cheapest way to get from Isernia to Sicily is to bus which costs €25 - €40 and takes 13h 54m.

What is the fastest way to get from Isernia to Sicily?

The fastest way to get from Isernia to Sicily is to train and fly which takes 4h 39m and costs €35 - €180.

Is there a direct bus between Isernia and Sicily?

No, there is no direct bus from Isernia to Sicily. However, there are services departing from Isernia and arriving at Piazza Boiardo via Caserta Viale Vittorio Veneto and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 12h 34m.

Is there a direct train between Isernia and Sicily?

No, there is no direct train from Isernia to Sicily. However, there are services departing from Isernia and arriving at Palermo Notarbartolo via Cassino and Palermo Centrale. The journey, including transfers, takes approximately 12h 48m.

How far is it from Isernia to Sicily?

The distance between Isernia and Sicily is 519 km.

How do I travel from Isernia to Sicily without a car?

The best way to get from Isernia to Sicily without a car is to bus via Caserta which takes 12h 34m and costs €30 - €55.

How long does it take to get from Isernia to Sicily?

It takes approximately 4h 39m to get from Isernia to Sicily, including transfers.

Where do I catch the Isernia to Sicily bus from?

Isernia to Sicily bus services, operated by FlixBus, depart from Isernia station.

Where do I catch the Isernia to Sicily train from?

Isernia to Sicily train services, operated by Trenitalia S.p.A., depart from Isernia station.

Train or bus from Isernia to Sicily?

The best way to get from Isernia to Sicily is to bus via Caserta which takes 12h 34m and costs €30 - €55. Alternatively, you can train, which costs €50 - €75 and takes 12h 48m.

Where does the Isernia to Sicily bus arrive?

Isernia to Sicily bus services, operated by FlixBus, arrive at Caserta Terminal Bus station.

Where does the Isernia to Sicily train arrive?

Isernia to Sicily train services, operated by Trenitalia S.p.A., arrive at Cassino station.

How do I get a train ticket from Isernia to Sicily?

Book your Isernia to Sicily train tickets online with Omio.

Where can I stay near Sicily?

There are 263+ hotels available in Sicily.

Isernia to Sicily - 9 ways to travel via train, plane, car, ferry, and bus

There are 9 ways to get from Isernia to Sicily by train, plane, car, ferry, bus, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train to Naples Airport, fly to Catania–Fontanarossa Airport
best
1. Take the train from Isernia to Napoli Centrale
2. Fly from Naples Airport (NAP) to Catania–Fontanarossa Airport (CTA)NAP - CTA
4h 39m
€39–172
Bus
cheapest
1. Take the bus from Isernia to Napoli, Autostazione Metropark6
2. Take the bus from Napoli, Autostazione Metropark to Palermo Terminal BusItabus
13h 54m
€26–39
Drive, ferry
1. Drive from Isernia to Port of Naples
2. Take the ferry from Port of Naples to Port of Palermo
10h 7m
€58–81
Bus via Caserta
1. Take the bus from Isernia to Caserta Terminal Bus433
2. Take the bus from Caserta Viale Vittorio Veneto to Palermo Via Tommaso FazelloAutoservizi Salemi S201
12h 34m
€33–52
Train
1. Take the train from Isernia to CassinoRe
2. Take the train from Cassino to Palermo CentraleIc
12h 48m
€51–73
Train to Naples Airport, fly to Palermo Airport
1. Take the train from Isernia to Napoli Centrale
2. Fly from Naples Airport (NAP) to Palermo Airport (PMO)NAP - PMO
5h 7m
€41–164
Train to Fiumicino International Airport, fly to Catania–Fontanarossa Airport
1. Take the train from Isernia to Roma Termini
2. Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)FCO - CTA
5h 42m
€74–242
Train to Fiumicino International Airport, fly to Vincenzo Magliocco Airport
1. Take the train from Isernia to Roma Termini
2. Fly from Fiumicino International Airport (FCO) to Vincenzo Magliocco Airport (CIY)FCO - CIY
5h 34m
€99–350
Train to Fiumicino International Airport, fly to Palermo Airport
1. Take the train from Isernia to Roma Termini
2. Fly from Fiumicino International Airport (FCO) to Palermo Airport (PMO)FCO - PMO
6h 9m
€75–244

Isernia to Sicily by bus

7Weekly Buses

12h 34mAverage Duration

€33Cheapest Price

See schedules

Questions & Answers

Launch map view

Distance: 519 km
Duration: 4h 39m

What companies run services between Isernia, Italy and Sicily, Italy?

You can take a bus from Isernia to Piazza Boiardo via Caserta Terminal Bus, Caserta Viale Vittorio Veneto, Palermo Via Tommaso Fazello, and Stazione Centrale Pensilina Esterna in around 12h 34m. Alternatively, you can take a train from Isernia to Palermo Notarbartolo via Cassino and Palermo Centrale in around 12h 48m.

Transport is disrupted due to the Russia-Ukraine war. Read more

Airlines

Train operators

Bus operators

Ferry operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.