There are 11 ways to get from Isernia to Lugano by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Milano Centraletrain
- Take the train from Milano Centrale to Luganotrain Ec
7h 37mCHF 102–198Train to Naples Airport, fly to Milano Malpensa Airport, train
cheapest- Take the train from Isernia to Casertatrain
- Fly from Naples Airport (NAP) to Milano Malpensa Airport (MXP)plane NAP - MXP
- Take the train from Malpensa Aeroporto T1 to Luganotrain
7h 22mCHF 32–165Bus
- Take the bus from Isernia to Casello - A1 Ingresso Caianellobus 6
- Take the bus from Caianello to Luganobus
13h 13mCHF 57–87Drive 788.6 km
- Drive from Isernia to Luganocar 788.6 km
8h 2mCHF 132–190Train via Isernia
- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Milano Centraletrain Fr / ...
- Take the train from Milano Centrale to Luganotrain Ec
8h 10mCHF 102–218Bus via Bologna
- Take the bus from Isernia to Bologna Centralebus 433
- Take the bus from Bologna to Luganobus FlixBus 421 / ...
14h 25mCHF 56–97Train to Naples Airport, fly to Milan Linate Airport, train
- Take the train from Isernia to Casertatrain
- Fly from Naples Airport (NAP) to Milan Linate Airport (LIN)plane NAP - LIN
- Take the train from Monza to Luganotrain
7h 24mCHF 68–198Train to Naples Airport, fly to Il Caravaggio International Airport, bus, train
- Take the train from Isernia to Casertatrain
- Fly from Naples Airport (NAP) to Il Caravaggio International Airport (BGY)plane NAP - BGY
- Take the bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoiabus
- Take the train from Milano Centrale to Luganotrain
7h 50mCHF 61–246Bus, bus to Abruzzo Airport, fly to Milano Malpensa Airport, train
- Take the bus from Isernia to San Salvo Marinabus
- Take the bus from San Salvo Marina to Pescara Airportbus
- Fly from Abruzzo Airport (PSR) to Milano Malpensa Airport (MXP)plane PSR - MXP
- Take the train from Malpensa Aeroporto T1 to Luganotrain
8h 20mCHF 35–187Train, train to Salerno Costa D'Amalfi Airport, fly to Milano Malpensa Airport
- Take the train from Isernia to Casertatrain
- Take the train from Caserta to Salernotrain
- Fly from Salerno Costa D'Amalfi Airport (QSR) to Milano Malpensa Airport (MXP)plane QSR - MXP
- Take the train from Malpensa Aeroporto T1 to Luganotrain
9h 7mCHF 51–191Bus, bus to Abruzzo Airport, fly to Il Caravaggio International Airport, train
- Take the bus from Isernia to San Salvo Marinabus
- Take the bus from San Salvo Marina to Pescara Airportbus
- Fly from Abruzzo Airport (PSR) to Il Caravaggio International Airport (BGY)plane PSR - BGY
- Take the bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoiabus
- Take the train from Milano Centrale to Luganotrain
8h 47mCHF 51–258
Isernia to Lugano by bus and foot
Comparing Your Travel Options
The cheapest way to get from Isernia to Lugano is to bus and fly and train which costs SFr 35 - SFr 190 and takes 8h 20m.
The fastest way to get from Isernia to Lugano is to train and fly which takes 7h 22m and costs SFr 30 - SFr 170.
No, there is no direct bus from Isernia to Lugano. However, there are services departing from Isernia and arriving at Lugano via Caianello. The journey, including transfers, takes approximately 13h 13m.
No, there is no direct train from Isernia to Lugano. However, there are services departing from Isernia and arriving at Lugano via Roma Termini and Milano Centrale. The journey, including transfers, takes approximately 7h 37m.
The distance between Isernia and Lugano is 839 km. The road distance is 788.6 km.
The best way to get from Isernia to Lugano without a car is to train which takes 7h 37m and costs SFr 100 - SFr 200.
It takes approximately 7h 37m to get from Isernia to Lugano, including transfers.
Isernia to Lugano bus services, operated by Società Autocooperative Trasporti Italiani S.p.A., depart from Isernia station.
Isernia to Lugano train services, operated by Trenitalia, depart from Isernia station.
The best way to get from Isernia to Lugano is to train which takes 7h 37m and costs SFr 100 - SFr 200. Alternatively, you can bus, which costs SFr 55 - SFr 90 and takes 13h 13m.
What companies run services between Isernia, Italy and Lugano, Switzerland?
You can take a train from Isernia to Lugano via Roma Termini and Milano Centrale in around 7h 37m. Alternatively, you can take a bus from Isernia to Lugano via Casello - A1 Ingresso Caianello and Caianello in around 13h 13m.
