There are 10 ways to get from Iowa to Ohio by plane, bus (Flixbus), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Quad City International Airport to Cleveland-Hopkins International Airport
best- Fly from Quad City International Airport (MLI) to Cleveland-Hopkins International Airport (CLE)MLI - CLE
6h 34m$80–465Fly Quad City International Airport to John Glenn Columbus International Airport
cheapest- Fly from Quad City International Airport (MLI) to John Glenn Columbus International Airport (CMH)MLI - CMH
7h 1m$69–395Bus via Indianapolis
- Take the bus from Des Moines to Indianapolis Union StationDenver
- Take the bus from Indianapolis to ColumbusFlixBus N2640 / ...
14h 9m$113–235Bus, train
- Take the bus from Des Moines to Burlington
- Take the bus from Burlington to Galesburg
- Take the train from Galesburg Amtrak Station to Chicago Union Station
- Take the train from Chicago Union Station to Toledo
- Take the bus from Toledo to Columbus - Mound St
17h 44m$148–402Drive 619.5 mi
- Drive from Des Moines to Columbus619.5 mi
11h 21m$114–164Fly Des Moines to Detroit, bus
- Fly from Des Moines (DSM) to Detroit (DTW)DSM - DTW
- Take the bus from Dearborn to Toledo
5h 30mFly Quad City International Airport to Dayton
- Fly from Quad City International Airport (MLI) to Dayton (DAY)MLI - DAY
8h 48m$99–604Fly Quad City International Airport to Covington
- Fly from Quad City International Airport (MLI) to Covington (CVG)MLI - CVG
7h 36m$105–607Bus
- Take the bus from Des Moines to Indianapolis Union StationDenver
- Take the bus from Indianapolis Union Station to ColumbusGreyhound US0421
15h 10m$113–220Bus #2
- Take the bus from Des Moines to ChicagoDes Moines
- Take the bus from Chicago to Columbus - Mound StChicago
16h 5m$86–234
Iowa to Ohio by bus and foot
Questions & Answers
The cheapest way to get from Iowa to Ohio is to drive which costs $110 - $170 and takes 11h 21m.
The fastest way to get from Iowa to Ohio is to fly which takes 6h 34m and costs $80 - $470.
No, there is no direct bus from Iowa to Ohio. However, there are services departing from Des Moines and arriving at Columbus via Indianapolis. The journey, including transfers, takes approximately 14h 9m.
The distance between Iowa and Ohio is 476 miles. The road distance is 623.1 miles.
The best way to get from Iowa to Ohio without a car is to bus via Indianapolis which takes 14h 9m and costs $110 - $240.
It takes approximately 6h 34m to get from Iowa to Ohio, including transfers.
Iowa to Ohio bus services, operated by Burlington Trailways, depart from Des Moines station.
The best way to get from Iowa to Ohio is to fly which takes 6h 34m and costs $80 - $470. Alternatively, you can bus via Indianapolis, which costs $110 - $240 and takes 14h 9m.
Iowa to Ohio bus services, operated by Burlington Trailways, arrive at Indianapolis Union Station.
Ohio is 1h ahead of Iowa. It is currently 8:51 PM in Iowa and 9:51 PM in Ohio.
What companies run services between Iowa, USA and Ohio, USA?
American Airlines, United Airlines, and Delta fly from Quad City International Airport (MLI) to Cleveland-Hopkins International Airport (CLE) every 3 hours. Alternatively, you can take a bus from Des Moines to Columbus via Indianapolis, Illinois St (Greyhound Bus Station) and Indianapolis in around 14h 9m.
