There are 5 ways to get from Iowa to Madison by bus (Flixbus, Greyhound), car, plane, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Saint Paul
best- Take the bus from Des Moines to St. Paulbus Jefferson Lines 806 / ...
- Take the bus from Saint Paul Union Depot to Madisonbus FlixBus 2548
10h 35m$130–184Drive 274.9 mi
cheapest- Drive from Des Moines to Madisoncar 274.9 mi
5h 6m$51–73Fly from Quad City International Airport, bus
- Fly from Quad City International Airport (MLI) to Chicago O'Hare International Airport (ORD)plane MLI - ORD
- Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus
7h 29m$56–337Bus
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123S / ...
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus Van Galder
11h 56m$84–160Bus to The Eastern Iowa Airport, fly, bus
- Take the bus from Court St Transportation Center to GTC Bay 9bus
- Fly from The Eastern Iowa Airport (CID) to Chicago O'Hare International Airport (ORD)plane CID - ORD
- Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus
8h 38m
Iowa to Madison by bus
Questions & Answers
The cheapest way to get from Iowa to Madison is to drive which costs $50 - $75 and takes 5h 6m.
The fastest way to get from Iowa to Madison is to drive which takes 5h 6m and costs $50 - $75.
No, there is no direct bus from Iowa to Madison. However, there are services departing from Des Moines and arriving at Madison via Saint Paul Union Depot. The journey, including transfers, takes approximately 10h 35m.
The distance between Iowa and Madison is 518 miles. The road distance is 276.5 miles.
The best way to get from Iowa to Madison without a car is to bus via Saint Paul which takes 10h 35m and costs $130 - $190.
It takes approximately 10h 35m to get from Iowa to Madison, including transfers.
Iowa to Madison bus services, operated by Jefferson Lines, depart from Des Moines station.
Iowa to Madison bus services, operated by Jefferson Lines, arrive at St. Paul station.
Yes, the driving distance between Iowa to Madison is 277 miles. It takes approximately 5h 6m to drive from Iowa to Madison.
There are 138+ hotels available in Madison.
What companies run services between Iowa, USA and Madison, WI, USA?
You can take a bus from Des Moines to Madison via Saint Paul Union Depot in around 10h 35m.
- Website
- united.com
Flights from Quad City International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $30–230
Flights from The Eastern Iowa Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $65–470
- Website
- aa.com
Flights from Quad City International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- $30–230
Flights from The Eastern Iowa Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $65–470
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to St. Paul
- Ave. Duration
- 4h 40m
- Frequency
- Twice daily
- Estimated price
- $60–90
- Book at
- Jefferson Lines
- Adult
- $60–90
Bus from Saint Paul Union Depot to Madison
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- $65–95
- Book at
- Jefferson Lines
- Adult
- $65–95
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Saint Paul Union Depot to Madison
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $40–70
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Saint Paul Union Depot to Madison
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–95
- Website
- Greyhound
- Phone
- +1 (866) 912 - 6224
- questions@coachusa.com
- Website
- Rockland Coaches
Bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 2h 50m
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 50m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
Bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 2h 50m
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
- Phone
- +1-319-362-0375
- Website
- 380 Express Corridor Rides
Bus from Court St Transportation Center to GTC Bay 9
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Website
- 380 Express Corridor Rides
- Schedules at
- 380 Express Schedule
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