There are 6 ways to get from Iowa to Durham by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines
best- Fly from Des Moines (DSM) to Raleigh-Durham International Airport (RDU)plane DSM - RDU
5h 25m$145–629Fly from Quad City International Airport
cheapest- Fly from Quad City International Airport (MLI) to Raleigh-Durham International Airport (RDU)plane MLI - RDU
7h 59m$108–608Bus
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Durhambus
29h 20m$248–412Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0155S / ...
- Take the train from Chicago Union Station to Raleigh Union Stationtrain Floridian
34h 58m$621–1,008Drive 1,053.4 mi
- Drive from Des Moines to Durhamcar 1,053.4 mi
18h 17m$180–261Bus, train via Galesburg
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Raleigh Union Stationtrain
- Take the train from Raleigh Union Station to Durham Amtrak Stationtrain
35h 1m$692–1,132
Iowa to Durham by bus
Comparing Your Travel Options
The cheapest way to get from Iowa to Durham is to drive which costs $180 - $260 and takes 18h 17m.
The fastest way to get from Iowa to Durham is to fly which takes 5h 25m and costs $140 - $650.
No, there is no direct bus from Iowa to Durham. However, there are services departing from Des Moines and arriving at Durham via Kansas City Bus Station, St Louis Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 29h 20m.
The distance between Iowa and Durham is 919 miles. The road distance is 1059.5 miles.
The best way to get from Iowa to Durham without a car is to bus which takes 29h 20m and costs $240 - $420.
It takes approximately 5h 25m to get from Iowa to Durham, including transfers.
Iowa to Durham bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Iowa to Durham is to fly which takes 5h 25m and costs $140 - $650. Alternatively, you can bus, which costs $240 - $420 and takes 29h 20m.
Iowa to Durham bus services, operated by Jefferson Lines, arrive at Kansas City station.
Durham is 1h ahead of Iowa. It is currently 7:36 AM in Iowa and 8:36 AM in Durham.
What companies run services between Iowa, USA and Durham, NC, USA?
Southwest Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Raleigh-Durham International Airport (RDU) hourly. Alternatively, you can take a bus from Des Moines to Durham via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Atlanta Bus Station in around 29h 20m.
- Website
- aa.com
Flights from Des Moines to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $120–600
Flights from Des Moines to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 5h 17m
- When
- Sunday
- Estimated price
- $130–650
Flights from Des Moines to Raleigh-Durham International Airport via Chicago O'Hare
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $120–600
Flights from Quad City International Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $100–600
Flights from Quad City International Airport to Raleigh-Durham International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 11m
- When
- Every day
- Estimated price
- $180–800
Flights from Quad City International Airport to Raleigh-Durham International Airport via Chicago O'Hare
- Ave. Duration
- 6h 43m
- When
- Every day
- Estimated price
- $100–600
- Website
- delta.com
Flights from Des Moines to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Raleigh-Durham International Airport via Minneapolis
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $140–700
Flights from Quad City International Airport to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $120–650
- Website
- united.com
Flights from Des Moines to Raleigh-Durham International Airport via Chicago O'Hare
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $120–600
Flights from Quad City International Airport to Raleigh-Durham International Airport via Chicago O'Hare
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $100–600
- Website
- southwest.com
Flights from Des Moines to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 45m
- When
- Tuesday and Wednesday
- Estimated price
- $120–600
Flights from Des Moines to Raleigh-Durham International Airport via Chicago Midway
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $120–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 24h 1m
- Frequency
- Once daily
- Estimated price
- $550–900
- Website
- Amtrak
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 24h 1m
- Frequency
- Once daily
- Estimated price
- $550–900
- Website
- Amtrak
Train from Raleigh Union Station to Durham Amtrak Station
- Ave. Duration
- 30 min
- Frequency
- 5 times a day
- Estimated price
- $14–22
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- Every 4 hours
- Estimated price
- $45–70
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Twice daily
- Estimated price
- $100–160
- Website
- Greyhound
Bus from Atlanta Bus Station to Durham
- Ave. Duration
- 8h 20m
- Frequency
- Twice daily
- Estimated price
- $70–110
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- Once daily
- Estimated price
- $90–140
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Durham
- Ave. Duration
- 7h 10m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Iowa to Durham is 1060 miles. It takes approximately 18h 17m to drive from Iowa to Durham.
There are 404+ hotels available in Durham.









