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How to get fromIowa to Clevelandby plane, bus, train, car, bus (Greyhound), or bus (Greyhound, Flixbus)

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There are 7 ways to get from Iowa to Cleveland by plane, bus, train, car, bus (Greyhound), or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE)plane plane DSM - CLE
    4h 27m
    $171–874

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Cleveland-Hopkins International Airport (CLE)plane plane MLI - CLE
    6h 32m
    $95–555

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Cleveland Amtraktrain train Floridian / ...
    14h 24m
    $159–325

  4. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Cleveland Amtraktrain train
    15h 35m
    $189–400

  5. Drive 658.9 mi

    1. Drive from Des Moines to Clevelandcar car 658.9 mi
    10h 58m
    $121–174

  6. Bus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis, IN to Toledobus bus
    3. Take the bus from Toledo to Clevelandbus bus
    17h 25m
    $106–245

  7. Bus via Chicago

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Robert K Pfaff Transit Center - Akronbus bus
    3. Take the bus from Robert K Pfaff Transit Center - Akron to W. Prospect Ave & Superior Avebus bus 61
    17h 41m
    $111–197

Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) flights

Calendar126Weekly Planes
Duration5h 26mAverage Duration
Ticket$149Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Cleveland.ExpandLaunch map view
  • Distance: 629.3 mi
  • Duration: 4h 27m

What companies run services between Iowa, USA and Cleveland, OH, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a vehicle from Des Moines to Cleveland via Des Moines, Indianapolis, IN, and Toledo in around 17h 25m.

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