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How to get fromIowa to Gainesvilleby plane, bus (Greyhound, Flixbus), bus, train or car

Find Transport to Gainesville

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There are 7 ways to get from Iowa to Gainesville by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Gainesville Regional Airport (GNV)plane plane DSM - GNV
    7h 16m
    $170–823
  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Gainesville Regional Airport (GNV)plane plane MLI - GNV
    7h 52m
    $84–424
  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    29h 10m
    $159–365
  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Gainesvillebus bus
    46h 29m
    $246–726
  5. Drive 1,209.1 mi

    1. Drive from Des Moines to Gainesvillecar car 1,209.1 mi
    21h 12m
    $221–319
  6. Fly from Omaha

    1. Fly from Omaha (OMA) to Gainesville Regional Airport (GNV)plane plane OMA - GNV
    9h 24m
    $155–805
  7. Bus, train via Atlanta

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to Warrensburg Chamber Of Commercebus bus
    3. Take the train from Warrensburg Amtrak Station to St. Louistrain train
    4. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    5. Take the bus from Atlanta - Civic Center MARTA Station to Gainesvillebus bus
    29h 15m
    $171–488

Des Moines (DSM) to Gainesville Regional Airport (GNV) flights

Calendar38Weekly Planes
Duration7h 25mAverage Duration
Ticket$151Cheapest Price
See schedules

Questions & Answers

What companies run services between Iowa, USA and Gainesville, FL, USA?

Delta and American Airlines fly from Des Moines (DSM) to Gainesville Regional Airport (GNV) 5 times a day. Alternatively, you can take a vehicle from Des Moines to Gainesville via Des Moines, Chicago Bus Station, and Atlanta Bus Station in around 29h 10m.

Airlines
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Bus operators

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