There are 4 ways to get from Irvine to San Diego - Santa Fe Depot by train (Amtrak), bus (Flixbus), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Irvine to San DiegoPacific Surfliner
3h 3m$29–35Train, bus
cheapest- Take the train from Tustin to OceansideOC Line / ...
- Take the bus from Oceanside Transit Center Stall 8 to UTC Transit Center101
3h 57m$13–32Line 59 bus, bus
- Take the bus from University-Ent 3773 Mariposa Villa to The Depot At Santa Ana Dock 359
- Take the bus from Santa Ana Bus Stop to San DiegoFlixBus 2017
3h 40m$18–37Drive 82.7 mi
- Drive from Irvine to San Diego - Santa Fe Depot82.7 mi
1h 27m$16–22
Irvine to San Diego - Santa Fe Depot by train and foot (Amtrak)
Questions & Answers
The cheapest way to get from Irvine to San Diego - Santa Fe Depot is to drive which costs $15 - $22 and takes 1h 27m.
The fastest way to get from Irvine to San Diego - Santa Fe Depot is to drive which takes 1h 27m and costs $15 - $22.
No, there is no direct bus from Irvine to San Diego - Santa Fe Depot. However, there are services departing from University-Ent 3773 Mariposa Villa and arriving at San Diego via Santa Ana Bus Stop. The journey, including transfers, takes approximately 3h 40m.
No, there is no direct train from Irvine to San Diego - Santa Fe Depot. However, there are services departing from Tustin and arriving at San Diego via Irvine. The journey, including transfers, takes approximately 3h 3m.
The distance between Irvine and San Diego - Santa Fe Depot is 89 miles. The road distance is 83.2 miles.
The best way to get from Irvine to San Diego - Santa Fe Depot without a car is to train which takes 3h 3m and costs $29 - $40.
It takes approximately 3h 3m to get from Irvine to San Diego - Santa Fe Depot, including transfers.
Irvine to San Diego - Santa Fe Depot bus services, operated by OCTA, depart from University-Ent 3773 Mariposa Villa station.
Irvine to San Diego - Santa Fe Depot train services, operated by Amtrak, depart from Irvine station.
The best way to get from Irvine to San Diego - Santa Fe Depot is to train which takes 3h 3m and costs $29 - $40. Alternatively, you can line 59 bus and bus, which costs $18 - $40 and takes 3h 40m.
What companies run services between Irvine, CA, USA and San Diego - Santa Fe Depot, CA, USA?
Amtrak operates a train from Irvine to San Diego every 2 hours. Tickets cost $25–30 and the journey takes 1h 52m. Alternatively, you can take a bus from University-Ent 3773 Mariposa Villa to San Diego - Santa Fe Depot via Santa Ana Bus Stop and San Diego in around 3h 40m.
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Irvine to San Diego
- Ave. Duration
- 1h 52m
- Frequency
- Every 2 hours
- Estimated price
- $25–30
- Website
- https://www.amtrak.com/home.html
- Phone
- (800) 371-LINK (5465)
- Website
- metrolinktrains.com
Train from Tustin to Oceanside
- Ave. Duration
- 57 min
- Frequency
- Every 4 hours
- Estimated price
- $9–12
- Website
- https://metrolinktrains.com
- Passenger
- $9–12
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from University-Ent 3773 Mariposa Villa to The Depot At Santa Ana Dock 3
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- octa.net
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Santa Ana Bus Stop to San Diego
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $16–35
- Schedules at
- flixbus.com
- Phone
- +1 760-966-6500
- Website
- gonctd.com
Bus from Oceanside Transit Center Stall 8 to UTC Transit Center
- Ave. Duration
- 1h 53m
- Frequency
- Hourly
- Estimated price
- $2–5
- Website
- https://gonctd.com
- Schedules at
- https://gonctd.com/schedules/
- Adult
- $2–5
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More Questions & Answers
Irvine to San Diego - Santa Fe Depot bus services, operated by OCTA, arrive at The Depot At Santa Ana Dock 3 station.
Irvine to San Diego - Santa Fe Depot train services, operated by Amtrak, arrive at San Diego station.
Yes, the driving distance between Irvine to San Diego - Santa Fe Depot is 83 miles. It takes approximately 1h 27m to drive from Irvine to San Diego - Santa Fe Depot.
There are 2219+ hotels available in San Diego - Santa Fe Depot.












