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How to get fromIowa to Gainesvilleby plane, bus (Flixbus), bus, train, car or bus (Greyhound)

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There are 10 ways to get from Iowa to Gainesville by plane, bus (Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Gainesville Regional Airport

    best
    1. Fly from Des Moines (DSM) to Gainesville Regional Airport (GNV)planeDSM - GNV
    6h 17m
    $250–1,223
  2. Fly Quad City International Airport to Gainesville Regional Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Gainesville Regional Airport (GNV)planeMLI - GNV
    8h 4m
    $134–654
  3. Bus

    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to St Louisbus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
    4. Take the bus from Atlanta - Civic Center MARTA Station to Gainesvillebus
    26h 34m
    $179–455
  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus
    2. Take the train from Chicago Union Station to Jacksonvilletrain
    3. Take the bus from Jacksonville to Gainesvillebus
    46h 33m
    $304–1,182
  5. Drive 1,209.1 mi

    1. Drive from Des Moines to Gainesvillecar1,209.1 mi
    21h 2m
    $221–319
  6. Fly The Eastern Iowa Airport to Gainesville Regional Airport

    1. Fly from The Eastern Iowa Airport (CID) to Gainesville Regional Airport (GNV)planeCID - GNV
    7h 29m
    $154–742
  7. Fly Des Moines to Orlando Sanford, drive

    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)planeDSM - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Gainesvillecar
    5h 24m
    $198–801
  8. Fly Omaha to Gainesville Regional Airport

    1. Fly from Omaha (OMA) to Gainesville Regional Airport (GNV)planeOMA - GNV
    8h 43m
    $255–1,205
  9. Bus via Champaign

    1. Take the bus from Des Moines to Champaignbus
    2. Take the bus from Champaign Intermodal Trans Ctr to Atlanta Bus Stationbus
    3. Take the bus from Atlanta Bus Station to Gainesvillebus
    29h 25m
    $206–388
  10. Bus #2 (Greyhound)

    1. Take the bus from Des Moines to Chicago Bus Stationbus
    2. Take the bus from Chicago Train Station to Atlanta Bus Stationbus
    3. Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus
    32h 10m
    $191–402

Iowa to Gainesville by bus and subway

Calendar7Weekly Services
Duration26h 34mAverage Duration
Ticket$179Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Gainesville, FL, USA?

Delta and American Airlines fly from Des Moines (DSM) to Gainesville Regional Airport (GNV) 5 times a day. Alternatively, you can take a bus from Des Moines to Gainesville via Burlington, St Louis Bus Station, Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta - Civic Center MARTA Station in around 26h 34m.

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