Travel from Indianapolis to South-Carolina

Train, bus or fly from Indianapolis to South Carolina?

American Airlines, Southwest Airlines and 2 other airlines fly from Indianapolis to Rock Hill hourly. Alternatively, Megabus operates a bus from Indianapolis to Columbia twice daily. Tickets cost $50 - $65 and the journey takes 10 h 47 min. Megabus also services this route 5 times a day.

Travel Guides

Need to know: GreyhoundRome2rio’s guide on the bus operator has all the information you need
Want to know more about US trains?Rome2rio has everything you need to know about travelling with Amtrak

How to get from Indianapolis to South Carolina

From Washington St & Illinois St line 8 bus to Indianapolis airport, fly to Charlotte airport, then taxi to Rock Hill. 3 h 51 min $361. From Washington St & Illinois St line 8 bus to Indianapolis airport, fly to Florence airport, then taxi to Florence. 5 h 2 min $661. From Washington St & Illinois St line 8 bus to Indianapolis airport, fly to Greenville/Spartanburg airport, then taxi to Greenville. 5 h 15 min $541. From Washington St & Illinois St line 8 bus to Indianapolis airport, fly to Charleston airport, line 11 bus to N. Charleston SuperStop on Rivers Ave, then line 10 bus to North Charleston. 6 h 12 min $605. From Indianapolis, IN bus to Atlanta, GA - Marta Civic Center Station then bus to Columbia. 15 h 27 min $81. From Indianapolis, IN bus to Atlanta, GA then bus to Columbia. 18 h 42 min $99. From Indianapolis Amtrak train to Alexandria Amtrak then train to Columbia Amtrak. 29 h 15 min $353. From Indianapolis drive to Columbia. 10 h 25 min $74.
Close Print Itinerary
  1. Here are 8 options to get from
    Indianapolis to South Carolina:

    1. Trip:
      1 Fly to Charlotte
      • One-Way approx: USD $227 - $392
      • Duration: 3 h 51 min
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      • Trip:
        1 Fly to Charlotte
        • One-Way approx: USD $227 - $392
        • Duration: 3 h 51 min
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    2. Trip:
      2 Fly to Florence
      • One-Way approx: USD $250 - $1,213
      • Duration: 5 h 2 min
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      • Trip:
        2 Fly to Florence
        • One-Way approx: USD $250 - $1,213
        • Duration: 5 h 2 min
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    3. Trip:
      3 Fly to Greenville/Spartanburg
      • One-Way approx: USD $202 - $947
      • Duration: 5 h 15 min
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      • Trip:
        3 Fly to Greenville/Spartanburg
        • One-Way approx: USD $202 - $947
        • Duration: 5 h 15 min
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    4. Trip:
      4 Fly to Charleston
      • One-Way approx: USD $225 - $1,108
      • Duration: 6 h 12 min
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      • Trip:
        4 Fly to Charleston
        • One-Way approx: USD $225 - $1,108
        • Duration: 6 h 12 min
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    5. Trip:
      5 Bus Megabus
      • One-Way approx: USD $71 - $98
      • Duration: 15 h 27 min
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      • Trip:
        5 Bus Megabus
        • One-Way approx: USD $71 - $98
        • Duration: 15 h 27 min
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    6. Trip:
      6 Bus Greyhound USA
      • One-Way approx: USD $85 - $184
      • Duration: 18 h 42 min
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      • Trip:
        6 Bus Greyhound USA
        • One-Way approx: USD $85 - $184
        • Duration: 18 h 42 min
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    7. Trip:
      7 Train
      • One-Way approx: USD $176 - $490
      • Duration: 29 h 15 min
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      • Trip:
        7 Train
        • One-Way approx: USD $176 - $490
        • Duration: 29 h 15 min
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    8. Trip:
      8 Drive
      • One-Way approx: USD $60 - $90
      • Duration: 10 h 25 min
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      • Trip:
        8 Drive
        • One-Way approx: USD $60 - $90
        • Duration: 10 h 25 min
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