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How to get fromIsernia to Messinaby train, ferry, bus, car ferry, car, train (Trenitalia) or plane

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There are 10 ways to get from Isernia to Messina by train, ferry, bus, car ferry, car, train (Trenitalia), or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, ferry

    best
    1. Take the train from Isernia to Napoli Centraletrain train Re
    2. Take the train from Napoli Centrale to Villa San Giovannitrain train
    3. Take the ferry from Villa S.Giovanni to Messina Marittimaferry ferry V1 / ...
    8h 8m
  2. Bus

    cheapest
    1. Take the bus from Isernia to Napoli P.zza Garibaldibus bus 433
    2. Take the bus from Napoli P.zza Garibaldi to Messinabus bus N590 / ...
    9h 45m
    €37–67
  3. Bus, car ferry

    1. Take the bus from Isernia to Salernobus bus 433
    2. Take the car ferry from Port of Salerno to Messinacarferry car ferry
    14h 8m
    €41–81
  4. Drive, ferry

    1. Drive from Isernia to Villa San Giovannicar car
    2. Take the ferry from Villa San Giovanni to Messina Marittimaferry ferry
    6h 13m
    €92–132
  5. Train (Trenitalia)

    1. Take the train from Isernia to Casertatrain train Re
    2. Take the train from Caserta to Messina Centraletrain train Ic
    8h 48m
    €57–129
  6. Train to Naples Airport, fly to Catania–Fontanarossa Airport, train

    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Catania–Fontanarossa Airport (CTA)plane plane NAP - CTA
    3. Take the train from Catania Centrale to Messina Centraletrain train
    7h 56m
    €46–157
  7. Train to Fiumicino International Airport, fly to Catania–Fontanarossa Airport, train

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)plane plane FCO - CTA
    3. Take the train from Catania Centrale to Messina Centraletrain train
    8h 33m
    €68–210
  8. Train to Fiumicino International Airport, fly to Reggio Calabria Airport, ferry

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Reggio Calabria Airport (REG)plane plane FCO - REG
    3. Take the ferry from Reggio Calabria to Messina Marittimaferry ferry
    7h 57m
    €78–202
  9. Train to Naples Airport, fly to Palermo Airport, train

    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane plane NAP - PMO
    3. Take the train from Palermo Centrale to Messina Centraletrain train
    9h 37m
    €61–191
  10. Bus, train to Abruzzo Airport, fly to Catania–Fontanarossa Airport, train

    1. Take the bus from Isernia to Montenero Bivio SS16bus bus
    2. Take the train from Montenero-Petacciato to Pescara Porta Nuovatrain train
    3. Fly from Abruzzo Airport (PSR) to Catania–Fontanarossa Airport (CTA)plane plane PSR - CTA
    4. Take the train from Catania Centrale to Messina Centraletrain train
    9h 47m
    €70–239

Isernia to Messina by bus

Calendar10Weekly Buses
Duration9h 45mAverage Duration
Ticket€37Cheapest Price
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Questions & Answers

What companies run services between Isernia, Italy and Messina, Italy?

You can take a bus from Isernia to Messina via Napoli P.zza Garibaldi in around 9h 45m. Alternatively, you can take a train from Isernia to Messina Centrale via Caserta in around 8h 48m.

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