There are 7 ways to get from Iowa to Appleton by plane, bus (Amtrak), car, bus (Greyhound, Flixbus), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines
best- Fly from Des Moines (DSM) to Appleton International Airport (ATW)plane DSM - ATW
3h 58m$122–594Fly from Quad City International Airport
cheapest- Fly from Quad City International Airport (MLI) to Appleton International Airport (ATW)plane MLI - ATW
5h 42m$61–315Bus via Saint Paul
- Take the bus from Des Moines to St. Paulbus
- Take the bus from St. Paul-Minneapolis to Wausau Amtrak Bus Stopbus
- Take the bus from Wausau Transit Center to Appletonbus
13h 35m$115–246Drive 380.2 mi
- Drive from Des Moines to Appletoncar 380.2 mi
7h 4m$70–101Bus
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0155S
- Take the bus from Chicago Bus Station to Appleton Transit Centerbus FlixBus 2550
13h 40m$92–165Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee to Appleton Amtrak Stationbus
14h 12m$103–225Bus, train via Saint Paul
- Take the bus from Des Moines to St. Paulbus
- Take the train from St. Paul-Minneapolis to Milwaukeetrain
- Take the bus from Milwaukee to Appleton Amtrak Stationbus
15h 9m$129–365
Des Moines (DSM) to Appleton International Airport (ATW) flights
Questions & Answers
The cheapest way to get from Iowa to Appleton is to drive which costs $65 - $100 and takes 7h 4m.
The fastest way to get from Iowa to Appleton is to fly which takes 3h 58m and costs $120 - $600.
The distance between Iowa and Appleton is 335 miles. The road distance is 382.4 miles.
The best way to get from Iowa to Appleton without a car is to bus via Saint Paul which takes 13h 35m and costs $110 - $250.
It takes approximately 3h 58m to get from Iowa to Appleton, including transfers.
The best way to get from Iowa to Appleton is to fly which takes 3h 58m and costs $120 - $600. Alternatively, you can bus via Saint Paul, which costs $110 - $250 and takes 13h 35m.
Yes, the driving distance between Iowa to Appleton is 382 miles. It takes approximately 7h 4m to drive from Iowa to Appleton.
There are 71+ hotels available in Appleton.
What companies run services between Iowa, USA and Appleton, WI, USA?
American Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to Appleton International Airport (ATW) hourly. Alternatively, you can take a vehicle from Des Moines to Appleton via Des Moines, St. Paul, St. Paul-Minneapolis, Wausau Amtrak Bus Stop, and Wausau Transit Center in around 13h 35m.
- Website
- aa.com
Flights from Des Moines to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $85–550
Flights from Des Moines to Appleton International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $190–900
Flights from Des Moines to Appleton International Airport via Charlotte
- Ave. Duration
- 7h 29m
- When
- Tuesday
- Estimated price
- $190–900
Flights from Quad City International Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $40–290
Flights from Quad City International Airport to Appleton International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $120–600
- Website
- united.com
Flights from Des Moines to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $85–550
Flights from Des Moines to Appleton International Airport via Denver
- Ave. Duration
- 7h 33m
- When
- Every day
- Estimated price
- $180–900
Flights from Quad City International Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- $40–290
- Website
- delta.com
Flights from Des Moines to Appleton International Airport via Detroit
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to Appleton International Airport via Minneapolis
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $85–550
Flights from Des Moines to Appleton International Airport via Atlanta
- Ave. Duration
- 6h 42m
- When
- Saturday
- Estimated price
- $180–900
Flights from Quad City International Airport to Appleton International Airport via Atlanta
- Ave. Duration
- 6h 17m
- When
- Saturday
- Estimated price
- $110–550
- Website
- allegiantair.com
Flights from Des Moines to Appleton International Airport via Nashville
- Ave. Duration
- 4h 19m
- When
- Monday and Friday
- Estimated price
- $140–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–50
- Website
- https://www.amtrak.com/home.html
Train from St. Paul-Minneapolis to Milwaukee
- Ave. Duration
- 5h 50m
- Frequency
- 3 times a day
- Estimated price
- $85–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to St. Paul
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $23–110
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from St. Paul-Minneapolis to Wausau Amtrak Bus Stop
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $60–100
- Website
- https://www.amtrak.com/home.html
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 24m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Website
- https://www.amtrak.com/home.html
- Phone
- 920 496 3600
- Website
- golamers.com
Bus from Wausau Transit Center to Appleton
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $23–26
- Schedules at
- golamers.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $23–26
- Schedules at
- golamers.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $60–110
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Appleton Transit Center
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $23–45
- Schedules at
- flixbus.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a week
- Estimated price
- $12–22
- Schedules at
- flixbus.com
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