There are 5 ways to get from Iowa to Chicago by plane, bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines
best- Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane DSM - ORD
2h 32m$80–446Line 60 bus to Quad City International Airport, fly
cheapest- Take the bus from District to SouthPark Mall Shelterbus
- Fly from Quad City International Airport (MLI) to Chicago O'Hare International Airport (ORD)plane MLI - ORD
4h 13m$34–227Bus (Greyhound)
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
7h 10m$49–110Drive 330.7 mi
- Drive from Des Moines to Chicagocar 330.7 mi
5h 33m$61–88Fly from Waterloo Municipal Airport
- Fly from Waterloo Municipal Airport (ALO) to Chicago O'Hare International Airport (ORD)plane ALO - ORD
2h 21m$56–267
Des Moines (DSM) to Chicago O'Hare International Airport (ORD) flights
Questions & Answers
The cheapest way to get from Iowa to Chicago is to drive which costs $60 - $90 and takes 5h 33m.
The fastest way to get from Iowa to Chicago is to fly which takes 2h 21m and costs $55 - $270.
The distance between Iowa and Chicago is 324 miles. The road distance is 332.7 miles.
The best way to get from Iowa to Chicago without a car is to bus which takes 7h 10m and costs $45 - $110.
It takes approximately 2h 32m to get from Iowa to Chicago, including transfers.
The best way to get from Iowa to Chicago is to fly which takes 2h 32m and costs $75 - $450. Alternatively, you can bus, which costs $45 - $110 and takes 7h 10m.
Yes, the driving distance between Iowa to Chicago is 333 miles. It takes approximately 5h 33m to drive from Iowa to Chicago.
There are 1068+ hotels available in Chicago.
What companies run services between Iowa, USA and Chicago, IL, USA?
American Airlines and United Airlines fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD) every 4 hours. Alternatively, Greyhound USA operates a bus from Des Moines to Chicago Bus Station 3 times a day. Tickets cost $40–100 and the journey takes 7h 5m.
- Website
- aa.com
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $60–420
Flights from Waterloo Municipal Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $35–240
Flights from Quad City International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $30–220
- Website
- united.com
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $60–420
Flights from Quad City International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $30–220
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $40–100
- Website
- https://www.greyhound.com/
- Phone
- +1 309-788-3360
- Website
- metroqc.com
Bus from District to SouthPark Mall Shelter
- Ave. Duration
- 38 min
- Frequency
- Hourly
- Estimated price
- $1
- Website
- https://www.metroqc.com
- Adult Cash Fare
- $1
Want to know more about travelling around United States
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