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How to get fromIrvine to Indianaby plane, train, bus (Greyhound), train (Amtrak) or car

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There are 7 ways to get from Irvine to Indiana by plane, train, bus (Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Chicago O'Hare International Airport, train

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Chicago O'Hare International Airport (ORD)planeSNA - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain
    6h 5m
    $133–473

  2. Train to Los Angeles International Airport, fly to Chicago O'Hare International Airport, train

    cheapest
    1. Take the train from Tustin to L.A. Union Stationtrain
    2. Fly from Los Angeles International Airport (LAX) to Chicago O'Hare International Airport (ORD)planeLAX - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain
    8h 36m
    $113–389

  3. Bus (Greyhound)

    1. Take the bus from Anaheim to Los Angeles Union Stationbus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
    2d 1h
    $205–487

  4. Train (Amtrak)

    1. Take the train from Fullerton Amtrak Station to Chicago Union StationtrainSouthwest Chief
    2. Take the train from Chicago Union Station to IndianapolistrainCardinal
    2d 2h
    $205–1,782

  5. Drive 2,049 mi

    1. Drive from Irvine to Indianapoliscar2,049 mi
    32h 38m
    $374–541

  6. Train to Los Angeles International Airport, fly to Indianapolis

    1. Take the train from Tustin to L.A. Union Stationtrain
    2. Fly from Los Angeles International Airport (LAX) to Indianapolis (IND)planeLAX - IND
    7h 39m
    $191–507

  7. Train to Los Angeles International Airport, fly to Chicago Midway International Airport, train

    1. Take the train from Tustin to L.A. Union Stationtrain
    2. Fly from Los Angeles International Airport (LAX) to Chicago Midway International Airport (MDW)planeLAX - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain
    8h 18m
    $138–519

Irvine to Indiana by bus (Greyhound)

Calendar11Weekly Buses
Duration2d 1hAverage Duration
Ticket$205Cheapest Price
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Questions & Answers

What companies run services between Irvine, CA, USA and Indiana, USA?

You can take a bus from Main-Harvard to Indianapolis Union Station via Artic - Dock 4, Anaheim, Los Angeles Union Station, and St Louis Bus Station in around 2d 1h. Alternatively, you can take a train from Tustin to Indianapolis via Fullerton, Fullerton Amtrak Station, and Chicago Union Station in around 2d 2h.

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Need to know: Greyhound

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