Rome2Rio

How to get fromIowa to Ithacaby plane, bus, train, bus (Greyhound, Flixbus) or car

Find Transport to Ithaca

See all options

There are 7 ways to get from Iowa to Ithaca by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Syracuse Hancock International Airport, bus

    best
    1. Fly from Des Moines (DSM) to Syracuse Hancock International Airport (SYR)plane plane DSM - SYR
    2. Take the bus from Syracuse Airport, NY to Ithaca, NYbus bus
    7h 18m
    $288–1,376

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    4. Take the bus from Buffalo to Ithacabus bus
    24h 15m
    $132–335

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Rochestertrain train
    3. Take the bus from Rochester to Ithacabus bus 231
    22h 39m
    $134–365

  4. Drive 974 mi

    1. Drive from Des Moines to Ithacacar car 974 mi
    16h 54m
    $178–257

  5. Fly Des Moines to Greater Binghamton Airport, bus

    1. Fly from Des Moines (DSM) to Greater Binghamton Airport (BGM)plane plane DSM - BGM
    2. Take the bus from Binghamton to Ithacabus bus
    9h 6m
    $207–851

  6. Fly Des Moines to Elmira/Corning Regional Airport, bus

    1. Fly from Des Moines (DSM) to Elmira/Corning Regional Airport (ELM)plane plane DSM - ELM
    2. Take the bus from Transit Center - PO Side to Tompkins County Librarybus bus
    8h 18m

  7. Fly Quad City International Airport to Syracuse Hancock International Airport, bus

    1. Fly from Quad City International Airport (MLI) to Syracuse Hancock International Airport (SYR)plane plane MLI - SYR
    2. Take the bus from Syracuse Airport, NY to Ithaca, NYbus bus
    8h 55m
    $152–807

Des Moines (DSM) to Syracuse Hancock International Airport (SYR) flights

Calendar67Weekly Planes
Duration6h 30mAverage Duration
Ticket$256Cheapest Price
See schedules

Questions & Answers

What companies run services between Iowa, USA and Ithaca, NY, USA?

You can take a vehicle from Des Moines to Ithaca via Des Moines, Chicago Bus Station, Cleveland Bus Station, Cleveland, OH, Buffalo, NY, and Buffalo in around 24h 15m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Iowa

Trips to Ithaca

Popular routes