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How to get fromIrvine to Indianaby plane, train, bus, bus (Greyhound, Flixbus) or car

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There are 7 ways to get from Irvine to Indiana by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Chicago O'Hare International Airport, train

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Chicago O'Hare International Airport (ORD)plane plane SNA - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 6m
    $140–525

  2. Train to Los Angeles International Airport, fly to Chicago O'Hare International Airport, train

    cheapest
    1. Take the train from Tustin to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to Chicago O'Hare International Airport (ORD)plane plane LAX - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    8h 31m
    $113–399

  3. Train, bus

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the bus from Chicago Bus Station to Indianapolisbus bus FlixBus N2640 / ...
    2d 1h
    $220–1,577

  4. Bus

    1. Take the bus from Anaheim Regional Transportation Intermodal Center to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    2d 2h
    $160–433

  5. Drive 2,049 mi

    1. Drive from Irvine to Indianapoliscar car 2,049 mi
    32h 48m
    $374–541

  6. Train to Los Angeles International Airport, fly to Indianapolis

    1. Take the train from Tustin to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to Indianapolis (IND)plane plane LAX - IND
    7h 35m
    $181–517

  7. Train to Los Angeles International Airport, fly to Chicago Midway International Airport, train

    1. Take the train from Tustin to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to Chicago Midway International Airport (MDW)plane plane LAX - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    8h 23m
    $138–589

Irvine to Indiana by train, foot, and bus

Calendar7Weekly Services
Duration2d 1hAverage Duration
Ticket$220Cheapest Price
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Questions & Answers

What companies run services between Irvine, CA, USA and Indiana, USA?

You can take a bus from Main-Harvard to Indianapolis Union Station via Artic - Dock 4, Anaheim Regional Transportation Intermodal Center, Los Angeles Union Station, and St Louis Bus Station in around 2d 2h.

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