There are 6 ways to get from Iowa to Tupelo by plane, bus (Greyhound, Flixbus), car, bus (Greyhound), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines
best- Fly from Des Moines (DSM) to Tupelo Regional Airport (TUP)plane DSM - TUP
4h 54m$132–639Drive 681.7 mi
cheapest- Drive from Des Moines to Tupelocar 681.7 mi
12h 45m$125–180Bus via St. Louis
- Take the bus from Des Moines to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
16h 55m$136–279Fly from Omaha
- Fly from Omaha (OMA) to Tupelo Regional Airport (TUP)plane OMA - TUP
7h 31m$147–771Bus
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
17h 25m$196–294Bus, train
- Take the bus from Des Moines to Kansas Citybus
- Take the train from Kansas City to St. Louistrain
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
19h 23m$196–394
Des Moines (DSM) to Tupelo Regional Airport (TUP) flights
Questions & Answers
The cheapest way to get from Iowa to Tupelo is to drive which costs $120 - $180 and takes 12h 45m.
The fastest way to get from Iowa to Tupelo is to fly which takes 4h 54m and costs $130 - $650.
The distance between Iowa and Tupelo is 582 miles. The road distance is 685.7 miles.
The best way to get from Iowa to Tupelo without a car is to bus via St. Louis which takes 16h 55m and costs $130 - $280.
It takes approximately 4h 54m to get from Iowa to Tupelo, including transfers.
The best way to get from Iowa to Tupelo is to fly which takes 4h 54m and costs $130 - $650. Alternatively, you can bus via St. Louis, which costs $130 - $280 and takes 16h 55m.
Yes, the driving distance between Iowa to Tupelo is 686 miles. It takes approximately 12h 45m to drive from Iowa to Tupelo.
There are 31+ hotels available in Tupelo.
What companies run services between Iowa, USA and Tupelo, MS, USA?
Allegiant Air, Corporate Flight Management Inc, and four other airlines fly from Des Moines (DSM) to Tupelo Regional Airport (TUP) 3 times a day. Alternatively, you can take a vehicle from Des Moines to Tupelo via Des Moines, St Louis Bus Station, Memphis Bus Station, and Tupelo in around 16h 55m.
- Website
- contouraviation.com
Flights from Des Moines to Tupelo Regional Airport via Nashville
- Ave. Duration
- 4h 35m
- When
- Sunday
- Estimated price
- $100–600
Flights from Des Moines to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 44m
- When
- Sunday
- Estimated price
- $150–750
Flights from Des Moines to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $150–750
Flights from Des Moines to Tupelo Regional Airport via Chicago Midway, Nashville
- Ave. Duration
- 6h 55m
- When
- Monday to Saturday
- Estimated price
- $120–650
Flights from Des Moines to Tupelo Regional Airport via Chicago O'Hare, Nashville
- Ave. Duration
- 7h 23m
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to Tupelo Regional Airport via Minneapolis, Nashville
- Ave. Duration
- 8h 5m
- When
- Sunday
- Estimated price
- $150–750
Flights from Omaha to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–850
Flights from Omaha to Tupelo Regional Airport via Nashville
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $130–750
Flights from Omaha to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 7h 18m
- When
- Every day
- Estimated price
- $180–900
Flights from Omaha to Tupelo Regional Airport via Chicago Midway, Nashville
- Ave. Duration
- 7h 5m
- When
- Monday to Saturday
- Estimated price
- $160–800
Flights from Omaha to Tupelo Regional Airport via Chicago O'Hare, Nashville
- Ave. Duration
- 7h 22m
- When
- Sunday
- Estimated price
- $160–800
Flights from Omaha to Tupelo Regional Airport via Minneapolis, Nashville
- Ave. Duration
- 9h 35m
- When
- Sunday
- Estimated price
- $180–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $75–170
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to St Louis Bus Station
- Ave. Duration
- 8h 15m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $16–35
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $35–65
- Schedules at
- flixbus.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–75
Bus from Kansas City to Memphis Bus Station
- Ave. Duration
- 10h
- Frequency
- 4 times a week
- Estimated price
- $110–160
- Book at
- https://www.jeffersonlines.com
- Adult
- $110–160
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