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How to get fromIowa to Pittsburghby plane, bus, train, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Find Transport to Pittsburgh

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There are 7 ways to get from Iowa to Pittsburgh by plane, bus, train, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Pittsburgh International Airport (PIT)plane plane DSM - PIT
    5h 15m
    $129–673

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Pittsburgh International Airport (PIT)plane plane MLI - PIT
    7h 26m
    $77–452

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    17h 44m
    $168–375

  4. Bus via Chicago

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago to Pittsburgh Intermodal Stationbus bus FlixBus N2640
    19h 31m
    $143–223

  5. Drive  776 mi

    1. Drive from Des Moines to Pittsburghcar car 776 mi
    12h 49m
    $142–205

  6. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train
    18h 55m
    $188–440

  7. Bus (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Pittsburgh Intermodal Stationbus bus Greyhound US0421
    19h 35m
    $133–220

Des Moines (DSM) to Pittsburgh International Airport (PIT) flights

Calendar147Weekly Planes
Duration5h 6mAverage Duration
Ticket$118Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Pittsburgh.ExpandLaunch map view
  • Distance: 733.3 mi
  • Duration: 5h 15m

What companies run services between Iowa, USA and Pittsburgh, PA, USA?

Southwest Airlines, Delta, and three other airlines fly from Des Moines (DSM) to Pittsburgh International Airport (PIT) hourly. Alternatively, you can take a vehicle from Des Moines to Pittsburgh Intermodal Station via Des Moines, Chicago Bus Station, Jefferson & Harrison, Washington & State, Lake, 95th, and Chicago in around 19h 31m.

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