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There are 6 ways to get from Indianapolis to Poplar Bluff by bus, taxi, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, taxi  •  10 h 55 min

  1. Take the bus from Indianapolis, IN to Champaign, IL
  2. Take the bus from Champaign, Il to St Louis, Mo
  3. Take the bus from St Louis, Mo to Sikeston, Mo
  4. Take a taxi from Sikeston, Mo to Poplar Bluff

$165 - $263

Cheapest option

Bus, train  •  11 h 53 min

  1. Take the bus from Indianapolis, IN to Bloomington/Normal, IL 1401 / ...
  2. Take the train from Bloomington-Normal Uptown Station to Poplar Bluff Amtrak Station Texas Eagle

$88 - $196

4 alternative options

Train  •  15 h 57 min

  1. Take the train from Indianapolis Amtrak Station to Chicago Union Station Hoosier State / ...
  2. Take the train from Chicago Union Station to Poplar Bluff Amtrak Station Texas Eagle

$111 - $288

Drive  •  6 h 27 min

  1. Drive from Indianapolis to Poplar Bluff 376.2 miles

$35 - $55

Fly to Cape Girardeau, drive  •  7 h 5 min

  1. Fly from Indianapolis (IND) to Cape Girardeau (CGI) IND - CGI
  2. Drive from Cape Girardeau to Poplar Bluff

$179 - $863

Fly to St. Louis, train  •  10 h 21 min

  1. Fly from Indianapolis (IND) to St. Louis (STL) IND - STL
  2. Take the train from St. Louis Gateway Station to Poplar Bluff Amtrak Station

$200 - $945

Questions & Answers

The cheapest way to get from Indianapolis to Poplar Bluff is to drive which costs $35 - $55 and takes 6 h 27 min.

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The quickest way to get from Indianapolis to Poplar Bluff is to drive which costs $35 - $55 and takes 6 h 27 min.

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No, there is no direct train from Indianapolis station to Poplar Bluff station. However, there are services departing from Indianapolis Amtrak Station and arriving at Poplar Bluff Amtrak Station via Chicago Union Station. The journey, including transfers, takes approximately 15 h 57 min.

More details

The distance between Indianapolis and Poplar Bluff is 312 miles. The road distance is 376.2 miles.

Get driving directions

The best way to get from Indianapolis to Poplar Bluff without a car is to bus and taxi which takes 10 h 55 min and costs $160 - $270.

More details

It takes approximately 10 h 55 min to get from Indianapolis to Poplar Bluff, including transfers.

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Indianapolis to Poplar Bluff train services, operated by Amtrak, arrive at Indianapolis Amtrak Station.

More details

There is no direct flight from Indianapolis Airport to Cape Girardeau Airport. The quickest flight takes 3 h 51 min and has one stopover.

Search flights

Poplar Bluff is 1 h behind Indianapolis. It is currently 7:08 PM in Indianapolis and 6:08 PM in Poplar Bluff.

Indianapolis to Poplar Bluff train services, operated by Amtrak, arrive at Poplar Bluff Amtrak Station.

More details

Map of how to get from Indianapolis to Poplar Bluff.
Launch map view
  • Distance: 311.7 miles
  • Duration: 10 h 55 min

What companies run services between Indianapolis, IN, USA and Poplar Bluff, MO, USA?

You can take a train from Indianapolis to Poplar Bluff via Chicago Union Station in around 15 h 57 min.

Airlines
United Airlines
Website
united.com
Flights from Indianapolis to Cape Girardeau via Chicago O'Hare
Ave. Duration
4 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $850
Flights from Indianapolis to Cape Girardeau via Chicago O'Hare, Paducah
Ave. Duration
5 h 18 min
When
Every day
Estimated price
$180 - $850
Flights from Indianapolis to St. Louis via Chicago O'Hare
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$180 - $900
Flights from Indianapolis to St. Louis via Toronto
Ave. Duration
4 h 47 min
When
Every day
Estimated price
$270 - $1,000
Flights from Indianapolis to St. Louis via Washington Dulles
Ave. Duration
4 h 54 min
When
Monday to Friday
Estimated price
$230 - $1,100
Delta
Website
delta.com
Flights from Indianapolis to St. Louis via Atlanta
Ave. Duration
4 h 42 min
When
Every day
Estimated price
$190 - $950
Flights from Indianapolis to St. Louis via Detroit
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$170 - $900
Air Canada
Website
aircanada.com
Flights from Indianapolis to St. Louis via Chicago O'Hare
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$180 - $900
Flights from Indianapolis to St. Louis via Toronto
Ave. Duration
4 h 47 min
When
Every day
Estimated price
$270 - $1,000
American Airlines
Website
aa.com
Flights from Indianapolis to St. Louis via Chicago O'Hare
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$160 - $850
Southwest Airlines
Website
southwest.com
Flights from Indianapolis to St. Louis via Atlanta
Ave. Duration
4 h 16 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $900
Flights from Indianapolis to St. Louis via Chicago Midway
Ave. Duration
4 h 55 min
When
Sunday
Estimated price
$170 - $800
Flights from Indianapolis to St. Louis via Kansas City
Ave. Duration
5 h
When
Monday to Friday
Estimated price
$200 - $850
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Bloomington-Normal Uptown Station to Poplar Bluff Amtrak Station
Ave. Duration
7 h 38 min
Frequency
Once daily
Estimated price
$55 - $150
Website
amtrak.com
Coach Seat
$55 - $85
Flexi Coach Seat
$95 - $140
Business Coach Seat
$100 - $150
Room
$250 - $350
Train from Indianapolis Amtrak Station to Chicago Union Station
Ave. Duration
5 h
Frequency
Once daily
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
Train from Chicago Union Station to Poplar Bluff Amtrak Station
Ave. Duration
9 h 57 min
Frequency
Once daily
Estimated price
$70 - $190
Website
amtrak.com
Coach Seat
$70 - $110
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$300 - $420
Train from St. Louis Gateway Station to Poplar Bluff Amtrak Station
Ave. Duration
3 h 47 min
Frequency
Once daily
Estimated price
$35 - $90
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$65 - $95
Business Coach Seat
$60 - $90
Room
$180 - $260
Bus operators
Burlington Trailways
Website
burlingtontrailways.com
Bus from Indianapolis, IN to Champaign, IL
Ave. Duration
2 h 5 min
Frequency
Once daily
Estimated price
$27 - $40
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Indianapolis, IN to Bloomington/Normal, IL
Ave. Duration
3 h 15 min
Frequency
Once daily
Estimated price
$30 - $50
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Champaign, Il to St Louis, Mo
Ave. Duration
3 h
Frequency
Every 4 hours
Estimated price
$23 - $55
Website
greyhound.com
Economy
$23 - $35
Flexible
$40 - $55
Bus from St Louis, Mo to Sikeston, Mo
Ave. Duration
2 h 45 min
Frequency
Once daily
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Other operators
Taxi from Sikeston, Mo to Poplar Bluff
Ave. Duration
1 h 5 min
Estimated price
$95 - $120

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Indianapolis to Poplar Bluff is 376 miles. It takes approximately 6 h 27 min to drive from Indianapolis to Poplar Bluff.

Get driving directions

American Airlines and United Airlines offer flights from Indianapolis Airport to Cape Girardeau Airport.

Search flights

Book your Indianapolis to Poplar Bluff train tickets online with Rome2rio.

Search and book

There are eight+ hotels available in Poplar Bluff. Prices start at $100 USD per night.

More details

The best way to get from Indianapolis to Indianapolis Airport is to line 8 bus which takes 39 min and costs $2.

More details