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How to get fromIowa to Tupeloby plane, bus (Greyhound, Flixbus), car, bus (Greyhound), bus, or train

Find Transport to Tupelo

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There are 6 ways to get from Iowa to Tupelo by plane, bus (Greyhound, Flixbus), car, bus (Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Tupelo Regional Airport (TUP)plane plane DSM - TUP
    5h 3m
    $132–589

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Tupelo Regional Airport (TUP)plane plane MLI - TUP
    9h 26m
    $86–380

  3. Bus via St. Louis

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    16h 55m
    $130–257

  4. Drive 681.7 mi

    1. Drive from Des Moines to Tupelocar car 681.7 mi
    12h 45m
    $125–180

  5. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    17h 25m
    $195–287

  6. Bus, train

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    19h 23m
    $205–392

Des Moines (DSM) to Tupelo Regional Airport (TUP) flights

Calendar11Weekly Planes
Duration6h 51mAverage Duration
Ticket$100Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Tupelo.ExpandLaunch map view
  • Distance: 578.9 mi
  • Duration: 5h 3m

What companies run services between Iowa, USA and Tupelo, MS, USA?

American Airlines, Corporate Flight Management Inc, and four other airlines fly from Des Moines (DSM) to Tupelo Regional Airport (TUP) twice daily. Alternatively, you can take a vehicle from Des Moines to Tupelo via Des Moines, St Louis Bus Station, Memphis Bus Station, and Tupelo in around 16h 55m.

Airlines
Train operators
Bus operators

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