There are 9 ways to get from Isernia to Messina by train, ferry, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, ferry
best- Take the train from Isernia to Napoli Centraletrain Re
- Take the train from Napoli Centrale to Villa San Giovannitrain
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
8h 8mBus
cheapest- Take the bus from Isernia to Caserta Terminal Busbus 433
- Take the bus from Caserta Terminal Bus to Messina Main Train Stationbus Itabus
10h 9m€23–40Bus via Caserta
- Take the bus from Isernia to Caserta Terminal Busbus 433
- Take the bus from Caserta Viale Vittorio Veneto to Messina Piazza della Repubblicabus Autoservizi Salemi S201
8h 55m€24–41Drive, ferry
- Drive from Isernia to Villa San Giovannicar
- Take the ferry from Villa San Giovanni to Messina Marittimaferry
6h 13m€91–131Train to Naples Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Isernia to Napoli Centraletrain
- Fly from Naples Airport (NAP) to Catania–Fontanarossa Airport (CTA)plane NAP - CTA
- Take the train from Catania Centrale to Messina Centraletrain
7h 28m€46–170Train
- Take the train from Isernia to Napoli Centraletrain Re
- Take the train from Napoli Centrale to Messina Centraletrain Ic
8h 55m€36–92Train to Fiumicino International Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)plane FCO - CTA
- Take the train from Catania Centrale to Messina Centraletrain
8h 26m€58–196Train to Fiumicino International Airport, fly to Reggio Calabria Airport, ferry
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Reggio Calabria Airport (REG)plane FCO - REG
- Take the ferry from Reggio Calabria to Messina Marittimaferry
7h 57m€65–209Train to Naples Airport, fly to Palermo Airport, train
- Take the train from Isernia to Napoli Centraletrain
- Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane NAP - PMO
- Take the train from Palermo Centrale to Messina Centraletrain
9h 20m€54–169
Isernia to Messina by bus
Questions & Answers
The cheapest way to get from Isernia to Messina is to bus which costs €23 - €45 and takes 10h 9m.
The fastest way to get from Isernia to Messina is to drive and ferry which takes 6h 13m and costs €90 - €140.
No, there is no direct bus from Isernia to Messina. However, there are services departing from Isernia and arriving at Messina Piazza della Repubblica via Caserta Viale Vittorio Veneto. The journey, including transfers, takes approximately 8h 55m.
No, there is no direct train from Isernia to Messina. However, there are services departing from Isernia and arriving at Messina Centrale via Napoli Centrale. The journey, including transfers, takes approximately 8h 55m.
The distance between Isernia and Messina is 575 km.
The best way to get from Isernia to Messina without a car is to train and ferry which takes 8h 8m and costs .
It takes approximately 8h 8m to get from Isernia to Messina, including transfers.
Isernia to Messina bus services, operated by FlixBus, depart from Isernia station.
Isernia to Messina train services, operated by Trenitalia S.p.A., depart from Isernia station.
The best way to get from Isernia to Messina is to bus via Caserta which takes 8h 55m and costs €24 - €45. Alternatively, you can train, which costs €35 - €95 and takes 8h 55m.
What companies run services between Isernia, Italy and Messina, Italy?
You can take a bus from Isernia to Messina Piazza della Repubblica via Caserta Terminal Bus and Caserta Viale Vittorio Veneto in around 8h 55m. Alternatively, you can take a train from Isernia to Messina Centrale via Napoli Centrale in around 8h 55m.
- Website
- ryanair.com
Flights from Naples Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 10m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €35–150
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €29–140
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 15m
- When
- Friday
- Estimated price
- €29–140
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €27–140
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €40–130
Flights from Fiumicino International Airport to Reggio Calabria Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €40–180
- Website
- aeroitalia.com
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €30–270
- Website
- flexflight.dk
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €30–270
- Website
- easyjet.com
Flights from Naples Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €23–110
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 55 min
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €22–120
- Website
- volotea.com
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h
- When
- Thursday
- Estimated price
- €22–95
- Website
- tuifly.be
Flights from Naples Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Friday
- Estimated price
- €85–280
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Isernia to Napoli Centrale
- Ave. Duration
- 2h 5m
- Frequency
- 4 times a day
- Estimated price
- €8–13
- Website
- https://www.trenitalia.com/en.html
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a day
- Estimated price
- €11–17
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 44m
- Frequency
- Every 4 hours
- Estimated price
- €13–20
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Napoli Centrale to Villa San Giovanni
- Ave. Duration
- 3h 58m
- Frequency
- Once daily
- Estimated price
- €29–85
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 1h 13m
- Frequency
- Twice daily
- Estimated price
- €12
- Website
- https://www.trenitalia.com/en.html
Train from Napoli Centrale to Messina Centrale
- Ave. Duration
- 5h 50m
- Frequency
- Twice daily
- Estimated price
- €27–80
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- €14–26
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Isernia to Caserta Terminal Bus
- Ave. Duration
- 1h 15m
- Frequency
- Twice daily
- Estimated price
- €7–18
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Caserta Viale Vittorio Veneto to Messina Piazza della Repubblica
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- €17–24
- Schedules at
- autoservizisalemi.it
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Caserta Terminal Bus to Messina Main Train Station
- Ave. Duration
- 7h 54m
- Frequency
- Once daily
- Estimated price
- €16–23
- Website
- https://www.itabus.it/en/home
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- 342 32 55 869
- Website
- blujetlines.it
Ferry from Villa San Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
Ferry from Reggio Calabria to Messina Marittima
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €3–4
- Schedules at
- blujetlines.it
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More Questions & Answers
Isernia to Messina bus services, operated by FlixBus, arrive at Caserta Terminal Bus station.
Isernia to Messina train services, operated by Trenitalia S.p.A., arrive at Napoli Centrale station.
Book your Isernia to Messina bus tickets online with Omio.
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