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How to get fromIowa to Jacksonvilleby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to Jacksonville

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There are 6 ways to get from Iowa to Jacksonville by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Jacksonville (JAX)plane plane DSM - JAX
    4h 13m
    $209–974
  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Jacksonville (JAX)plane plane MLI - JAX
    8h 19m
    $113–605
  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    26h 55m
    $194–460
  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Jacksonvilletrain train Floridian
    44h 1m
    $505–1,073
  5. Drive 1,177.5 mi

    1. Drive from Des Moines to Jacksonvillecar car 1,177.5 mi
    22h 14m
    $215–311
  6. Bus, train via Bloomington

    1. Take the bus from Des Moines to Bloomington-Normalbus bus
    2. Take the train from Bloomington-Normal to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Jacksonvilletrain train
    46h 21m
    $530–1,138

Des Moines (DSM) to Jacksonville (JAX) flights

Calendar67Weekly Planes
Duration4h 57mAverage Duration
Ticket$191Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Jacksonville, FL, USA?

Allegiant Air, Southwest Airlines, and three other airlines fly from Des Moines (DSM) to Jacksonville (JAX) every 3 hours. Alternatively, you can take a vehicle from Des Moines to Jacksonville via Des Moines, St Louis Bus Station, and Atlanta Bus Station in around 26h 55m.

Airlines
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