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How to get fromIndianapolis to Iowaby bus (Greyhound), car, or plane

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There are 5 ways to get from Indianapolis to Iowa by bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    10h
    $77–138

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Indianapolis (IND) to Quad City International Airport (MLI)plane plane IND - MLI
    6h 48m
    $59–374

  3. Drive 466.6 mi

    1. Drive from Indianapolis to Des Moinescar car 466.6 mi
    7h 55m
    $86–123

  4. Fly to Des Moines

    1. Fly from Indianapolis (IND) to Des Moines (DSM)plane plane IND - DSM
    6h 2m
    $139–773

  5. Fly to Omaha

    1. Fly from Indianapolis (IND) to Omaha (OMA)plane plane IND - OMA
    6h 1m
    $147–732

Indianapolis (IND) to Des Moines (DSM) flights

Calendar148Weekly Planes
Duration5h 45mAverage Duration
Ticket$123Cheapest Price
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Questions & Answers

Map of how to get from Indianapolis to Iowa.ExpandLaunch map view
  • Distance: 464.3 mi
  • Duration: 10h

What companies run services between Indianapolis, IN, USA and Iowa, USA?

Greyhound USA operates a bus from Indianapolis Union Station to Des Moines once daily. Tickets cost $65–130 and the journey takes 9h 55m. Alternatively, Delta, United Airlines, and three other airlines fly from Indianapolis (IND) to Des Moines (DSM) hourly.

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Bus operators

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