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How to get fromIowa to Gainesvilleby plane, bus (Flixbus), bus, train, car, or bus (Greyhound)

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There are 10 ways to get from Iowa to Gainesville by plane, bus (Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Gainesville Regional Airport

    best
    1. Fly from Des Moines (DSM) to Gainesville Regional Airport (GNV)plane plane DSM - GNV
    5h 54m
    $170–773

  2. Fly Quad City International Airport to Gainesville Regional Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Gainesville Regional Airport (GNV)plane plane MLI - GNV
    8h 57m
    $94–434

  3. Bus via Indianapolis

    1. Take the bus from Des Moines to Indianapolisbus bus
    2. Take the bus from Indianapolis to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    26h 49m
    $308–438

  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Gainesvillebus bus
    45h 36m
    $598–1,239

  5. Drive 1,198 mi

    1. Drive from Des Moines to Gainesvillecar car 1,198 mi
    21h 40m
    $219–316

  6. Fly Des Moines to Orlando Sanford, drive

    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Gainesvillecar car
    5h 26m
    $198–801

  7. Fly Omaha to Gainesville Regional Airport

    1. Fly from Omaha (OMA) to Gainesville Regional Airport (GNV)plane plane OMA - GNV
    8h 20m
    $125–605

  8. Bus to The Eastern Iowa Airport, fly to Gainesville Regional Airport

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Gainesville Regional Airport (GNV)plane plane CID - GNV
    10h

  9. Bus

    1. Take the bus from Des Moines to Champaignbus bus
    2. Take the bus from Champaign Intermodal Trans Ctr to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    28h 40m
    $323–464

  10. Bus via North Walmart Supercenter

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus bus
    30h 8m
    $256–432

Iowa to Gainesville by bus and foot

Calendar7Weekly Services
Duration26h 49mAverage Duration
Ticket$308Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Gainesville.ExpandLaunch map view
  • Distance: 1,050.3 mi
  • Duration: 5h 54m

What companies run services between Iowa, USA and Gainesville, FL, USA?

Delta and American Airlines fly from Des Moines (DSM) to Gainesville Regional Airport (GNV) every 4 hours. Alternatively, you can take a bus from Des Moines to Gainesville via Indianapolis, Indianapolis, and Atlanta Bus Station in around 26h 49m.

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