There are 3 ways to get from Iowa City to Kirksville by bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, train  •  6 h 47 min

  1. Take the bus from Iowa City, IA to Davenport, IA
  2. Take the bus from Davenport, IA to Galesburg Amtrak
  3. Take the train from Galesburg Amtrak to La Plata Amtrak

$111 - $196

Cheapest option

Bus  •  13 h 26 min

  1. Take the bus from Iowa City, IA to Burlington, IA
  2. Take the bus from Burlington, IA to St Louis, MO
  3. Take the bus from St Louis, Mo to Kirksville

$103 - $218

1 alternative option

Drive  •  3 h 7 min

  1. Drive from Iowa City to Kirksville 160.5 miles

$15 - $23

What companies run services between Iowa City, IA, USA and Kirksville, MO, USA?

You can take a bus from Iowa City to Kirksville via Burlington, IA, St Louis, MO, Civic Center Transit Center, Cass @ 20Th Street Wb, and St Louis, Mo in around 13 h 26 min.

Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Galesburg Amtrak to La Plata Amtrak
Ave. Duration
2 h 13 min
Frequency
Twice daily
Estimated price
$30 - $80
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$60 - $85
Business Coach Seat
$55 - $80
Room
$170 - $240
Bus operators
Burlington Trailways
Website
burlingtontrailways.com
Bus from Iowa City, IA to Davenport, IA
Ave. Duration
1 h 12 min
Frequency
Hourly
Estimated price
$25 - $40
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Davenport, IA to Galesburg Amtrak
Ave. Duration
1 h 5 min
Frequency
4 times a day
Estimated price
$25 - $40
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Iowa City, IA to Burlington, IA
Ave. Duration
1 h 25 min
Frequency
Twice daily
Estimated price
$27 - $50
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Burlington, IA to St Louis, MO
Ave. Duration
4 h 55 min
Frequency
Once daily
Estimated price
$45 - $100
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Kirksville
Ave. Duration
4 h 40 min
Frequency
Every 4 hours
Estimated price
$28 - $70
Website
greyhound.com
Economy
$28 - $45
Flexible
$50 - $70

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

How far is it from Iowa City to Kirksville?

The distance between Iowa City and Kirksville is 186 km. The road distance is 257 km.

What is the cheapest way to get from Iowa City to Kirksville?

The cheapest way to get from Iowa City to Kirksville is to drive which costs $15 - $23 and takes 3 h 7 min.

What is the fastest way to get from Iowa City to Kirksville?

The quickest way to get from Iowa City to Kirksville is to drive which takes 3 h 7 min and costs $15 - $23.

Is there a direct bus between Iowa City and Kirksville?

No, there is no direct bus from Iowa City to Kirksville. However, there are services departing from Iowa City, IA and arriving at Kirksville via Burlington, IA, Civic Center Transit Center and St Louis, Mo. The journey, including transfers, takes approximately 13 h 26 min.

How long does it take to get from Iowa City to Kirksville?

It takes approximately 6 h 47 min to get from Iowa City to Kirksville, including transfers.