There are 12 ways to get from Isernia to Como by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Milano Centraletrain
- Take the train from Milano Centrale to Como S. Giovannitrain
6h 58m€102–174Bus, bus to Abruzzo Airport, fly to Milano Malpensa Airport
cheapest- Take the bus from Isernia to San Salvo Marinabus
- Take the bus from San Salvo Marina to Pescara Airportbus
- Fly from Abruzzo Airport (PSR) to Milano Malpensa Airport (MXP)plane PSR - MXP
7h 30m€35–179Bus
- Take the bus from Isernia to Casello - A1 Ingresso Caianellobus 6
- Take the bus from Casello - A1 Ingresso Caianello to Comobus
8h 42m€87–122Drive 757.3 km
- Drive from Isernia to Comocar 757.3 km
7h 46m€136–197Train to Fiumicino International Airport, fly to Milan Linate Airport
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)plane FCO - LIN
7h 2m€85–214Train via Isernia
- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Milano Centraletrain Fr / ...
- Take the train from Milano Centrale to Como S. Giovannitrain
7h 45m€102–194Bus via Florence
- Take the bus from Isernia to Florence Villa Constanza Bus Stationbus 433
- Take the bus from Florence Villa Constanza Bus Station to Comobus 518
16h 45m€87–133Train to Naples Airport, fly to Milano Malpensa Airport
- Take the train from Isernia to Casertatrain
- Fly from Naples Airport (NAP) to Milano Malpensa Airport (MXP)plane NAP - MXP
6h 33m€36–177Train to Naples Airport, fly to Milan Linate Airport
- Take the train from Isernia to Casertatrain
- Fly from Naples Airport (NAP) to Milan Linate Airport (LIN)plane NAP - LIN
6h 38m€73–207Train, train to Salerno Costa D'Amalfi Airport, fly to Milan Linate Airport
- Take the train from Isernia to Casertatrain
- Take the train from Caserta to Salernotrain
- Fly from Salerno Costa D'Amalfi Airport (QSR) to Milan Linate Airport (LIN)plane QSR - LIN
9h 7m€94–334Train, train to Salerno Costa D'Amalfi Airport, fly to Milano Malpensa Airport
- Take the train from Isernia to Casertatrain
- Take the train from Caserta to Salernotrain
- Fly from Salerno Costa D'Amalfi Airport (QSR) to Milano Malpensa Airport (MXP)plane QSR - MXP
8h 52m€55–214Bus, bus to Abruzzo Airport, fly to Il Caravaggio International Airport, train
- Take the bus from Isernia to San Salvo Marinabus
- Take the bus from San Salvo Marina to Pescara Airportbus
- Fly from Abruzzo Airport (PSR) to Il Caravaggio International Airport (BGY)plane PSR - BGY
- Take the bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoiabus
- Take the train from Milano Centrale to Como S. Giovannitrain
8h 4m€67–288
Isernia to Como by train
Comparing Your Travel Options
The cheapest way to get from Isernia to Como is to bus and fly which costs €35 - €180 and takes 7h 30m.
The fastest way to get from Isernia to Como is to train and fly which takes 6h 33m and costs €35 - €180.
No, there is no direct bus from Isernia to Como. However, there are services departing from Isernia and arriving at Como via Casello - A1 Ingresso Caianello. The journey, including transfers, takes approximately 8h 42m.
No, there is no direct train from Isernia to Como. However, there are services departing from Isernia and arriving at Como S. Giovanni via Roma Termini and Milano Centrale. The journey, including transfers, takes approximately 6h 58m.
The distance between Isernia and Como is 813 km. The road distance is 757.3 km.
The best way to get from Isernia to Como without a car is to train which takes 6h 58m and costs €100 - €180.
It takes approximately 6h 58m to get from Isernia to Como, including transfers.
Isernia to Como bus services, operated by Società Autocooperative Trasporti Italiani S.p.A., depart from Isernia station.
Isernia to Como train services, operated by Trenitalia, depart from Isernia station.
The best way to get from Isernia to Como is to train which takes 6h 58m and costs €100 - €180. Alternatively, you can bus, which costs €85 - €130 and takes 8h 42m.
What companies run services between Isernia, Italy and Como, Italy?
