Rome2Rio

How to get fromIowa to Cheyenneby plane, bus (Greyhound), car or bus

Find Transport to Cheyenne

See all options

There are 7 ways to get from Iowa to Cheyenne by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Cheyenne Airport

    best
    1. Fly from Des Moines (DSM) to Cheyenne Airport (CYS)planeDSM - CYS
    5h 27m
    $131–637

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Omahabus
    2. Take the bus from Omaha, NE to Denver Union Stationbus
    3. Take the bus from Denver Union Station to Cheyennebus
    17h 30m
    $107–205

  3. Drive 627.6 mi

    1. Drive from Des Moines to Cheyennecar627.6 mi
    9h 39m
    $115–166

  4. Fly Des Moines to Denver, bus

    1. Fly from Des Moines (DSM) to Denver (DEN)planeDSM - DEN
    2. Take the bus from Denver International Airport Pickups to Warren AFBbus
    5h 35m
    $198–861

  5. Fly Omaha to Cheyenne Airport

    1. Fly from Omaha (OMA) to Cheyenne Airport (CYS)planeOMA - CYS
    6h 23m
    $111–569

  6. Bus via Denver Airport (DEN)

    1. Take the bus from Des Moines to Omahabus
    2. Take the bus from Omaha, NE to Denverbus
    3. Take the bus from Denver International Airport Pickups to Warren AFBbus
    17h 46m
    $227–330

  7. Bus #2

    1. Take the bus from Des Moines to DenverbusIndianapolis
    2. Take the bus from Denver International Airport Pickups to Warren AFBbusGroome Transportation - Wyoming
    17h 54m
    $173–320

Iowa to Cheyenne by bus

Calendar7Weekly Buses
Duration17h 30mAverage Duration
Ticket$107Cheapest Price
See schedules

Questions & Answers

What companies run services between Iowa, USA and Cheyenne, WY, USA?

United Airlines and Southwest Airlines fly from Des Moines (DSM) to Cheyenne Airport (CYS) 4 times a day. Alternatively, you can take a bus from Des Moines to Cheyenne Regional Medical Center via Omaha, NE, Denver Union Station, and Greyhound in around 17h 30m.

Transport is disrupted due to the Russia-Ukraine war. Read more

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Iowa

Trips to Cheyenne

Popular routes