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How to get fromIowa to Pittsburghby plane, bus, train, bus (Greyhound, Flixbus), car or bus (Flixbus)

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There are 10 ways to get from Iowa to Pittsburgh by plane, bus, train, bus (Greyhound, Flixbus), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Pittsburgh International Airport (PIT)planeDSM - PIT
    5h 9m
    $138–721

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Pittsburgh International Airport (PIT)planeMLI - PIT
    8h 28m
    $67–372

  3. Bus, train

    1. Take the bus from Des Moines to ChicagobusDes Moines
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak StationtrainFloridian
    17h 49m
    $146–354

  4. Bus

    1. Take the bus from Des Moines to ChicagobusOmaha
    2. Take the bus from Chicago Bus Station to Pittsburgh Intermodal StationbusGreyhound US0164
    18h 38m
    $122–282

  5. Drive 776 mi

    1. Drive from Des Moines to Pittsburghcar776 mi
    12h 42m
    $142–205

  6. Fly from The Eastern Iowa Airport

    1. Fly from The Eastern Iowa Airport (CID) to Pittsburgh International Airport (PIT)planeCID - PIT
    7h 16m
    $92–420

  7. Fly from Omaha

    1. Fly from Omaha (OMA) to Pittsburgh International Airport (PIT)planeOMA - PIT
    7h 54m
    $143–753

  8. Bus, train via 7Th St / Locust St, Dsm

    1. Take the bus from Des Moines to ChicagobusOmaha
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak StationtrainFloridian
    18h 2m
    $157–352

  9. Bus, train via Galesburg

    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to Galesburgbus
    3. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
    4. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain
    19h 20m
    $180–412

  10. Bus via Auburn Gresham

    1. Take the bus from Des Moines to ChicagobusDes Moines
    2. Take the bus from Chicago to Pittsburgh Intermodal StationbusFlixBus N2640
    19h 25m
    $120–274

Iowa to Pittsburgh by bus, foot, and train

Calendar7Weekly Services
Duration17h 49mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Pittsburgh, PA, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to Pittsburgh International Airport (PIT) every 3 hours. Alternatively, you can take a bus from Pennsylvania Ave / E University Ave to Pittsburgh Intermodal Station via 7Th St / Locust St, Dsm, Des Moines, and Chicago Bus Station in around 18h 38m.

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