There are 4 ways to get from Indianapolis to San Diego by plane, bus (Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Indianapolis (IND) to San Diego International Airport (SAN)IND - SAN
6h 16m$292–372Bus
cheapest- Take the bus from Indianapolis Union Station to St Louis Bus Station
- Take the bus from St Louis Bus Station to Los Angeles Union Station
- Take the bus from Los Angeles Union Station to San Diego
2d$182–587Train (Amtrak)
- Take the train from Indianapolis to Chicago Union Station
- Take the train from Chicago Union Station to Fullerton Amtrak Station
- Take the train from Fullerton Amtrak Station to San Diego
2d 4h$288–703Drive 2,039.4 mi
- Drive from Indianapolis to San Diego2,039.4 mi
33h$373–538
Indianapolis to San Diego by bus
Questions & Answers
The cheapest way to get from Indianapolis to San Diego is to bus which costs $180 - $600 and takes 2 days 0h.
The fastest way to get from Indianapolis to San Diego is to fly which takes 6h 16m and costs $290 - $380.
No, there is no direct bus from Indianapolis station to San Diego. However, there are services departing from Indianapolis Union Station and arriving at San Diego via St Louis Bus Station and Los Angeles Union Station. The journey, including transfers, takes approximately 2 days 0h.
No, there is no direct train from Indianapolis to San Diego. However, there are services departing from Indianapolis and arriving at San Diego via Chicago Union Station and Fullerton Amtrak Station. The journey, including transfers, takes approximately 2 days 4h.
The distance between Indianapolis and San Diego is 1805 miles. The road distance is 2051.3 miles.
The best way to get from Indianapolis to San Diego without a car is to bus which takes 2 days 0h and costs $180 - $600.
It takes approximately 6h 16m to get from Indianapolis to San Diego, including transfers.
Indianapolis to San Diego bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
Indianapolis to San Diego train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to San Diego is to fly which takes 6h 16m and costs $290 - $380. Alternatively, you can bus, which costs $180 - $600 and takes 2 days 0h, you could also train, which costs $280 - $750 and takes 2 days 4h.
What companies run services between Indianapolis, IN, USA and San Diego, CA, USA?
Southwest Airlines, Frontier Airlines, and American Airlines fly from Indianapolis (IND) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a bus from Indianapolis Union Station to San Diego via St Louis Bus Station and Los Angeles Union Station in around 2d.
- Website
- southwest.com
Flights from Indianapolis to San Diego International Airport
- Ave. Duration
- 4h 30m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $200–900
Flights from Indianapolis to San Diego International Airport via Phoenix
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $200–900
Flights from Indianapolis to San Diego International Airport via Las Vegas
- Ave. Duration
- 6h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $210–900
Flights from Indianapolis to San Diego International Airport via Denver
- Ave. Duration
- 6h 33m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- $210–900
Flights from Indianapolis to San Diego International Airport via Chicago Midway
- Ave. Duration
- 6h 25m
- When
- Sunday
- Estimated price
- $210–900
- Website
- flyfrontier.com
Flights from Indianapolis to San Diego International Airport via Denver
- Ave. Duration
- 6h 21m
- When
- Thursday to Sunday
- Estimated price
- $210–900
- Website
- aa.com
Flights from Indianapolis to San Diego International Airport via Phoenix
- Ave. Duration
- 6h 39m
- When
- Monday, Thursday, and Sunday
- Estimated price
- $200–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $40–230
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Twice daily
- Estimated price
- $210–440
- Website
- https://www.amtrak.com/home.html
Train from Fullerton Amtrak Station to San Diego
- Ave. Duration
- 2h 23m
- Frequency
- Every 2 hours
- Estimated price
- $33–34
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $35–110
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Los Angeles Union Station
- Ave. Duration
- 38h 45m
- Frequency
- Twice daily
- Estimated price
- $120–410
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Los Angeles Union Station to San Diego
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $24–70
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Indianapolis to San Diego bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
San Diego is 3h behind Indianapolis. It is currently 12:52 PM in Indianapolis and 9:52 AM in San Diego.
Indianapolis to San Diego train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Indianapolis to San Diego is 2051 miles. It takes approximately 33h to drive from Indianapolis to San Diego.
Book your Indianapolis to San Diego train tickets online with Omio.
Book your Indianapolis to San Diego bus tickets online with Omio and FlixBus.
There are 2167+ hotels available in San Diego.







