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How to get fromIowa to Tupeloby plane, car, bus (Greyhound, Flixbus), bus (Amtrak, Flixbus, Greyhound), bus or train

Find Transport to Tupelo

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There are 6 ways to get from Iowa to Tupelo by plane, car, bus (Greyhound, Flixbus), bus (Amtrak, Flixbus, Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport, drive

    best
    1. Fly from Des Moines (DSM) to Golden Triangle Regional Airport (GTR)planeDSM - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
    8h 35m
    $169–788

  2. Drive 681.7 mi

    cheapest
    1. Drive from Des Moines to Tupelocar681.7 mi
    12h 50m
    $125–180

  3. Bus

    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to St Louisbus
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus
    4. Take the bus from Memphis Bus Station to Tupelobus
    17h 44m
    $171–419

  4. Fly to Tupelo Regional Airport

    1. Fly from Des Moines (DSM) to Tupelo Regional Airport (TUP)planeDSM - TUP
    4h 9m
    $204–991

  5. Bus via Springfield

    1. Take the bus from Des Moines to Galesburgbus
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus
    3. Take the bus from Springfield SMTD Transfer Center to Memphis Bus Stationbus
    4. Take the bus from Memphis Bus Station to Tupelobus
    18h 40m

  6. Bus, train

    1. Take the bus from Des Moines to Kansas Citybus
    2. Take the train from Kansas City to St. Louistrain
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus
    4. Take the bus from Memphis Bus Station to Tupelobus
    20h 10m
    $137–387

Des Moines (DSM) to Golden Triangle Regional Airport (GTR) flights

Calendar25Weekly Planes
Duration9h 6mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Tupelo, MS, USA?

You can take a bus from Des Moines to Tupelo via Burlington, St Louis Bus Station, Memphis Bus Station, and Tupelo in around 17h 44m. Alternatively, Allegiant Air, Corporate Flight Management Inc, and three other airlines fly from Des Moines (DSM) to Tupelo Regional Airport (TUP) twice daily.

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