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How to get fromIsernia to Messinaby train, ferry, bus, car, plane or train (Trenitalia)

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There are 9 ways to get from Isernia to Messina by train, ferry, bus, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, ferry

    best
    1. Take the train from Isernia to Napoli Centraletrain train Re
    2. Take the train from Napoli Centrale to Villa San Giovannitrain train
    3. Take the ferry from Villa S.Giovanni to Messina Marittimaferry ferry V1 / ...
    8h 8m
  2. Bus

    cheapest
    1. Take the bus from Isernia to Caserta Terminal Busbus bus 433
    2. Take the bus from Caserta Terminal Bus to Messina Main Train Stationbus bus Itabus
    10h 9m
    €23–40
  3. Bus via Caserta

    1. Take the bus from Isernia to Caserta Terminal Busbus bus 433
    2. Take the bus from Caserta Viale Vittorio Veneto to Messina Piazza della Repubblicabus bus Autoservizi Salemi S201
    8h 55m
    €24–41
  4. Drive, ferry

    1. Drive from Isernia to Villa San Giovannicar car
    2. Take the ferry from Villa San Giovanni to Messina Marittimaferry ferry
    6h 13m
    €91–131
  5. Train to Naples Airport, fly to Catania–Fontanarossa Airport, train

    1. Take the train from Isernia to Napoli Centraletrain train
    2. Fly from Naples Airport (NAP) to Catania–Fontanarossa Airport (CTA)plane plane NAP - CTA
    3. Take the train from Catania Centrale to Messina Centraletrain train
    7h 28m
    €46–170
  6. Train

    1. Take the train from Isernia to Napoli Centraletrain train Re
    2. Take the train from Napoli Centrale to Messina Centraletrain train Ic
    8h 55m
    €36–92
  7. Train to Fiumicino International Airport, fly to Catania–Fontanarossa Airport, train

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)plane plane FCO - CTA
    3. Take the train from Catania Centrale to Messina Centraletrain train
    8h 26m
    €58–196
  8. Train to Fiumicino International Airport, fly to Reggio Calabria Airport, ferry

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Reggio Calabria Airport (REG)plane plane FCO - REG
    3. Take the ferry from Reggio Calabria to Messina Marittimaferry ferry
    7h 57m
    €65–209
  9. Train to Naples Airport, fly to Palermo Airport, train

    1. Take the train from Isernia to Napoli Centraletrain train
    2. Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane plane NAP - PMO
    3. Take the train from Palermo Centrale to Messina Centraletrain train
    9h 20m
    €54–169

Isernia to Messina by bus

Calendar7Weekly Buses
Duration8h 55mAverage Duration
Ticket€24Cheapest Price
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Questions & Answers

What companies run services between Isernia, Italy and Messina, Italy?

You can take a bus from Isernia to Messina Piazza della Repubblica via Caserta Terminal Bus and Caserta Viale Vittorio Veneto in around 8h 55m. Alternatively, you can take a train from Isernia to Messina Centrale via Napoli Centrale in around 8h 55m.

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