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How to get fromIowa to Bryson Cityby plane, car, bus or train

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There are 7 ways to get from Iowa to Bryson City by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines, drive

    best
    1. Fly from Des Moines (DSM) to Mcghee Tyson Airport (TYS)plane plane DSM - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Bryson Citycar car
    6h 44m
    $312–1,643
  2. Fly from Quad City International Airport, drive

    cheapest
    1. Fly from Quad City International Airport (MLI) to Mcghee Tyson Airport (TYS)plane plane MLI - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Bryson Citycar car
    8h 18m
    $146–774
  3. Bus, drive

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Toledo Bus Stopbus bus
    3. Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from Asheville, NC to Bryson Citycar car
    31h 52m
    $165–323
  4. Bus, train, drive

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Bryson Citycar car
    40h 43m
    $240–546
  5. Drive 891.2 mi

    1. Drive from Des Moines to Bryson Citycar car 891.2 mi
    16h 4m
    $163–235
  6. Fly from Omaha, drive

    1. Fly from Omaha (OMA) to Mcghee Tyson Airport (TYS)plane plane OMA - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Bryson Citycar car
    9h 12m
    $307–1,625
  7. Bus, drive via Hurricane

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Mound St to Hurricanebus bus
    4. Take the bus from Hurricane to Charlotte Bus Stationbus bus
    5. Take the bus from Charlotte Bus Station to Asheville, NCbus bus
    6. Drive from New Leicester Hwy at Walgreens to Bryson Citycar car
    34h 1m
    $151–367

Des Moines (DSM) to Mcghee Tyson Airport (TYS) flights

Calendar83Weekly Planes
Duration5h 22mAverage Duration
Ticket$284Cheapest Price
See schedules

Questions & Answers

What companies run services between Iowa, USA and Bryson City, NC, USA?

There is no direct connection from Iowa to Bryson City. However, you can take the taxi to Des-Moines-Airport-DSM airport, fly to Mcghee Tyson Airport (TYS), then drive to Bryson City. Alternatively, you can take a vehicle from Des Moines to Bryson City via Des Moines, Chicago Bus Station, Toledo Bus Stop, Winston Salem(Trans Center), and Asheville, NC in around 31h 52m.

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