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How to get fromIowa to Mississippiby plane, bus (Greyhound), bus, train or car

Find Transport to Mississippi

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There are 6 ways to get from Iowa to Mississippi by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Memphis

    best
    1. Fly from Des Moines (DSM) to Memphis (MEM)plane plane DSM - MEM
    4h 28m
    $229–1,147

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Jacksonbus bus
    19h 30m
    $101–320

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the train from Chicago Union Station to Jacksontrain train City of New Orleans
    23h 26m
    $159–345

  4. Drive 803.6 mi

    1. Drive from Des Moines to Jacksoncar car 803.6 mi
    14h 21m
    $147–212

  5. Fly Quad City International Airport to Memphis

    1. Fly from Quad City International Airport (MLI) to Memphis (MEM)plane plane MLI - MEM
    6h 48m
    $123–628

  6. Fly Quad City International Airport to Gulfport-Biloxi Regional Airport

    1. Fly from Quad City International Airport (MLI) to Gulfport-Biloxi Regional Airport (GPT)plane plane MLI - GPT
    7h 1m
    $113–566

Des Moines (DSM) to Memphis (MEM) flights

Calendar89Weekly Planes
Duration5h 37mAverage Duration
Ticket$196Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Mississippi, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Memphis (MEM) hourly. Alternatively, you can take a vehicle from Des Moines to Jackson via Des Moines, Kansas City, and Memphis Bus Station in around 19h 30m.

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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