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How to get fromIowa to Jacksonvilleby plane, bus (Greyhound, Flixbus), bus, train or car

Find Transport to Jacksonville

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There are 6 ways to get from Iowa to Jacksonville by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Jacksonville (JAX)plane plane DSM - JAX
    4h 14m
    $209–1,024

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Jacksonville (JAX)plane plane MLI - JAX
    8h 37m
    $103–555

  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    30h 10m
    $164–430

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the train from Chicago Union Station to Jacksonvilletrain train Floridian
    43h 54m
    $250–713

  5. Drive 1,188.7 mi

    1. Drive from Des Moines to Jacksonvillecar car 1,188.7 mi
    21h 47m
    $217–314

  6. Fly from Waterloo Municipal Airport

    1. Fly from Waterloo Municipal Airport (ALO) to Jacksonville (JAX)plane plane ALO - JAX
    6h 40m
    $140–625

Des Moines (DSM) to Jacksonville (JAX) flights

Calendar61Weekly Planes
Duration4h 56mAverage Duration
Ticket$197Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Jacksonville, FL, USA?

Allegiant Air, Delta, and three other airlines fly from Des Moines (DSM) to Jacksonville (JAX) every 3 hours. Alternatively, you can take a vehicle from Des Moines to Jacksonville via Des Moines, Chicago Bus Station, and Atlanta Bus Station in around 30h 10m.

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Need to know: Greyhound

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