- Website
- aa.com
Flights from Quad City International Airport to Cleveland-Hopkins International Airport via Chicago O'Hare
- Ave. Duration
- 5h 11m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- $75–460
Flights from Quad City International Airport to Cleveland-Hopkins International Airport via Charlotte
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $130–650
Flights from Quad City International Airport to Cleveland-Hopkins International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 8m
- When
- Every day
- Estimated price
- $180–800
Flights from Des Moines to Detroit via Chicago O'Hare
- Ave. Duration
- 4h 19m
- When
- Monday to Friday
- Estimated price
- $100–600
Flights from Quad City International Airport to John Glenn Columbus International Airport via Charlotte
- Ave. Duration
- 5h
- When
- Thursday
- Estimated price
- $100–550
Flights from Quad City International Airport to John Glenn Columbus International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $140–650
Flights from Quad City International Airport to John Glenn Columbus International Airport via Chicago O'Hare
- Ave. Duration
- 7h 1m
- When
- Every day
- Estimated price
- $65–390
Flights from Quad City International Airport to Dayton via Charlotte
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $170–850
Flights from Quad City International Airport to Dayton via Chicago O'Hare
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $95–600
Flights from Quad City International Airport to Dayton via Dallas/Ft.Worth
- Ave. Duration
- 6h 19m
- When
- Every day
- Estimated price
- $220–1,000
Flights from Quad City International Airport to Covington via Chicago O'Hare
- Ave. Duration
- 4h 40m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Quad City International Airport to Covington via Charlotte
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $160–800
Flights from Quad City International Airport to Covington via Dallas/Ft.Worth
- Ave. Duration
- 7h 29m
- When
- Every day
- Estimated price
- $210–950
- Website
- united.com
Flights from Quad City International Airport to Cleveland-Hopkins International Airport via Chicago O'Hare
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $75–460
Flights from Des Moines to Detroit via Chicago O'Hare
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $100–600
Flights from Quad City International Airport to John Glenn Columbus International Airport via Chicago O'Hare
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $65–390
Flights from Quad City International Airport to Dayton via Chicago O'Hare
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $95–600
Flights from Quad City International Airport to Covington via Chicago O'Hare
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $100–600
- Website
- delta.com
Flights from Quad City International Airport to Cleveland-Hopkins International Airport via Atlanta
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Detroit
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $100–600
Flights from Quad City International Airport to John Glenn Columbus International Airport via Atlanta
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $110–550
Flights from Quad City International Airport to Dayton via Atlanta
- Ave. Duration
- 8h 29m
- When
- Every day
- Estimated price
- $170–850
Flights from Quad City International Airport to Covington via Atlanta
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $160–800
- Website
- allegiantair.com
Flights from Quad City International Airport to Covington via Orlando Sanford
- Ave. Duration
- 6h 7m
- When
- Sunday
- Estimated price
- $240–1,100
Flights from Quad City International Airport to Covington via St. Petersburg
- Ave. Duration
- 7h 41m
- When
- Tuesday and Sunday
- Estimated price
- $250–1,100
- Website
- southwest.com
Flights from Des Moines to Detroit via St. Louis
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- $110–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $24–85
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Toledo
- Ave. Duration
- 3h 59m
- Frequency
- 3 times a day
- Estimated price
- $45–120
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 30m
- Frequency
- Once daily
- Estimated price
- $80–160
- Website
- https://burlingtontrailways.com
- Saver Fares
- $80–120
- Flexible Fares
- $110–160
Bus from Des Moines to Burlington
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $50–80
Bus from Burlington to Galesburg
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
Bus from Des Moines to Chicago
- Ave. Duration
- 7h 15m
- Frequency
- Twice daily
- Estimated price
- $55–160
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–100
- Flexible Fares
- $90–140
- Saver Fare
- $55–110
- Flex Fare
- $75–160
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Indianapolis to Columbus
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $30–75
- Schedules at
- flixbus.com
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Toledo to Columbus - Mound St
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- $13–50
- Website
- https://baronsbus.com
Bus from Chicago to Columbus - Mound St
- Ave. Duration
- 7h 50m
- Frequency
- Twice daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Toledo to Columbus - Mound St
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $27–70
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Columbus
- Ave. Duration
- 4h 40m
- Frequency
- 3 times a day
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Dearborn to Toledo
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
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More Questions & Answers
Yes, the driving distance between Iowa to Ohio is 623 miles. It takes approximately 11h 21m to drive from Iowa to Ohio.
There are 579+ hotels available in Ohio.

