You can take a train from Isernia to Como S. Giovanni via Roma Termini and Milano Centrale in around 6h 58m. Alternatively, you can take a bus from Isernia to Como via Casello - A1 Ingresso Caianello in around 8h 42m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Milan Linate Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €55–170
Flights from Naples Airport to Milan Linate Airport
- Ave. Duration
- 1h 20m
- When
- Monday to Saturday
- Estimated price
- €55–160
Flights from Salerno Costa D'Amalfi Airport to Milan Linate Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €90–310
- Website
- ryanair.com
Flights from Naples Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 35m
- When
- Tuesday
- Estimated price
- €23–170
Flights from Abruzzo Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €22–160
Flights from Abruzzo Airport to Il Caravaggio International Airport
- Ave. Duration
- 1h 10m
- When
- Monday, Sunday, and Friday
- Estimated price
- €40–200
- Website
- easyjet.com
Flights from Naples Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 30m
- When
- Tuesday
- Estimated price
- €30–140
Flights from Naples Airport to Milan Linate Airport via Split
- Ave. Duration
- 3h 25m
- When
- Thursday
- Estimated price
- €75–390
Flights from Salerno Costa D'Amalfi Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- €29–120
- Website
- aeroitalia.com
Flights from Fiumicino International Airport to Milan Linate Airport via Olbia
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €120–220
Flights from Salerno Costa D'Amalfi Airport to Milan Linate Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €70–290
Flights from Salerno Costa D'Amalfi Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 30m
- When
- Monday to Saturday
- Estimated price
- €35–170
- Website
- flyulendo.com
Flights from Naples Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €13–130
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- 5 times a day
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- 5 times a day
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- 5 times a day
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Isernia to Caserta
- Ave. Duration
- 1h 12m
- Frequency
- 5 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Isernia to Caserta
- Ave. Duration
- 1h 12m
- Frequency
- 5 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Isernia to Caserta
- Ave. Duration
- 1h 12m
- Frequency
- 5 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Caserta to Salerno
- Ave. Duration
- 1h 2m
- Frequency
- Every 2 hours
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Isernia to Caserta
- Ave. Duration
- 1h 12m
- Frequency
- 5 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Caserta to Salerno
- Ave. Duration
- 1h 2m
- Frequency
- Every 2 hours
- Estimated price
- €7–11
- Website
- Trenitalia
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–120
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 50m
- Frequency
- Every 4 hours
- Estimated price
- €65–110
- Website
- Italo Treno
Train from Milano Centrale to Como S. Giovanni
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- €15–24
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Milano Centrale to Como S. Giovanni
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- €15–24
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Milano Centrale to Como S. Giovanni
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- €15–24
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 39m
- Frequency
- Hourly
- Estimated price
- €75–140
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Caserta to Salerno
- Ave. Duration
- 39 min
- Frequency
- 3 times a week
- Estimated price
- €6–13
- Website
- Trenitalia Intercity
Train from Caserta to Salerno
- Ave. Duration
- 39 min
- Frequency
- 3 times a week
- Estimated price
- €6–13
- Website
- Trenitalia Intercity
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Isernia to Casello - A1 Ingresso Caianello
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
Bus from San Salvo Marina to Pescara Airport
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- €3–5
- Schedules at
- satiautobus.com
Bus from San Salvo Marina to Pescara Airport
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- €3–5
- Schedules at
- satiautobus.com
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Casello - A1 Ingresso Caianello to Como
- Ave. Duration
- 6h 47m
- Frequency
- Once a week
- Estimated price
- €85–120
- Website
- Onebus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Isernia to Florence Villa Constanza Bus Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- €55–85
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Como
- Ave. Duration
- 5h 45m
- Frequency
- Twice daily
- Estimated price
- €30–50
- Website
- Flixbus
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Isernia to San Salvo Marina
- Ave. Duration
- 1h 17m
- Frequency
- Once a week
- Estimated price
- €4–6
- Schedules at
- atm-molise.it
Bus from Isernia to San Salvo Marina
- Ave. Duration
- 1h 17m
- Frequency
- Once a week
- Estimated price
- €4–6
- Schedules at
- atm-molise.it
- customerservices@terravision.eu
- Website
- TERRAVISION
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–23
- Website
- TERRAVISION
- Phone
- 035.319366
- ticket@orioshuttle.com
- Website
- orioshuttle.com
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–14
- Schedules at
- orioshuttle.com
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Getting to Milan from the airport
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Booking & Getting There
Isernia to Como bus services, operated by Società Autocooperative Trasporti Italiani S.p.A., arrive at Casello - A1 Ingresso Caianello station.
Isernia to Como train services, operated by Trenitalia, arrive at Roma Termini station.
Yes, the driving distance between Isernia to Como is 757 km. It takes approximately 7h 46m to drive from Isernia to Como.
Book your Isernia to Como train tickets online with Omio.
Book your Isernia to Como bus tickets online with Omio.
There are 5363+ hotels available in Como.









































