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How to get fromIrvine to Buffaloby plane, train (Amtrak), bus (Greyhound), car or train

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There are 5 ways to get from Irvine to Buffalo by plane, train (Amtrak), bus (Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Wayne Airport Orange County

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Buffalo Niagara International Airport (BUF)plane plane SNA - BUF
    7h 26m
    $437–1,876

  2. Train to Los Angeles International Airport, fly

    cheapest
    1. Take the train from Tustin to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to Buffalo Niagara International Airport (BUF)plane plane LAX - BUF
    8h 36m
    $358–1,527

  3. Train (Amtrak)

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    2d 8h
    $766–1,814

  4. Bus

    1. Take the bus from Anaheim to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Columbusbus bus
    4. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    2d 14h
    $460–885

  5. Drive 2,529.4 mi

    1. Drive from Irvine to Buffalocar car 2,529.4 mi
    40h 17m
    $462–667

Irvine to Buffalo by train (Amtrak)

Calendar7Weekly Trains
Duration2d 8hAverage Duration
Ticket$766Cheapest Price
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Questions & Answers

What companies run services between Irvine, CA, USA and Buffalo, NY, USA?

Delta, United Airlines, and two other airlines fly from John Wayne Airport Orange County (SNA) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a train from Tustin to Buffalo via Fullerton, Fullerton Amtrak Station, Chicago Union Station, and Buffalo Depew Station in around 2d 8h.

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