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How to get fromIowa to Ithacaby plane, bus, train, bus (Greyhound, Flixbus) or car

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There are 11 ways to get from Iowa to Ithaca by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Syracuse Hancock International Airport, bus

    best
    1. Fly from Des Moines (DSM) to Syracuse Hancock International Airport (SYR)planeDSM - SYR
    2. Take the bus from Syracuse Airport, NY to Ithaca, NYbus
    7h 14m
    $228–1,176

  2. Fly Quad City International Airport to Syracuse Hancock International Airport, bus

    cheapest
    1. Fly from Quad City International Airport (MLI) to Syracuse Hancock International Airport (SYR)planeMLI - SYR
    2. Take the bus from Syracuse Airport, NY to Ithaca, NYbus
    9h 2m
    $142–757

  3. Bus, train

    1. Take the bus from Des Moines to Chicagobus
    2. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain
    3. Take the bus from Syracuse Bus Station to Ithacabus
    23h 26m
    $145–384

  4. Bus via Cleveland

    1. Take the bus from Des Moines to Chicagobus
    2. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus
    4. Take the bus from Buffalo to Ithacabus
    24h 33m
    $145–367

  5. Drive 974 mi

    1. Drive from Des Moines to Ithacacar974 mi
    16h 47m
    $178–257

  6. Fly Des Moines to Greater Binghamton Airport, bus

    1. Fly from Des Moines (DSM) to Greater Binghamton Airport (BGM)planeDSM - BGM
    2. Take the bus from Binghamton to Ithacabus
    8h 59m
    $176–701

  7. Fly Des Moines to Elmira/Corning Regional Airport, bus

    1. Fly from Des Moines (DSM) to Elmira/Corning Regional Airport (ELM)planeDSM - ELM
    2. Take the bus from Transit Center - PO Side to Tompkins County Librarybus
    7h 45m

  8. Fly The Eastern Iowa Airport to Syracuse Hancock International Airport, bus

    1. Fly from The Eastern Iowa Airport (CID) to Syracuse Hancock International Airport (SYR)planeCID - SYR
    2. Take the bus from Syracuse Airport, NY to Ithaca, NYbus
    8h 41m
    $192–995

  9. Bus, train via 7Th St / Locust St, Dsm

    1. Take the bus from Des Moines to Chicagobus
    2. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain
    3. Take the bus from Syracuse Bus Station to Ithacabus
    23h 39m
    $156–382

  10. Bus, train via Galesburg

    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to Galesburgbus
    3. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
    4. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain
    5. Take the bus from Syracuse Bus Station to Ithacabus
    24h 57m
    $175–422

  11. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus
    2. Take the bus from Chicago Bus Station to Detroit Bus Stationbus
    3. Take the bus from Detroit Bus Station to Torontobus
    4. Take the bus from Toronto to Ithacabus
    31h
    $159–330

Iowa to Ithaca by bus, foot, and train

Calendar10Weekly Services
Duration23h 26mAverage Duration
Ticket$145Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Ithaca, NY, USA?

You can take a bus from Pennsylvania Ave / E University Ave to Ithaca via 7Th St / Locust St, Dsm, Des Moines, Chicago Bus Station, Cleveland Bus Station, Cleveland, OH, Buffalo, NY, and Buffalo in around 24h 33m.

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