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How to get fromIowa to Ohioby plane, bus (Flixbus), bus, train, car or bus (Greyhound)

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There are 10 ways to get from Iowa to Ohio by plane, bus (Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Quad City International Airport to Cleveland-Hopkins International Airport

    best
    1. Fly from Quad City International Airport (MLI) to Cleveland-Hopkins International Airport (CLE)planeMLI - CLE
    6h 34m
    $80–465

  2. Fly Quad City International Airport to John Glenn Columbus International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to John Glenn Columbus International Airport (CMH)planeMLI - CMH
    7h 1m
    $69–395

  3. Bus via Indianapolis

    1. Take the bus from Des Moines to Indianapolis Union StationbusDenver
    2. Take the bus from Indianapolis to ColumbusbusFlixBus N2640 / ...
    14h 9m
    $113–230

  4. Bus, train

    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to Galesburgbus
    3. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
    4. Take the train from Chicago Union Station to Toledotrain
    5. Take the bus from Toledo to Columbus - Mound Stbus
    17h 44m
    $148–402

  5. Drive 619.5 mi

    1. Drive from Des Moines to Columbuscar619.5 mi
    11h 21m
    $114–164

  6. Fly Des Moines to Detroit, bus

    1. Fly from Des Moines (DSM) to Detroit (DTW)planeDSM - DTW
    2. Take the bus from Dearborn to Toledobus
    5h 30m

  7. Fly Quad City International Airport to Dayton

    1. Fly from Quad City International Airport (MLI) to Dayton (DAY)planeMLI - DAY
    8h 48m
    $99–604

  8. Fly Quad City International Airport to Covington

    1. Fly from Quad City International Airport (MLI) to Covington (CVG)planeMLI - CVG
    7h 36m
    $105–607

  9. Bus

    1. Take the bus from Des Moines to Indianapolis Union StationbusDenver
    2. Take the bus from Indianapolis Union Station to ColumbusbusGreyhound US0421
    15h 10m
    $113–220

  10. Bus #2

    1. Take the bus from Des Moines to ChicagobusDes Moines
    2. Take the bus from Chicago to Columbus - Mound StbusChicago
    16h 5m
    $86–234

Iowa to Ohio by bus and foot

Calendar7Weekly Services
Duration14h 9mAverage Duration
Ticket$113Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Ohio, USA?

American Airlines, United Airlines, and Delta fly from Quad City International Airport (MLI) to Cleveland-Hopkins International Airport (CLE) every 3 hours. Alternatively, you can take a bus from Des Moines to Columbus via Indianapolis, Illinois St (Greyhound Bus Station) and Indianapolis in around 14h 9m.

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