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How to get fromIowa to Clevelandby plane, bus, train, car, bus (Greyhound), or bus (Greyhound, Amtrak)

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There are 8 ways to get from Iowa to Cleveland by plane, bus, train, car, bus (Greyhound), or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE)plane plane DSM - CLE
    4h 22m
    $191–1,024

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago to Clevelandbus bus Chicago
    15h 5m
    $84–190

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Cleveland Amtraktrain train Floridian / ...
    14h 24m
    $149–320

  4. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Cleveland Amtraktrain train
    15h 50m
    $179–380

  5. Drive 658.9 mi

    1. Drive from Des Moines to Clevelandcar car 658.9 mi
    10h 58m
    $121–174

  6. Fly from Quad City International Airport

    1. Fly from Quad City International Airport (MLI) to Cleveland-Hopkins International Airport (CLE)plane plane MLI - CLE
    6h 32m
    $100–605

  7. Fly from Omaha

    1. Fly from Omaha (OMA) to Cleveland-Hopkins International Airport (CLE)plane plane OMA - CLE
    6h 55m
    $186–956

  8. Bus via Toledo

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Union Station to Toledobus bus
    3. Take the bus from Toledo Bus Stop to Cleveland Bus Stationbus bus
    15h 43m
    $152–273

Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) flights

Calendar134Weekly Planes
Duration5h 47mAverage Duration
Ticket$178Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Cleveland.ExpandLaunch map view
  • Distance: 629.3 mi
  • Duration: 4h 22m

What companies run services between Iowa, USA and Cleveland, OH, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a vehicle from Des Moines to Cleveland via Des Moines and Chicago in around 15h 5m.

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