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How to get fromIowa to Tupeloby plane, bus (Greyhound, Flixbus), car, bus, or train

Find Transport to Tupelo

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There are 5 ways to get from Iowa to Tupelo by plane, bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Tupelo Regional Airport (TUP)plane plane DSM - TUP
    6h 59m
    $127–539

  2. Fly from Omaha

    cheapest
    1. Fly from Omaha (OMA) to Tupelo Regional Airport (TUP)plane plane OMA - TUP
    7h 26m
    $117–521

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    17h 45m
    $129–252

  4. Drive 681.7 mi

    1. Drive from Des Moines to Tupelocar car 681.7 mi
    12h 45m
    $125–180

  5. Bus, train

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    20h 9m
    $198–374

Des Moines (DSM) to Tupelo Regional Airport (TUP) flights

Calendar20Weekly Planes
Duration8h 23mAverage Duration
Ticket$97Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Tupelo.ExpandLaunch map view
  • Distance: 578.9 mi
  • Duration: 6h 59m

What companies run services between Iowa, USA and Tupelo, MS, USA?

American Airlines, Corporate Flight Management Inc, and three other airlines fly from Des Moines (DSM) to Tupelo Regional Airport (TUP) 3 times a day. Alternatively, you can take a vehicle from Des Moines to Tupelo via Des Moines, St Louis Bus Station, Memphis Bus Station, and Tupelo in around 17h 45m.

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