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How to get fromIsernia to Messinaby train, ferry, bus, car, or plane

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There are 9 ways to get from Isernia to Messina by train, ferry, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, ferry

    best
    1. Take the train from Isernia to Napoli Afragolatrain train Re
    2. Take the train from Napoli Afragola to Villa S.Giovannitrain train Fr
    3. Take the ferry from Villa S.Giovanni to Messina Marittimaferry ferry V1 / ...
    7h 11m

  2. Bus via Caserta

    cheapest
    1. Take the bus from Isernia to Caserta Terminal Busbus bus 433
    2. Take the bus from Caserta pzza Garibaldi to Messina Centrale Stationbus bus Autoservizi Salemi S201
    8h 55m
    €28–61

  3. Drive, ferry

    1. Drive from Isernia to Villa San Giovannicar car
    2. Take the ferry from Villa San Giovanni to Messina Marittimaferry ferry
    6h 13m
    €105–152

  4. Train to Fiumicino International Airport, fly to Reggio Calabria Airport, ferry

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Reggio Calabria Airport (REG)plane plane FCO - REG
    3. Take the ferry from Villa S.Giovanni to Messina Marittimaferry ferry
    7h 6m

  5. Bus

    1. Take the bus from Isernia to Salernobus bus 433
    2. Take the bus from Salerno to Messinabus bus N528 / ...
    11h 25m
    €50–82

  6. Train to Fiumicino International Airport, fly to Catania–Fontanarossa Airport, train

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)plane plane FCO - CTA
    3. Take the train from Catania Centrale to Messina Centraletrain train
    8h 3m
    €58–155

  7. Train to Naples Airport, fly to Catania–Fontanarossa Airport, train

    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Catania–Fontanarossa Airport (CTA)plane plane NAP - CTA
    3. Take the train from Catania Centrale to Messina Centraletrain train
    7h 34m
    €47–198

  8. Train to Fiumicino International Airport, fly to Palermo Airport, train

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Palermo Airport (PMO)plane plane FCO - PMO
    3. Take the train from Palermo Centrale to Messina Centraletrain train
    9h 42m
    €72–208

  9. Bus, bus to Abruzzo Airport, fly to Catania–Fontanarossa Airport, train

    1. Take the bus from Isernia to San Salvo Marinabus bus
    2. Take the bus from San Salvo Marina to Pescara Airportbus bus
    3. Fly from Abruzzo Airport (PSR) to Catania–Fontanarossa Airport (CTA)plane plane PSR - CTA
    4. Take the train from Catania Centrale to Messina Centraletrain train
    8h 52m
    €54–220

Fiumicino International Airport (FCO) to Reggio Calabria Airport (REG) flights

Calendar14Weekly Planes
Duration1h 10mAverage Duration
Ticket€61Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Isernia to Messina.ExpandLaunch map view
  • Distance: 547.3 km
  • Duration: 7h 11m

What companies run services between Isernia, Italy and Messina, Italy?

You can take a bus from Isernia to Messina Centrale Station via Caserta Terminal Bus and Caserta pzza Garibaldi in around 8h 55m.

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