- Website
- ryanair.com
Flights from Naples Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- CHF 25–150
Flights from Naples Airport to Il Caravaggio International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- CHF 40–190
Flights from Abruzzo Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- CHF 22–170
Flights from Abruzzo Airport to Il Caravaggio International Airport
- Ave. Duration
- 1h 14m
- When
- Tuesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 35–210
- Website
- easyjet.com
Flights from Naples Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- CHF 23–150
Flights from Salerno Costa D'Amalfi Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 35m
- When
- Sunday
- Estimated price
- CHF 50–260
- Website
- ita-airways.com
Flights from Naples Airport to Milan Linate Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- CHF 50–150
Flights from Naples Airport to Milan Linate Airport via Rome
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- CHF 50–150
- Website
- flyulendo.com
Flights from Naples Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- CHF 12–130
- Website
- aeroitalia.com
Flights from Salerno Costa D'Amalfi Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- CHF 30–150
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- CHF 20–29
- Website
- Trenitalia
Train from Isernia to Caserta
- Ave. Duration
- 1h 12m
- Frequency
- Every 3 hours
- Estimated price
- CHF 10–14
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- CHF 20–29
- Website
- Trenitalia
Train from Isernia to Caserta
- Ave. Duration
- 1h 12m
- Frequency
- Every 3 hours
- Estimated price
- CHF 10–14
- Website
- Trenitalia
Train from Isernia to Caserta
- Ave. Duration
- 1h 12m
- Frequency
- Every 3 hours
- Estimated price
- CHF 10–14
- Website
- Trenitalia
Train from Isernia to Caserta
- Ave. Duration
- 1h 12m
- Frequency
- Every 3 hours
- Estimated price
- CHF 10–14
- Website
- Trenitalia
Train from Caserta to Salerno
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- CHF 6–10
- Website
- Trenitalia
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- CHF 60–110
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 4h 17m
- Frequency
- 4 times a day
- Estimated price
- CHF 60–100
- Website
- Italo Treno
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- Trenitalia Eurocity
Train from Milano Centrale to Lugano
- Ave. Duration
- 1h 18m
- Frequency
- Hourly
- Estimated price
- CHF 21–60
- Website
- Trenitalia Eurocity
- 1st Class
- CHF 40–60
- 2nd Class
- CHF 21–29
Train from Milano Centrale to Lugano
- Ave. Duration
- 1h 18m
- Frequency
- Hourly
- Estimated price
- CHF 21–60
- Website
- Trenitalia Eurocity
- 1st Class
- CHF 40–60
- 2nd Class
- CHF 21–29
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Lugano
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- Trenord
Train from Monza to Lugano
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- CHF 3–5
- Website
- Trenord
Train from Milano Centrale to Lugano
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Lugano
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Lugano
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- Trenord
Train from Milano Centrale to Lugano
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- Trenord
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 39m
- Frequency
- Every 30 minutes
- Estimated price
- CHF 70–130
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Caserta to Salerno
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Estimated price
- CHF 6–12
- Website
- Trenitalia Intercity
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Isernia to Casello - A1 Ingresso Caianello
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- CHF 2–3
- Schedules at
- satiautobus.com
Bus from San Salvo Marina to Pescara Airport
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- CHF 3–5
- Schedules at
- satiautobus.com
Bus from San Salvo Marina to Pescara Airport
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- CHF 3–5
- Schedules at
- satiautobus.com
- Phone
- +39 0827 34 117
- info@gruppodimaio.it
- Website
- gruppodimaio.it
Bus from Caianello to Lugano
- Ave. Duration
- 11h 5m
- Frequency
- Twice a week
- Estimated price
- CHF 55–85
- Schedules at
- gruppodimaio.it
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Isernia to Bologna Centrale
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- CHF 40–65
- Website
- Flixbus
Bus from Bologna to Lugano
- Ave. Duration
- 5h
- Frequency
- 4 times a day
- Estimated price
- CHF 23–35
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Bologna to Lugano
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- CHF 14–25
- Website
- Itabus S.p.A.
- customerservices@terravision.eu
- Website
- TERRAVISION
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 4–21
- Website
- TERRAVISION
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 4–21
- Website
- TERRAVISION
- Phone
- 035.319366
- ticket@orioshuttle.com
- Website
- orioshuttle.com
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 10–13
- Schedules at
- orioshuttle.com
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 10–13
- Schedules at
- orioshuttle.com
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Isernia to San Salvo Marina
- Ave. Duration
- 1h 17m
- Frequency
- Once a week
- Estimated price
- CHF 3–6
- Schedules at
- atm-molise.it
Bus from Isernia to San Salvo Marina
- Ave. Duration
- 1h 17m
- Frequency
- Once a week
- Estimated price
- CHF 3–6
- Schedules at
- atm-molise.it
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Booking & Getting There
Isernia to Lugano bus services, operated by Società Autocooperative Trasporti Italiani S.p.A., arrive at Casello - A1 Ingresso Caianello station.
Isernia to Lugano train services, operated by Trenitalia, arrive at Roma Termini station.
Yes, the driving distance between Isernia to Lugano is 789 km. It takes approximately 8h 2m to drive from Isernia to Lugano.
Book your Isernia to Lugano train tickets online with Omio.
Book your Isernia to Lugano bus tickets online with Omio.
There are 6759+ hotels available in Lugano.






















































