There are 7 ways to get from Iowa to Pensacola by plane, bus (Greyhound, Flixbus), bus, train, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Des Moines to Pensacola International Airport
best- Fly from Des Moines (DSM) to Pensacola International Airport (PNS)plane DSM - PNS
5h 42m$180–923Fly Quad City International Airport to Pensacola International Airport
cheapest- Fly from Quad City International Airport (MLI) to Pensacola International Airport (PNS)plane MLI - PNS
8h$94–494Bus
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to New Orleans Bus Stationbus
- Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus
- Take the bus from Biloxi to Pensacolabus
30h 51m$177–498Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain
- Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus
- Take the bus from Biloxi to Pensacolabus
34h 17m$334–688Drive 1,012.2 mi
- Drive from Des Moines to Pensacolacar 1,012.2 mi
19h 18m$185–267Fly Quad City International Airport to Destin–Fort Walton Beach Airport, taxi
- Fly from Quad City International Airport (MLI) to Destin–Fort Walton Beach Airport (VPS)plane MLI - VPS
- Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi
8h 25m$197–562Fly Omaha to Pensacola International Airport
- Fly from Omaha (OMA) to Pensacola International Airport (PNS)plane OMA - PNS
7h 52m$155–805
Des Moines (DSM) to Pensacola International Airport (PNS) flights
Questions & Answers
The cheapest way to get from Iowa to Pensacola is to drive which costs $180 - $270 and takes 19h 18m.
The fastest way to get from Iowa to Pensacola is to fly which takes 5h 42m and costs $180 - $950.
The distance between Iowa and Pensacola is 860 miles. The road distance is 1018.1 miles.
The best way to get from Iowa to Pensacola without a car is to bus which takes 30h 51m and costs $170 - $500.
It takes approximately 5h 42m to get from Iowa to Pensacola, including transfers.
The best way to get from Iowa to Pensacola is to fly which takes 5h 42m and costs $180 - $950. Alternatively, you can bus, which costs $170 - $500 and takes 30h 51m.
Yes, the driving distance between Iowa to Pensacola is 1018 miles. It takes approximately 19h 18m to drive from Iowa to Pensacola.
There are 1542+ hotels available in Pensacola.
What companies run services between Iowa, USA and Pensacola, FL, USA?
Delta, American Airlines, and Southwest Airlines fly from Des Moines (DSM) to Pensacola International Airport (PNS) every 4 hours. Alternatively, you can take a vehicle from Des Moines to Pensacola via Des Moines, Kansas City, Memphis Bus Station, New Orleans Bus Station, Biloxi Transit Center, and Biloxi in around 30h 51m.
- Website
- aa.com
Flights from Des Moines to Pensacola International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Quad City International Airport to Pensacola International Airport via Charlotte
- Ave. Duration
- 6h 54m
- When
- Every day
- Estimated price
- $110–550
Flights from Quad City International Airport to Pensacola International Airport via Chicago O'Hare
- Ave. Duration
- 6h 39m
- When
- Every day
- Estimated price
- $95–490
Flights from Quad City International Airport to Pensacola International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 42m
- When
- Every day
- Estimated price
- $110–600
Flights from Quad City International Airport to Destin–Fort Walton Beach Airport via Chicago O'Hare
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $80–420
Flights from Quad City International Airport to Destin–Fort Walton Beach Airport via Charlotte
- Ave. Duration
- 7h 50m
- When
- Every day
- Estimated price
- $90–450
Flights from Quad City International Airport to Destin–Fort Walton Beach Airport via Dallas/Ft.Worth
- Ave. Duration
- 9h 1m
- When
- Every day
- Estimated price
- $100–490
Flights from Omaha to Pensacola International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 13m
- When
- Every day
- Estimated price
- $180–900
- Website
- delta.com
Flights from Des Moines to Pensacola International Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $180–950
Flights from Quad City International Airport to Pensacola International Airport via Atlanta
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $90–490
Flights from Quad City International Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $75–410
Flights from Omaha to Pensacola International Airport via Atlanta
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $170–850
- Website
- southwest.com
Flights from Des Moines to Pensacola International Airport via Chicago Midway
- Ave. Duration
- 5h 55m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $190–1,000
Flights from Des Moines to Pensacola International Airport via St. Louis
- Ave. Duration
- 6h 55m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $160–900
Flights from Omaha to Pensacola International Airport via St. Louis
- Ave. Duration
- 3h 55m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $150–800
Flights from Omaha to Pensacola International Airport via Nashville
- Ave. Duration
- 4h 45m
- When
- Monday to Wednesday
- Estimated price
- $160–850
Flights from Omaha to Pensacola International Airport via Dallas
- Ave. Duration
- 4h 25m
- When
- Thursday and Friday
- Estimated price
- $180–900
Flights from Omaha to Pensacola International Airport via Houston Hobby Apt
- Ave. Duration
- 5h
- When
- Saturday
- Estimated price
- $190–950
Flights from Omaha to Pensacola International Airport via Chicago Midway
- Ave. Duration
- 7h 20m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $180–900
- Website
- united.com
Flights from Quad City International Airport to Pensacola International Airport via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $95–490
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 19h 42m
- Frequency
- Once daily
- Estimated price
- $210–480
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Bus from Kansas City to Memphis Bus Station
- Ave. Duration
- 10h
- Frequency
- 4 times a week
- Estimated price
- $45–170
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Memphis Bus Station to New Orleans Bus Station
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from New Orleans Bus Station to Biloxi Transit Center
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $15–28
- Website
- https://www.greyhound.com/
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $55–100
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Memphis Bus Station to New Orleans Bus Station
- Ave. Duration
- 7h 30m
- Frequency
- 5 times a week
- Estimated price
- $45–85
- Schedules at
- flixbus.com
Bus from New Orleans Bus Station to Biloxi Transit Center
- Ave. Duration
- 1h 25m
- Frequency
- 6 times a week
- Estimated price
- $10–19
- Schedules at
- flixbus.com
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Biloxi to Pensacola
- Ave. Duration
- 2h 23m
- Frequency
- Once daily
- Estimated price
- $50–70
- Schedules at
- omnibusexpress.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide











