There are 7 ways to get from Irvine to Duke University by plane, bus (Greyhound, Flixbus), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly John Wayne Airport Orange County to Raleigh-Durham International Airport
best- Fly from John Wayne Airport Orange County (SNA) to Raleigh-Durham International Airport (RDU)plane SNA - RDU
7h 19m$176–737Bus
- Take the bus from Anaheim to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Durhambus
2d 12h$246–603Train, bus
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Raleigh Union Stationtrain
- Take the bus from Union Station - Bus Platform A to Chapel Dr at Duke University Rdbus
2d 23h$325–1,897Drive 2,481.1 mi
- Drive from Irvine to Duke Universitycar 2,481.1 mi
40h 40m$453–655Train to Los Angeles International Airport, fly to Raleigh-Durham International Airport
- Take the train from Tustin to L.A. Union Stationtrain
- Fly from Los Angeles International Airport (LAX) to Raleigh-Durham International Airport (RDU)plane LAX - RDU
9h 31m$190–579Fly John Wayne Airport Orange County to Charlotte Douglas International Airport, train
- Fly from John Wayne Airport Orange County (SNA) to Charlotte Douglas International Airport (CLT)plane SNA - CLT
- Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain
9h 49m$311–740Fly John Wayne Airport Orange County to Piedmont Triad International Airport, train
- Fly from John Wayne Airport Orange County (SNA) to Piedmont Triad International Airport (GSO)plane SNA - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
10h 42m$251–977
Irvine to Duke University by bus and foot
Questions & Answers
The cheapest way to get from Irvine to Duke University is to train and fly which costs $190 - $600 and takes 9h 31m.
The fastest way to get from Irvine to Duke University is to fly which takes 7h 19m and costs $170 - $750.
No, there is no direct bus from Irvine to Duke University. However, there are services departing from Main-Harvard and arriving at Flowers Dr at Duke Gardens via Anaheim, Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station and Durham Station. The journey, including transfers, takes approximately 2 days 12h.
The distance between Irvine and Duke University is 2238 miles. The road distance is 2495.6 miles.
The best way to get from Irvine to Duke University without a car is to bus which takes 2 days 12h and costs $240 - $650.
It takes approximately 7h 19m to get from Irvine to Duke University, including transfers.
Irvine to Duke University bus services, operated by Greyhound Mexico, depart from Anaheim station.
The best way to get from Irvine to Duke University is to fly which takes 7h 19m and costs $170 - $750. Alternatively, you can bus, which costs $240 - $650 and takes 2 days 12h.
Irvine to Duke University bus services, operated by Greyhound Mexico, arrive at Los Angeles Union Station.
Duke University is 3h ahead of Irvine. It is currently 2:08 AM in Irvine and 5:08 AM in Duke University.
What companies run services between Irvine, CA, USA and Duke University, NC, USA?
Breeze Airways, Southwest Airlines, and two other airlines fly from John Wayne Airport Orange County (SNA) to Raleigh-Durham International Airport (RDU) 4 times a day. Alternatively, you can take a bus from Main-Harvard to Duke University via Artic - Dock 4, Anaheim, Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station, Durham, Durham Station, and Flowers Dr at Duke Gardens in around 2d 12h.
- Website
- delta.com
Flights from John Wayne Airport Orange County to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $170–750
Flights from Los Angeles International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $130–600
Flights from Los Angeles International Airport to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $140–600
Flights from Los Angeles International Airport to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 8h 59m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–600
Flights from John Wayne Airport Orange County to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 7h 9m
- When
- Every day
- Estimated price
- $150–700
Flights from John Wayne Airport Orange County to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 7h 20m
- When
- Every day
- Estimated price
- $220–1,000
Flights from John Wayne Airport Orange County to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 7h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,100
- Website
- aa.com
Flights from John Wayne Airport Orange County to Raleigh-Durham International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $170–750
Flights from Los Angeles International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 4h 43m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–600
Flights from John Wayne Airport Orange County to Charlotte Douglas International Airport
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $150–650
Flights from John Wayne Airport Orange County to Charlotte Douglas International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 48m
- When
- Every day
- Estimated price
- $150–650
Flights from John Wayne Airport Orange County to Piedmont Triad International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 7m
- When
- Every day
- Estimated price
- $220–1,000
Flights from John Wayne Airport Orange County to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 7h 58m
- When
- Every day
- Estimated price
- $220–950
Flights from John Wayne Airport Orange County to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 8h 5m
- When
- Every day
- Estimated price
- $230–1,000
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Raleigh-Durham International Airport via Dallas
- Ave. Duration
- 6h 20m
- When
- Saturday
- Estimated price
- $170–750
Flights from Los Angeles International Airport to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 8h 40m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–600
Flights from Los Angeles International Airport to Raleigh-Durham International Airport via Kansas City
- Ave. Duration
- 9h 5m
- When
- Sunday
- Estimated price
- $140–600
Flights from John Wayne Airport Orange County to Charlotte Douglas International Airport via Dallas
- Ave. Duration
- 6h 10m
- When
- Saturday
- Estimated price
- $150–650
- Website
- united.com
Flights from John Wayne Airport Orange County to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $230–1,000
Flights from John Wayne Airport Orange County to Piedmont Triad International Airport via Newark
- Ave. Duration
- 11h 54m
- When
- Every day
- Estimated price
- $280–1,200
- Website
- flybreeze.com
Flights from John Wayne Airport Orange County to Raleigh-Durham International Airport
- Ave. Duration
- 5h 5m
- When
- Monday and Friday
- Estimated price
- $310–1,200
- Website
- flyfrontier.com
Flights from Los Angeles International Airport to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 6h 42m
- When
- Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $140–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $180–1,500
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 23h 56m
- Frequency
- Once daily
- Estimated price
- $140–390
- Website
- https://www.amtrak.com/home.html
Train from Charlotte Amtrak Station to Durham Amtrak Station
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a day
- Estimated price
- $28–32
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $11–13
- Website
- https://www.amtrak.com/home.html
- Phone
- (800) 371-LINK (5465)
- Website
- metrolinktrains.com
Train from Tustin to L.A. Union Station
- Ave. Duration
- 1h
- Frequency
- Every 3 hours
- Estimated price
- $8–11
- Website
- https://metrolinktrains.com
- Passenger
- $8–11
- Phone
- +1-800-231-2222
- ifsr@greyhound.com
- Website
- greyhound.com.mx
Bus from Anaheim to Los Angeles Union Station
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $8–40
- Schedules at
- greyhound.com.mx
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Los Angeles Union Station to Dallas Bus Station
- Ave. Duration
- 29h 15m
- Frequency
- Twice daily
- Estimated price
- $110–260
- Website
- https://www.greyhound.com/
Bus from Dallas Bus Station to Atlanta Bus Station
- Ave. Duration
- 18h 5m
- Frequency
- 3 times a day
- Estimated price
- $75–170
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Durham
- Ave. Duration
- 8h 20m
- Frequency
- Once daily
- Estimated price
- $55–130
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Atlanta Bus Station to Durham
- Ave. Duration
- 7h 20m
- Frequency
- 3 times a day
- Estimated price
- $50–85
- Schedules at
- flixbus.com
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from Union Station - Bus Platform A to Chapel Dr at Duke University Rd
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Irvine to Duke University is 2496 miles. It takes approximately 40h 40m to drive from Irvine to Duke University.
There are 276+ hotels available in Duke University.

















