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How to get fromIowa to Clevelandby plane, bus, train, car, or bus (Greyhound)

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There are 7 ways to get from Iowa to Cleveland by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE)plane plane DSM - CLE
    4h 22m
    $181–974
  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Cleveland-Hopkins International Airport (CLE)plane plane MLI - CLE
    6h 37m
    $95–555
  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Cleveland Amtraktrain train Floridian / ...
    14h 24m
    $159–330
  4. Drive 658.9 mi

    1. Drive from Des Moines to Clevelandcar car 658.9 mi
    10h 58m
    $121–174
  5. Fly from Omaha

    1. Fly from Omaha (OMA) to Cleveland-Hopkins International Airport (CLE)plane plane OMA - CLE
    6h 55m
    $186–1,006
  6. Bus, train via Toledo

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Union Station to Toledobus bus
    3. Take the train from Toledo to Cleveland Amtraktrain train
    15h 13m
    $174–315
  7. Bus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis, IN to Toledobus bus
    3. Take the bus from Toledo to Clevelandbus bus
    17h 25m
    $116–265

Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) flights

Calendar121Weekly Planes
Duration5h 18mAverage Duration
Ticket$162Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Cleveland, OH, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a vehicle from Des Moines to Cleveland via Des Moines, Indianapolis, IN, and Toledo in around 17h 25m.

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Need to know: Greyhound

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