Rome2Rio

How to get fromIowa to Tupeloby plane, car, bus (Greyhound), bus or train

Find Transport to Tupelo

See all options

There are 7 ways to get from Iowa to Tupelo by plane, car, bus (Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Quad City International Airport to Golden Triangle Regional Airport, drive

    best
    1. Fly from Quad City International Airport (MLI) to Golden Triangle Regional Airport (GTR)plane plane MLI - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    10h 19m
    $93–439

  2. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    17h 20m
    $111–342

  3. Drive 681.7 mi

    1. Drive from Des Moines to Tupelocar car 681.7 mi
    12h 54m
    $125–180

  4. Fly Des Moines to Tupelo Regional Airport

    1. Fly from Des Moines (DSM) to Tupelo Regional Airport (TUP)plane plane DSM - TUP
    6h 30m
    $214–1,041

  5. Fly Omaha to Tupelo Regional Airport

    1. Fly from Omaha (OMA) to Tupelo Regional Airport (TUP)plane plane OMA - TUP
    7h 49m
    $209–1,123

  6. Fly Quad City International Airport to Tupelo Regional Airport

    1. Fly from Quad City International Airport (MLI) to Tupelo Regional Airport (TUP)plane plane MLI - TUP
    8h 50m
    $118–622

  7. Bus, train

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    20h 12m
    $136–372

Quad City International Airport (MLI) to Golden Triangle Regional Airport (GTR) flights

Calendar21Weekly Planes
Duration10h 20mAverage Duration
Ticket$80Cheapest Price
See schedules

Questions & Answers

What companies run services between Iowa, USA and Tupelo, MS, USA?

You can take a vehicle from Des Moines to Tupelo via Des Moines, Kansas City, Memphis Bus Station, and Tupelo in around 17h 20m. Alternatively, American Airlines, Corporate Flight Management Inc, and three other airlines fly from Des Moines (DSM) to Tupelo Regional Airport (TUP) twice daily.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Iowa

Trips to Tupelo

Popular routes