There are 6 ways to get from Iowa to Appleton by plane, bus, car, bus (Greyhound), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines
best- Fly from Des Moines (DSM) to Appleton International Airport (ATW)plane DSM - ATW
3h 58m$107–489Fly from Quad City International Airport
cheapest- Fly from Quad City International Airport (MLI) to Appleton International Airport (ATW)plane MLI - ATW
6h 59m$61–340Bus via La Crosse
- Take the bus from Des Moines to Owatonnabus
- Take the bus from Owatonna to Rochesterbus
- Take the bus from Rochester to La Crossebus
- Take the bus from La Crosse Grand River Station to Appleton Valley Transitbus
14h 5m$119–190Drive 380.3 mi
- Drive from Des Moines to Appletoncar 380.3 mi
7h 7m$70–101Bus
- Take the bus from Des Moines to Minneapolisbus
- Take the bus from Minneapolis Bus Station to Wausau Transit Centerbus
- Take the bus from Wausau Transit to Appletonbus
14h 15m$117–166Bus, train
- Take the bus from Des Moines to St. Paulbus
- Take the train from St. Paul-Minneapolis to Milwaukeetrain
- Take the bus from Milwaukee to Appletonbus
14h 53m$165–303
Iowa to Appleton by bus
Comparing Your Travel Options
The cheapest way to get from Iowa to Appleton is to drive which costs $65 - $100 and takes 7h 7m.
The fastest way to get from Iowa to Appleton is to fly which takes 3h 58m and costs $100 - $490.
No, there is no direct bus from Iowa to Appleton. However, there are services departing from Des Moines and arriving at Appleton Valley Transit via Owatonna, Rochester and La Crosse Grand River Station. The journey, including transfers, takes approximately 14h 5m.
The distance between Iowa and Appleton is 335 miles. The road distance is 382.5 miles.
The best way to get from Iowa to Appleton without a car is to bus via La Crosse which takes 14h 5m and costs $110 - $190.
It takes approximately 3h 58m to get from Iowa to Appleton, including transfers.
Iowa to Appleton bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Iowa to Appleton is to fly which takes 3h 58m and costs $100 - $490. Alternatively, you can bus via La Crosse, which costs $110 - $190 and takes 14h 5m.
Iowa to Appleton bus services, operated by Jefferson Lines, arrive at Owatonna station.
Yes, the driving distance between Iowa to Appleton is 383 miles. It takes approximately 7h 7m to drive from Iowa to Appleton.
What companies run services between Iowa, USA and Appleton, WI, USA?
Delta, United Airlines, and American Airlines fly from Des Moines (DSM) to Appleton International Airport (ATW) hourly. Alternatively, you can take a bus from Des Moines to Appleton Valley Transit via Owatonna, Rochester, and La Crosse Grand River Station in around 14h 5m.
- Website
- united.com
Flights from Des Moines to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $75–450
Flights from Des Moines to Appleton International Airport via Denver
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $160–750
Flights from Quad City International Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $45–320
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Paul-Minneapolis to Milwaukee
- Ave. Duration
- 5h 48m
- Frequency
- 3 times a day
- Estimated price
- $85–190
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Owatonna
- Ave. Duration
- 4h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Rochester to La Crosse
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
Bus from Des Moines to Minneapolis
- Ave. Duration
- 5h 45m
- Frequency
- 3 times a day
- Estimated price
- $65–90
- Book at
- Jefferson Lines
- Adult
- $65–90
Bus from Des Moines to St. Paul
- Ave. Duration
- 4h 40m
- Frequency
- Twice daily
- Estimated price
- $60–90
- Book at
- Jefferson Lines
- Adult
- $60–90
Want to know more about travelling around United States
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Booking & Getting There
There are 66+ hotels available in Appleton.







