There are 5 ways to get from Iowa City to Chicago by bus (Greyhound), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Iowa City to Chicago Bus Stationbus Greyhound US0123 / ...
4h 45m$30–60Drive 220.7 mi
- Drive from Iowa City to Chicagocar 220.7 mi
3h 46m$41–59Drive to Burlington Municipal Airport, fly
- Drive from Iowa City to Burlington Municipal Airport (BRL)car
- Fly from Burlington Municipal Airport (BRL) to Chicago O'Hare International Airport (ORD)plane BRL - ORD
3h 28m$56–146Bus to Quad City International Airport, fly
- Take the bus from Iowa City to Moline Center Stationbus
- Fly from Quad City International Airport (MLI) to Chicago O'Hare International Airport (ORD)plane MLI - ORD
5h 23m$55–269Bus to The Eastern Iowa Airport, fly
- Take the bus from Court St Transportation Center to GTC Bay 9bus
- Fly from The Eastern Iowa Airport (CID) to Chicago O'Hare International Airport (ORD)plane CID - ORD
5h 22m
Iowa City to Chicago by bus (Greyhound)
Questions & Answers
The cheapest way to get from Iowa City to Chicago is to bus which costs $30 - $60 and takes 4h 45m.
The fastest way to get from Iowa City to Chicago is to drive and fly which takes 3h 28m and costs $55 - $150.
Yes, there is a direct bus departing from Iowa City and arriving at Chicago Bus Station station. Services depart twice daily, and operate every day. The journey takes approximately 4h 45m.
The distance between Iowa City and Chicago is 224 miles. The road distance is 221.9 miles.
The best way to get from Iowa City to Chicago without a car is to bus which takes 4h 45m and costs $30 - $60.
The bus from Iowa City to Chicago Bus Station takes 4h 45m including transfers and departs twice daily.
Iowa City to Chicago bus services, operated by Greyhound USA, depart from Iowa City station.
Iowa City to Chicago bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Iowa City to Chicago is 222 miles. It takes approximately 3h 46m to drive from Iowa City to Chicago.
Book your Iowa City to Chicago bus tickets online with Omio and FlixBus.
What companies run services between Iowa City, IA, USA and Chicago, IL, USA?
Greyhound USA operates a bus from Iowa City to Chicago Bus Station twice daily. Tickets cost $30–60 and the journey takes 4h 45m.
- Website
- united.com
Flights from Quad City International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $27–210
Flights from The Eastern Iowa Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $30–220
- Website
- aa.com
Flights from Quad City International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $27–210
Flights from The Eastern Iowa Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $30–220
- Website
- contouraviation.com
Flights from Burlington Municipal Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $40–120
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Iowa City to Chicago Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from Iowa City to Moline Center Station
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $25–55
- Website
- https://www.greyhound.com/
- Phone
- +1-319-362-0375
- Website
- 380express.com
Bus from Court St Transportation Center to GTC Bay 9
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Website
- https://www.380express.com
- Schedules at
- https://www.380express.com/schedule/
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