There are 4 ways to get from Iowa State University to St. Louis by shuttle, plane, bus (Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle, fly
best- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
3h 45m$215–1,193Bus, train
cheapest- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Kansas Citybus
- Take the train from Kansas City to St. Louistrain
12h 44m$51–181Bus
- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
10h 22m$56–191Drive 362 mi
- Drive from Iowa State University to St. Louiscar 362 mi
7h 10m$67–96
Iowa State University to St. Louis by foot and bus
Questions & Answers
The cheapest way to get from Iowa State University to St. Louis is to drive which costs $65 - $100 and takes 7h 10m.
The fastest way to get from Iowa State University to St. Louis is to shuttle and fly which takes 3h 45m and costs $210 - $1,200.
No, there is no direct bus from Iowa State University to St. Louis station. However, there are services departing from Ames and arriving at St Louis Bus Station via Des Moines and Kansas City Bus Station. The journey, including transfers, takes approximately 10h 22m.
The distance between Iowa State University and St. Louis is 317 miles. The road distance is 364.1 miles.
The best way to get from Iowa State University to St. Louis without a car is to bus which takes 10h 22m and costs $55 - $200.
It takes approximately 3h 45m to get from Iowa State University to St. Louis, including transfers.
Iowa State University to St. Louis bus services, operated by Jefferson Lines, depart from Ames station.
Iowa State University to St. Louis bus services, operated by Jefferson Lines, arrive at Des Moines station.
Yes, the driving distance between Iowa State University to St. Louis is 364 miles. It takes approximately 7h 10m to drive from Iowa State University to St. Louis.
There are 481+ hotels available in St. Louis.
What companies run services between Iowa State University, IA, USA and St. Louis, MO, USA?
You can take a vehicle from Iowa State University to St Louis Bus Station via Ames, Des Moines, and Kansas City Bus Station in around 10h 22m.
- Website
- southwest.com
Flights from Des Moines to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $130–1,000
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Ames to Des Moines
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $3–45
- Book at
- https://www.jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $35–60
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide









