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How to get fromIowa to Durhamby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 8 ways to get from Iowa to Durham by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Raleigh-Durham International Airport

    best
    1. Fly from Des Moines (DSM) to Raleigh-Durham International Airport (RDU)plane plane DSM - RDU
    5h 54m
    $164–727

  2. Fly Quad City International Airport to Raleigh-Durham International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Raleigh-Durham International Airport (RDU)plane plane MLI - RDU
    8h 15m
    $93–448

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Durhambus bus
    29h 10m
    $204–400

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Carytrain train Floridian
    34h 33m
    $415–811

  5. Drive 1,053.4 mi

    1. Drive from Des Moines to Durhamcar car 1,053.4 mi
    18h 17m
    $193–278

  6. Fly Omaha to Raleigh-Durham International Airport

    1. Fly from Omaha (OMA) to Raleigh-Durham International Airport (RDU)plane plane OMA - RDU
    8h 27m
    $139–659

  7. Fly Des Moines to Charlotte Douglas International Airport, train

    1. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane plane DSM - CLT
    2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train
    7h 20m
    $247–1,022

  8. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Durham Amtrak Stationtrain train
    35h 1m
    $447–897

Des Moines (DSM) to Raleigh-Durham International Airport (RDU) flights

Calendar124Weekly Planes
Duration4h 58mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Durham.ExpandLaunch map view
  • Distance: 913.5 mi
  • Duration: 5h 54m

What companies run services between Iowa, USA and Durham, NC, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Raleigh-Durham International Airport (RDU) hourly. Alternatively, you can take a vehicle from Des Moines to Durham via Des Moines, St Louis Bus Station, and Atlanta Bus Station in around 29h 10m.

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