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How to get fromIndianapolis to Irvineby plane, bus (Greyhound), bus, train or car

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There are 8 ways to get from Indianapolis to Irvine by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Indianapolis to John Wayne Airport Orange County

    best
    1. Fly from Indianapolis (IND) to John Wayne Airport Orange County (SNA)plane plane IND - SNA
    8h 11m
    $182–852

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    3. Take the bus from Los Angeles Union Station to Anaheim Regional Transportation Intermodal Centerbus bus
    47h 7m
    $165–563

  3. Bus, train

    1. Take the bus from Indianapolis to Chicago Bus Stationbus bus FlixBus 2512 / ...
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2d
    $250–1,470

  4. Drive 2,048.9 mi

    1. Drive from Indianapolis to Irvinecar car 2,048.9 mi
    32h 47m
    $374–541

  5. Fly Indianapolis to Los Angeles International Airport, train

    1. Fly from Indianapolis (IND) to Los Angeles International Airport (LAX)plane plane IND - LAX
    2. Take the train from L.A. Union Station to Tustintrain train
    9h 50m
    $191–517

  6. Fly Indianapolis to Burbank Bob Hope Airport, train

    1. Fly from Indianapolis (IND) to Burbank Bob Hope Airport (BUR)plane plane IND - BUR
    2. Take the train from L.A. Union Station to Tustintrain train
    9h 48m
    $205–670

  7. Bus to Chicago O'Hare International Airport, fly to John Wayne Airport Orange County

    1. Take the bus from Indianapolis to Chicago Bus Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to John Wayne Airport Orange County (SNA)plane plane ORD - SNA
    10h 8m
    $170–621

  8. Fly Indianapolis to San Diego International Airport, train

    1. Fly from Indianapolis (IND) to San Diego International Airport (SAN)plane plane IND - SAN
    2. Take the train from San Diego Old Town Transportation Center to Irvinetrain train
    10h 27m
    $240–1,036

Indianapolis to Irvine by bus (Greyhound)

Calendar12Weekly Buses
Duration47h 7mAverage Duration
Ticket$165Cheapest Price
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Questions & Answers

What companies run services between Indianapolis, IN, USA and Irvine, CA, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Indianapolis (IND) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a bus from Indianapolis Union Station to Main-Harvard via St Louis Bus Station, Los Angeles Union Station, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 47h 7m.

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