There are 6 ways to get from Irvine to Mexicali by train, bus, bus (Greyhound, Flixbus), car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Irvine to San Diego Old Town Transportation CenterPacific Surfliner
- Take the bus from Tijuana to Mexicali
7h 8m$846–1,458Bus
cheapest- Take the bus from Santa Ana to Tijuana - Plaza El MexicanoLos Angeles
- Take the bus from Tijuana to Mexicali
8h 47m$586–2,386Bus via Tijuana
- Take the bus from Santa Ana Bus Stop to San Ysidro Bus TerminalGreyhound US0831
- Take the bus from Tijuana to Mexicali
7h 20m$726–1,536Drive 312.5 km
- Drive from Irvine to Mexicali312.5 km
3h 38m$635–917Train to Los Angeles International Airport, fly to Imperial County Airport
- Take the train from Tustin to L.A. Union Station
- Fly from Los Angeles International Airport (LAX) to Imperial County Airport (IPL)LAX - IPL
4h 29m$2,001–3,330Fly John Wayne Airport Orange County to Yuma International Airport, bus
- Fly from John Wayne Airport Orange County (SNA) to Yuma International Airport (YUM)SNA - YUM
- Take the bus from San Luis Río Colorado to Mexicali
7h 4m$1,195–7,547
Irvine to Mexicali by bus and foot
Questions & Answers
The cheapest way to get from Irvine to Mexicali is to drive which costs $600 - $950 and takes 3h 38m.
The fastest way to get from Irvine to Mexicali is to drive which takes 3h 38m and costs $600 - $950.
No, there is no direct bus from Irvine to Mexicali. However, there are services departing from University-Ent 3773 Mariposa Villa and arriving at Mexicali via Santa Ana Bus Stop and Tijuana. The journey, including transfers, takes approximately 7h 20m.
The distance between Irvine and Mexicali is 344 km. The road distance is 312.5 km.
The best way to get from Irvine to Mexicali without a car is to train and bus which takes 7h 8m and costs $800 - $1500.
It takes approximately 7h 8m to get from Irvine to Mexicali, including transfers.
Irvine to Mexicali bus services, operated by Greyhound USA, depart from Santa Ana Bus Stop station.
Irvine to Mexicali bus services, operated by Greyhound USA, arrive at San Ysidro Bus Terminal station.
Yes, the driving distance between Irvine to Mexicali is 313 km. It takes approximately 3h 38m to drive from Irvine to Mexicali.
There are 91+ hotels available in Mexicali.
What companies run services between Irvine, CA, USA and Mexicali, Mexico?
You can take a bus from University-Ent 3773 Mariposa Villa to Mexicali via Santa Ana Bus Stop, San Ysidro Bus Terminal, and Tijuana in around 7h 20m.
- Website
- aa.com
Flights from John Wayne Airport Orange County to Yuma International Airport via Phoenix
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $1,000–6,500
- Website
- iflysouthern.com
Flights from Los Angeles International Airport to Imperial County Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $1,600–2,800
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Irvine to San Diego Old Town Transportation Center
- Ave. Duration
- 1h 38m
- Frequency
- Every 2 hours
- Estimated price
- $430–550
- Website
- https://www.amtrak.com/home.html
- Phone
- (800) 371-LINK (5465)
- Website
- metrolinktrains.com
Train from Tustin to L.A. Union Station
- Ave. Duration
- 1h
- Frequency
- Every 3 hours
- Estimated price
- $140–190
- Website
- https://metrolinktrains.com
- Passenger
- $140–190
- Phone
- +52 664 104 7400
- servicioalcliente@geb.mx
- Website
- abc.com.mx
Bus from Tijuana to Mexicali
- Ave. Duration
- 2h 5m
- Frequency
- Every 3 hours
- Estimated price
- $310–600
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
Bus from San Luis Río Colorado to Mexicali
- Ave. Duration
- 1h 30m
- Frequency
- 5 times a day
- Estimated price
- $120–320
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Santa Ana Bus Stop to San Ysidro Bus Terminal
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $550–900
- Website
- https://www.greyhound.com/
Bus from Santa Ana to Tijuana - Plaza El Mexicano
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $550–950
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Santa Ana Bus Stop to San Ysidro Bus Terminal
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $380–700
- Schedules at
- flixbus.com
- Phone
- +1-800-231-2222
- ifsr@greyhound.com
- Website
- greyhound.com.mx
Bus from Santa Ana to Tijuana - Plaza El Mexicano
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $350–900
- Schedules at
- greyhound.com.mx
- Phone
- +52 55 5141 4300
- contacto@odm.com.mx
- Website
- odm.com.mx
Bus from Tijuana to Mexicali
- Ave. Duration
- 2h 40m
- Frequency
- Every 20 minutes
- Estimated price
- $550–750
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
Bus from San Luis Río Colorado to Mexicali
- Ave. Duration
- 1h 20m
- Frequency
- Every 30 minutes
- Estimated price
- $360–490
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- autobuseselite.com.mx
Bus from Tijuana to Mexicali
- Ave. Duration
- 2h 17m
- Frequency
- 5 times a day
- Estimated price
- $420–650
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from San Luis Río Colorado to Mexicali
- Ave. Duration
- 1h 6m
- Frequency
- 4 times a day
- Estimated price
- $290–440
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +52 644 410 2444
- atencionaclientes@tufesa.com.mx
- Website
- tufesa.com.mx
Bus from Tijuana to Mexicali
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- $200–430
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $200–420
- Titanium
- $230–430
Bus from San Luis Río Colorado to Mexicali
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $80–310
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $80–310
- Titanium
- $95–310
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- chihuahuenses.com.mx
Bus from Tijuana to Mexicali
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $440–650
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
Bus from San Luis Río Colorado to Mexicali
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $230–350
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
- Phone
- +52 664 299 0487
- servicios@acnautobuses.com
- Website
- acnautobuses.com
Bus from Tijuana to Mexicali
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $900–1,400
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
Bus from San Luis Río Colorado to Mexicali
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $900–1,400
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
- Phone
- +52 55 4440 3187
- contacto@geb.mx
- Website
- autobusesaguacaliente.mx
Bus from Tijuana to Mexicali
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $210–290
- Schedules at
- autobusesaguacaliente.mx
- Book at
- autobusesaguacaliente.mx
Want to know more about travelling around Mexico
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide









































