Swiss Railways (SBB/CFF/FFS) operates a train from Interlaken to Domodossola hourly. Tickets cost $12 - $23 and the journey takes 16 min. 3 other operators also service this route.
How to get from Interlaken to Domodossola
From Interlaken West train to Spiez, train to Brig, then train to Domodossola. 2 h 2 min SFr 50. From Interlaken West train to Spiez then train to Domodossola. 2 h 22 min SFr 46. From Interlaken drive to Domodossola. 3 h 40 min SFr 49.
Is there a direct train between Interlaken and Domodossola?
No, there is no direct train from Interlaken to Domodossola. However, there are services departing from Interlaken West and arriving at Domodossola via Spiez and Brig. The journey, including transfers, takes approximately 2 h 2 min.