There are 6 ways to get from Indianapolis to Pittsburgh by bus (Greyhound, Flixbus), train (Amtrak), car, plane, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Indianapolis Union Station to Pittsburgh Intermodal StationGreyhound US0421
8h 45m$40–95Train (Amtrak)
- Take the train from Indianapolis to Chicago Union StationCardinal
- Take the train from Chicago Union Station to Pittsburgh Amtrak StationFloridian
15h 25m$126–498Drive 356.9 mi
- Drive from Indianapolis to Pittsburgh356.9 mi
6h 1m$66–95Fly from Indianapolis
- Fly from Indianapolis (IND) to Pittsburgh International Airport (PIT)IND - PIT
6h 39m$152–332Train to Purdue University Airport, fly
- Take the train from Indianapolis to Lafayette Amtrak Station
- Fly from Purdue University Airport (LAF) to Pittsburgh International Airport (PIT)LAF - PIT
8h 37m$92–422Bus to Chicago O'Hare International Airport, fly
- Take the bus from Indianapolis to Chicago Bus Station
- Fly from Chicago O'Hare International Airport (ORD) to Pittsburgh International Airport (PIT)ORD - PIT
8h 21m$134–384
Indianapolis to Pittsburgh by bus
Questions & Answers
The cheapest way to get from Indianapolis to Pittsburgh is to bus which costs $40 - $95 and takes 8h 45m.
The fastest way to get from Indianapolis to Pittsburgh is to drive which takes 6h 1m and costs $65 - $95.
Yes, there is a direct bus departing from Indianapolis Union Station station and arriving at Pittsburgh Intermodal Station station. Services depart four times a day, and operate every day. The journey takes approximately 8h 45m.
No, there is no direct train from Indianapolis to Pittsburgh station. However, there are services departing from Indianapolis and arriving at Pittsburgh Amtrak Station via Chicago Union Station. The journey, including transfers, takes approximately 15h 25m.
The distance between Indianapolis and Pittsburgh is 366 miles. The road distance is 359 miles.
The best way to get from Indianapolis to Pittsburgh without a car is to bus which takes 8h 45m and costs $40 - $95.
The bus from Indianapolis, Illinois St (Greyhound Bus Station) to Pittsburgh Intermodal Station takes 8h 45m including transfers and departs four times a day.
Indianapolis to Pittsburgh bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
Indianapolis to Pittsburgh train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to Pittsburgh is to bus which takes 8h 45m and costs $40 - $95. Alternatively, you can train, which costs $120 - $500 and takes 15h 25m, you could also fly, which costs $150 - $340 and takes 6h 39m.
What companies run services between Indianapolis, IN, USA and Pittsburgh, PA, USA?
Greyhound USA operates a bus from Indianapolis Union Station to Pittsburgh Intermodal Station 3 times a day. Tickets cost $40–75 and the journey takes 8h 45m. Flixbus USA also services this route once daily. Alternatively, you can take a train from Indianapolis to Pittsburgh Amtrak Station via Chicago Union Station in around 15h 25m.
- Website
- united.com
Flights from Indianapolis to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $85–480
Flights from Indianapolis to Pittsburgh International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $80–460
Flights from Purdue University Airport to Pittsburgh International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $65–370
Flights from Chicago O'Hare International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $50–310
- Website
- aa.com
Flights from Indianapolis to Pittsburgh International Airport via Reagan Washington
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–490
Flights from Indianapolis to Pittsburgh International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $80–460
Flights from Chicago O'Hare International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $50–310
- Website
- southwest.com
Flights from Indianapolis to Pittsburgh International Airport via Chicago Midway
- Ave. Duration
- 4h 11m
- When
- Wednesday, Thursday, and Saturday
- Estimated price
- $80–450
Flights from Indianapolis to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $90–490
Flights from Indianapolis to Pittsburgh International Airport via Nashville
- Ave. Duration
- 6h 12m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–490
- Website
- delta.com
Flights from Indianapolis to Pittsburgh International Airport via Detroit
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $70–420
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $35–300
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Pittsburgh Amtrak Station
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $90–200
- Website
- https://www.amtrak.com/home.html
Train from Indianapolis to Lafayette Amtrak Station
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a week
- Estimated price
- $25–55
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to Pittsburgh Intermodal Station
- Ave. Duration
- 8h 45m
- Frequency
- 3 times a day
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Indianapolis Union Station to Pittsburgh Intermodal Station
- Ave. Duration
- 7h
- Frequency
- Once daily
- Estimated price
- $40–95
- Schedules at
- flixbus.com
- Adult
- $40–95
Bus from Indianapolis to Chicago Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Every 4 hours
- Estimated price
- $35–80
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Indianapolis to Pittsburgh bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
Indianapolis to Pittsburgh train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Indianapolis to Pittsburgh is 359 miles. It takes approximately 6h 1m to drive from Indianapolis to Pittsburgh.
Book your Indianapolis to Pittsburgh train tickets online with Omio.
Book your Indianapolis to Pittsburgh bus tickets online with Omio and FlixBus.
There are 728+ hotels available in Pittsburgh.







