There are 10 ways to get from Isernia to Messina by train, ferry, bus, car ferry, car, train (Trenitalia), or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, ferry
best- Take the train from Isernia to Napoli Centraletrain Re
- Take the train from Napoli Centrale to Villa San Giovannitrain
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
8h 8mBus
cheapest- Take the bus from Isernia to Napoli P.zza Garibaldibus 433
- Take the bus from Napoli P.zza Garibaldi to Messinabus N590 / ...
9h 45m€37–67Bus, car ferry
- Take the bus from Isernia to Salernobus 433
- Take the car ferry from Port of Salerno to Messinacarferry
14h 8m€41–81Drive, ferry
- Drive from Isernia to Villa San Giovannicar
- Take the ferry from Villa San Giovanni to Messina Marittimaferry
6h 13m€92–132Train (Trenitalia)
- Take the train from Isernia to Casertatrain Re
- Take the train from Caserta to Messina Centraletrain Ic
8h 48m€57–129Train to Naples Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Isernia to Casertatrain
- Fly from Naples Airport (NAP) to Catania–Fontanarossa Airport (CTA)plane NAP - CTA
- Take the train from Catania Centrale to Messina Centraletrain
7h 56m€46–157Train to Fiumicino International Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)plane FCO - CTA
- Take the train from Catania Centrale to Messina Centraletrain
8h 33m€68–210Train to Fiumicino International Airport, fly to Reggio Calabria Airport, ferry
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Reggio Calabria Airport (REG)plane FCO - REG
- Take the ferry from Reggio Calabria to Messina Marittimaferry
7h 57m€78–202Train to Naples Airport, fly to Palermo Airport, train
- Take the train from Isernia to Casertatrain
- Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane NAP - PMO
- Take the train from Palermo Centrale to Messina Centraletrain
9h 37m€61–191Bus, train to Abruzzo Airport, fly to Catania–Fontanarossa Airport, train
- Take the bus from Isernia to Montenero Bivio SS16bus
- Take the train from Montenero-Petacciato to Pescara Porta Nuovatrain
- Fly from Abruzzo Airport (PSR) to Catania–Fontanarossa Airport (CTA)plane PSR - CTA
- Take the train from Catania Centrale to Messina Centraletrain
9h 47m€70–239
Isernia to Messina by bus
Questions & Answers
The cheapest way to get from Isernia to Messina is to bus which costs €35 - €70 and takes 9h 45m.
The fastest way to get from Isernia to Messina is to drive and ferry which takes 6h 13m and costs €90 - €140.
No, there is no direct bus from Isernia to Messina. However, there are services departing from Isernia and arriving at Messina via Napoli P.zza Garibaldi. The journey, including transfers, takes approximately 9h 45m.
No, there is no direct train from Isernia to Messina. However, there are services departing from Isernia and arriving at Messina Centrale via Caserta. The journey, including transfers, takes approximately 8h 48m.
The distance between Isernia and Messina is 575 km.
The best way to get from Isernia to Messina without a car is to train and ferry which takes 8h 8m and costs .
It takes approximately 8h 8m to get from Isernia to Messina, including transfers.
Isernia to Messina bus services, operated by FlixBus, depart from Isernia station.
Isernia to Messina train services, operated by Trenitalia, depart from Isernia station.
The best way to get from Isernia to Messina is to bus which takes 9h 45m and costs €35 - €70. Alternatively, you can train, which costs €55 - €130 and takes 8h 48m.
What companies run services between Isernia, Italy and Messina, Italy?
You can take a bus from Isernia to Messina via Napoli P.zza Garibaldi in around 9h 45m. Alternatively, you can take a train from Isernia to Messina Centrale via Caserta in around 8h 48m.
- Website
- ryanair.com
Flights from Naples Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- €23–120
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- €25–120
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 10m
- When
- Wednesday
- Estimated price
- €25–120
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €30–110
Flights from Abruzzo Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- €45–190
- Website
- easyjet.com
Flights from Naples Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €21–100
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- €21–100
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €35–140
Flights from Fiumicino International Airport to Reggio Calabria Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €40–150
- Website
- aeroitalia.com
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €30–130
- Website
- flexflight.dk
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €30–130
- Website
- neosair.it
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 10m
- When
- Saturday
- Estimated price
- €130–410
Flights from Abruzzo Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 25m
- When
- Thursday
- Estimated price
- €150–480
- Website
- volotea.com
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €21–100
- Website
- tuifly.be
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Friday
- Estimated price
- €70–260
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Isernia to Napoli Centrale
- Ave. Duration
- 2h 5m
- Frequency
- 4 times a day
- Estimated price
- €15–27
- Website
- https://www.trenitalia.com/en.html
Train from Isernia to Caserta
- Ave. Duration
- 1h 18m
- Frequency
- 4 times a day
- Estimated price
- €11–20
- Website
- https://www.trenitalia.com/en.html
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €11–20
- Website
- https://www.trenitalia.com/en.html
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a day
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- €28–50
- Website
- https://www.trenitalia.com/en.html
Train from Montenero-Petacciato to Pescara Porta Nuova
- Ave. Duration
- 1h
- Frequency
- Every 3 hours
- Estimated price
- €9–16
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Napoli Centrale to Villa San Giovanni
- Ave. Duration
- 3h 58m
- Frequency
- Once daily
- Estimated price
- €55–120
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Caserta to Messina Centrale
- Ave. Duration
- 6h 30m
- Frequency
- 4 times a week
- Estimated price
- €45–110
- Website
- https://www.trenitalia.com/en.html
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 1h 27m
- Frequency
- Twice daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- €22–50
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Isernia to Napoli P.zza Garibaldi
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- €7–13
- Website
- https://www.flixbus.co.uk
Bus from Napoli P.zza Garibaldi to Messina
- Ave. Duration
- 6h 45m
- Frequency
- Twice daily
- Estimated price
- €30–55
- Website
- https://www.flixbus.co.uk
Bus from Isernia to Salerno
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- €10–19
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Isernia to Montenero Bivio SS16
- Ave. Duration
- 1h 22m
- Frequency
- Once daily
- Estimated price
- €5–7
- Schedules at
- atm-molise.it
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.090.57.37
- servizioclienti@carontetourist.it
- Website
- carontetourist.it
Car ferry from Port of Salerno to Messina
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- €29–60
- Schedules at
- carontetourist.it
- Passenger
- €29
- Cars
- €60
- Phone
- 3409848540
- info@blujetlines.it
- Website
- blujetlines.it
Ferry from Villa San Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
Ferry from Reggio Calabria to Messina Marittima
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €3–4
- Schedules at
- blujetlines.it
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More Questions & Answers
Isernia to Messina bus services, operated by FlixBus, arrive at Napoli P.zza Garibaldi station.
Isernia to Messina train services, operated by Trenitalia, arrive at Caserta station.
Book your Isernia to Messina train tickets online with Omio.
Book your Isernia to Messina bus tickets online with Omio and FlixBus.
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